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Description: IJERPH, Vol. 15, Pages 1907: Evaluation by the Ames Assay of the Mutagenicity of UV Filters Using Benzophenone and Benzophenone-1 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph15091907 Authors: Wen-Qian Wang Hai-Xin Duan Zhou-Tao Pei Rou-Rou Xu Ze-Tian Qin Guang-Can Zhu Li-Wei Sun Ultraviolet absorbing chemicals (UV filters) are widely used in personal care products for protecting human skin and hair from damage by UV radiation. Although these substances are released into the environment during production and consumption processes, little is known about their genotoxicity effects. Our previous studies have shown that benzophenone-type UV filters exhibited acute toxicity on three species of aquatic organisms. Mutagenesis by benzophenone (BP) and benzophenone-1(BP-1) was tested in the present study by the Salmonella typhimurium/reverse mutation assay (Ames assay). All the positive reverse mutations occurred in the absence of the S9 liver extract system for both chemicals. From BP, positive mutation effects on the TA102 strain at doses of 0.05 μg/plate and 0.5 μg/plate were detected. From BP-1, positive mutation effects on the TA97 strain at doses of 0.05 μg/plate and 0.5 μg/plate, and on the TA100 strain at a dose of 0.5 μg/plate, were detected. A mixture of BP and BP-1 exhibited mutagenicity on the TA97 and TA100 strains. For the TA97 strain, the positive mutation results were detected at 10% and 50% of the mixture. For the TA100 strain, the results were detected when the mixture was at 5% and 10%. In the mixture at 5%, the concentrations of BP and BP-1 were 3.5 μg/plate and 14 μg/plate, respectively. In the 10% mixture, the doses of BP and BP-1 were 7 μg/plate and 28 μg/plate, respectively. In the 50% mixture, the doses of BP and BP-1 were 35 μg/plate and 140 μg/plate, respectively. The mixture test results suggested that there was antagonism in mutagenicity between BP and BP-1.

Description: IJERPH, Vol. 14, Pages 1414: Acute Toxicity and Ecological Risk Assessment of Benzophenone-3 (BP-3) and Benzophenone-4 (BP-4) in Ultraviolet (UV)-Filters International Journal of Environmental Research and Public Health doi: 10.3390/ijerph14111414 Authors: Yang Du Wen-Qian Wang Zhou-Tao Pei Fahmi Ahmad Rou-Rou Xu Yi-Min Zhang Li-Wei Sun Ultraviolet (UV)-absorbing chemicals (UV filters) are used in personal care products for the protection of human skin and hair from damage by UV radiation. Although these substances are released into the environment in the production and consumption processes, little is known about their ecotoxicology effects. The acute toxicity and potential ecological risk of UV filters benzophenone-3 (BP-3) and benzophenone-4 (BP-4) on Chlorella vulgaris, Daphnia magna, and Brachydanio rerio were analyzed in the present study. The EC50 values (96 h) of BP-3 and BP-4 on C. vulgaris were 2.98 and 201.00 mg/L, respectively. The 48 h-LC50 of BP-3 and BP-4 on D. magna were 1.09 and 47.47 mg/L, respectively. The 96 h-LC50 of BP-3 and BP-4 on B. rerio were 3.89 and 633.00 mg/L, respectively. The toxicity of a mixture of BP-3 and BP-4 on C. vulgaris, D. magna, and B. rerio all showed antagonistic effects. The induced predicted no-effect concentrations of BP-3 and BP-4 by the assessment factor method were 1.80 × 10−3 and 0.47 mg/L, respectively, by assessment factor (AF) method, which were both lower than the concentrations detected in the environment at present, verifying that BP-3 and BP-4 remain low-risk chemicals to the aquatic ecosystem.

