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  • Springer  (91)
  • American Meteorological Society  (18)
  • Nature Publishing Group
  • Copernicus
  • 2015-2019  (54)
  • 2000-2004  (40)
  • 1975-1979  (39)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 210 (2000), S. 157-161 
    ISSN: 1432-041X
    Keywords: Key words Swallow ; bicoid ; Drosophila ; mRNA localization ; Oogenesis ; Embryogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  We analyzed a functional homologue of the swallow gene from Drosophila pseudoobscura. The swallow gene of D. melanogaster plays an essential role in localizing bicoid mRNA in oocytes, and swallow mutant embryos show anterior pattern defects that result from the lack of localization of the bicoid morphogen. The pseudoobscura homologue rescues the function of swallow mutants when introduced into the genome of D. melanogaster, and its expression is similar to that of the melanogaster gene. The predicted pseudoobscura and melanogaster proteins are 49% identical and 69% conserved. The coiled-coil domain previously identified in the melanogaster swallow protein is strongly conserved in the pseudoobscura homologue, but the weak similarity of the melanogaster swallow protein to the RNP class of RNA-binding proteins is not conserved in the pseudoobscura homologue. These and other observations suggest a structural role for swallow in localizing bicoid mRNA, perhaps as part of the egg cytoskeleton.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0495
    Keywords: Key words Karst terranes ; Electrical resistivity tomography ; Sinkholes ; Pinnacles and cutters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Sinkhole collapse is one of the main limitations on the development of karst areas, especially where bedrock is covered by unconsolidated material. Studies of sinkhole formation have shown that sinkholes are likely to develop in cutter (enlarged joint) zones as a result of subterranean erosion by flowing groundwater. Because of the irregular distribution of pinnacles and cutters on the bedrock surface, uncertainties arise when "hit-or-miss" borehole drilling is used to locate potential collapse sites. A high-resolution geophysical technique capable of depicting the details of the bedrock surface is essential for guiding the drilling program. Dipole-dipole electrical resistivity tomography (ERT) was used to map the bedrock surface at a site in southern Indiana where limestone is covered by about 9 m of clayey soils. Forty-nine transects were conducted over an area of approximately 42,037 m2. The electrode spacing was 3 m. The length of the transects varied from 81 to 249 m. The tomographs were interpreted with the aid of soil borings. The repeatability of ERT was evaluated by comparing the rock surface elevations interpreted from pairs of transects where they crossed each other. The average difference was 2.4 m, with a maximum of 10 m. The discrepancy between interpreted bedrock-surface elevations for a transect intersection may be caused by variations in the subsurface geology normal to the transect. Averaging the elevation data interpreted from different transects improved the ERT results. A bedrock surface map was generated using only the averaged elevation data at the transect junctions. The accuracy of the map was further evaluated using data from four exploratory boreholes. The average difference between interpreted and actual bedrock surface-elevations was less than 0.4 m. The map shows two large troughs in the limestone surface: one coinciding with an existing sinkhole basin, while the other is in alignment with a small topographic valley. Because sinkholes were observed at the same elevation interval in similar valleys in the vicinity, the delineated trough may have implications for future land use at the site.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    The journal of membrane biology 47 (1979), S. 377-399 
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary A previous model of the mechanisms of flow through epithelia was modified and extended to include hydrostatic and osmotic pressures in the cells and in the peritubular capillaries. The differential equations for flow and concentration in each region of the proximal tubule were derived. The equations were solved numerically by a finite difference method. The principal conclusions are: (i) Cell NaCl concentration remains essentially isotonic over the pressure variations considered; (ii) channel NaCl concentration varies only a few mosmol from isotonicity, and the hydrostatic and osmotic pressure differences across the cell wall are of the same order of magnitude; (iii) both reabsorbate osmolality and pressure-induced flow are relatively insensitive to the geometry of the system; (iv) a strong equilibrating mechanism exists in the sensitivity of the reabsorbate osmolality to luminal osmolality; this mechanism is far more significant than any other parameter change.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 262 (1976), S. 554-559 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The translation product of the gag gene of mammalian type-C RNA viruses is a 65,000–68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. An immunological approach has been used to establish the arrangement ...
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of industrial microbiology and biotechnology 24 (2000), S. 267-274 
    ISSN: 1476-5535
    Keywords: Keywords: vitamins; activated sludge; industrial wastewater; porous pots; Amtox™
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The process performance and metabolic rates of samples of activated sludge dosed with vitamin supplements have been compared. After initial screening, four vitamins and two metals as single supplements and in pairs, were dosed continuously into the mixed liquor of an activated sludge simulation. Toxicity, oxygen demand removal, respiration rates and suspended solids were measured to monitor the effect on process efficiency. It was confirmed experimentally that an industrial wastewater stream did not contain a sufficient supply of micronutrients for efficient biological treatment. This was concluded from the observation that control sludge batches (receiving no supplements) averaged chemical oxygen demand removal efficiency of 58%. Dosing micronutrients into the mixed liquor produced removal efficiencies of up to 69%. Some of the supplements increased the respiration rate of the sludge while some decreased it, indicating a range of stimulatory and inhibitory effects. Complex interactions between micronutrients that were dosed simultaneously were evident. Several positive effects led to the conclusion that micronutrients have the potential to optimise process performance of activated sludge plants treating industrial wastewater. The addition of phosphorus/niacin and molybdenum/lactoflavin removed wastewater components that were toxic to nitrifiers as indicated through toxicity testing, thus protecting downstream nitrification/denitrification treatment processes. Journal of Industrial Microbiology & Biotechnology (2000) 24, 267–274.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of mathematical biology 40 (1978), S. 273-300 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Transient solutions are developed for the buildup of a concentration gradient in the single loop solute cycling model of the renal medulla. The “pump” from ascending limb to descending limb is considered in both unsaturated and completely saturated modes of operation. Both analytic solutions and semianalytic solutions obtained from inverting Laplace transforms are considered. The classic representation of concentration buildup by the multiplication process is compared with calculated profiles. The “single effect” is found to vary both in time and space.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 31 (1975), S. 1473-1474 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Coverslips coated with rat-tail collagen dried at 37°C were placed in a hot-air sterilizing oven at 160°C for 2 h. The resulting transparent sterile film was found to be a useful multipurpose substrate for cell culture and for subsequent histological sectioning.
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  • 8
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 282 (1979), S. 496-497 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Antarctic ice shelves are floating ice sheets varying in thickness from 100 m to more than 1,700 m. They rise and fall on the ocean tide, bending over a narrow region where they join the grounded ice sheet. The variation in theoretical surface elevation profiles over the duration of a tidal cycle ...
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 265 (1977), S. 318-319 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The spiral structure of our Galaxy indicates the regions where bright, short-lived stars illuminate the interstellar gas and dust. The two principal spiral arms are believed to reflect a self-sustaining density-wave pattern through which the disk of stars and gas move. Observations indicate dust ...
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 276 (1978), S. 697-698 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] To obtain a quantitative measure of surface located iron metal, a mild specific leaching agent was used. Although X-ray photoelectron spectroscopy (XPS)6,7 may distinguish between Fe(II) and Fe(0) at depths 〈 20 Å, this technique is not quantitative. Fe(0) is readily dissolved in a ...
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