Publication Date:
2017-12-05
Description:
Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death, Published online: 05 December 2017; doi:10.1038/s41467-017-02035-9 The differences in virus-host interactions resulting in distinct pathogenicity of seasonal and pandemic influenza A viruses (IAV) are not well understood. Here, the authors show that the hemagglutinin segment from pandemic, but not seasonal, IAV suppresses RIPK3-mediated dendritic cell death, thereby reducing T cell activation.
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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