Description: Steep topographic reliefs and heavy vegetation severely limit visibility when examining geological structures and surface deformations in the field or when detecting these features with traditional approaches, such as aerial photography and satellite imagery. However, a light detection and ranging (LiDAR)-derived digital elevation model (DEM), which is directly related to the bare ground surface, is successfully employed to map topographic signatures with an appropriate scale and accuracy and facilitates measurements of fine topographic features. This study demonstrates the efficient use of 1-m-resolution LiDAR for tectonic geomorphology in forested areas and to identify a fault, a deep-seated landslide, and the regional cleavage attitude in southern Taiwan. Integrated approaches that use grayscale slope images, openness with a tint color slope visualization, the three-dimensional (3D) perspective of a red relief image map, and a field investigation are employed to identify the aforementioned features. In this study, the previously inferred Meilongshan Fault is confirmed as a NE–SW-trending, eastern dipping thrust with at least a 750 m-wide deformation zone. The site where future paleoseismological studies should be performed has been identified, and someone needs to work further on this site. Signatures of deep-seated landslides, such as double ridges, trenches, main escarpments, and extension cracks, are successfully differentiated in LiDAR DEM images through the use of different visualization techniques. Systematic parallel and continuous lineaments in the images are interpreted as the regional cleavage attitude of cleavage, and a field investigation confirms this interpretation.

Description: A highly ordered, mesoporous (pore size 2~50 nm) bioactive glass (MBG) structure has a greater surface area and pore volume and excellent bone-forming bioactivity compared with traditional bioactive glasses (BGs). Hence, MBGs have been used in drug delivery and bone tissue engineering. MBGs can be developed as either a dense or porous block. Compared with a block, microbeads provide greater flexibility for filling different-shaped cavities and are suitable for culturing cells in vitro. In contrast, the fibrous structure of a scaffold has been shown to increase cell attachment and differentiation due to its ability to mimic the three-dimensional structure of natural extracellular matrices. Hence, the aim of this study is to fabricate MBG microbeads with a fibrous structure. First, a sol-gel/electrospinning technique was utilized to fabricate the MBG nanofiber (MBGNF) structure. Subsequently, the MBGNF microbeads (MFBs) were produced by an electrospraying technology. The results show that the diameter of the MFBs decreases when the applied voltage increases. The drug loading and release profiles and mechanisms of the MFBs were also evaluated. MFBs had a better drug entrapment efficiency, could reduce the burst release of tetracycline, and sustain the release over 10 days. Hence, the MFBs may be suitable drug carriers. In addition, the cellular attachment of MG63 osteoblast-like cells is significantly higher for MFBs than for glass microbeads after culturing for 4 h. The nanofibrous structure of MFBs could provide an appropriate environment for cellular spreading. Therefore, MFBs have great potential for use as a bone graft material in bone tissue engineering applications.

Description: As the number of speech and video documents increases on the Internet and portable devices proliferate, speech summarization becomes increasingly essential. Relevant research in this domain has typically focused on broadcasts and news; however, the automatic summarization methods used in the past may not apply to other speech domains (e.g., speech in lectures). Therefore, this study explores the lecture speech domain. The features used in previous research were analyzed and suitable features were selected following experimentation; subsequently, a three-phase real-time speech summarizer for the learning of sustainability (RTSSLS) was proposed. Phase One involved selecting independent features (e.g., centrality, resemblance to the title, sentence length, term frequency, and thematic words) and calculating the independent feature scores; Phase Two involved calculating the dependent features, such as the position compared with the independent feature scores; and Phase Three involved comparing these feature scores to obtain weighted averages of the function-scores, determine the highest-scoring sentence, and provide a summary. In practical results, the accuracies of macro-average and micro-average for the RTSSLS were 70% and 73%, respectively. Therefore, using a RTSSLS can enable users to acquire key speech information for the learning of sustainability.

Description: Minerals, Vol. 8, Pages 385: Carbonaceous Materials in the Fault Zone of the Longmenshan Fault Belt: 1. Signatures within the Deep Wenchuan Earthquake Fault Zone and Their Implications Minerals doi: 10.3390/min8090385 Authors: Li-Wei Kuo Jyh-Rou Huang Jiann-Neng Fang Jialiang Si Haibing Li Sheng-Rong Song Graphitization of carbonaceous materials (CM) has been experimentally demonstrated as potential evidence of seismic slip within a fault gouge. The southern segment of the Longmenshan fault, a CM-rich-gouge fault, accommodated coseismic slip during the 2008 Mw 7.9 Wenchuan earthquake and potentially preserves a record of processes that occurred on the fault during the slip event. Here, we present a multi-technique characterization of CM within the active fault zone of the Longmenshan fault from the Wenchuan earthquake Fault Scientific Drilling-1. By contrast with field observations, graphite is pervasively and only distributed in the gouge zone, while heterogeneously crystallized CM are present in the surrounding breccia. The composite dataset that is presented, which includes the localized graphite layer along the 2008 Wenchuan earthquake principal slip zone, demonstrates that graphite is widely distributed within the active fault zone. The widespread occurrence of graphite, a seismic slip indicator, reveals that surface rupturing events commonly occur along the Longmenshan fault and are characteristic of this tectonically active region.

Description: This study uses three periods of airborne laser scanning (ALS) digital elevation model (DEM) data to analyze the short-term erosional features of the Tsaoling landslide triggered by the 1999 Chi-Chi earthquake in Taiwan. Two methods for calculating the bedrock incision rate, the equal-interval cross section selection method and the continuous swath profiles selection method, were used in the study after nearly ten years of gully incision following the earthquake-triggered dip-slope landslide. Multi-temporal gully incision rates were obtained using the continuous swath profiles selection method, which is considered a practical and convenient approach in terrain change studies. After error estimation and comparison of the multi-period ALS DEMs, the terrain change in different periods can be directly calculated, reducing time-consuming fieldwork such as installation of erosion pins and measurement of topographic cross sections on site. The gully bedrock incision rate calculated by the three periods of ALS DEMs on the surface of the Tsaoling landslide ranged from 0.23 m/year to 3.98 m/year. The local gully incision rate in the lower part of the landslide surface was found to be remarkably faster than that of the other regions, suggesting that the fast incision of the toe area possibly contributes to the occurrence of repeated landslides in the Tsaoling area.

Description: Minerals, Vol. 8, Pages 393: Carbonaceous Materials in the Fault Zone of the Longmenshan Fault Belt: 2. Characterization of Fault Gouge from Deep Drilling and Implications for Fault Maturity Minerals doi: 10.3390/min8090393 Authors: Li-Wei Kuo Jyh-Rou Huang Jiann-Neng Fang Jialiang Si Sheng-Rong Song Haibing Li En-Chao Yeh In recent works on the determination of graphitization of carbonaceous materials (CM) within the principal slip zone (PSZ) of the Longmenshan fault (China), we demonstrated that the formation of graphite, resulted from strain and frictional heating, could be evidence of past seismic slip. Here we utilize Raman Spectroscopy of CM (RSCM) on the CM-bearing gouges in the fault zone of the Longmenshan fault belt, at the borehole depth of 760 m (FZ760) from the Wenchuan earthquake Fault Scientific Drilling project-1 (WFSD-1), to quantitatively characterize CM and further retrieve ancient fault deformation information in the active fault. RSCM shows that graphitization of CM is intense in the fault core with respect to the damage zone, with the graphitized carbon resembling those observed on experimentally formed graphite that was frictionally generated. Importantly, compared to the recognized active fault zone of the Longmenshan fault, the RSCM of measured CM-rich gouge shows a higher degree of graphitization, likely derived from high-temperature-perturbation faulting events. It implies that FZ760 accommodated numerous single-event displacement and/or at higher normal stresses and/or in the absence of pore fluid and/or along a more localized slip surface(s). Because graphite is a well-known lubricant, we surmise that the presence of the higher degree graphitized CM within FZ760 will reduce the fault strength and inefficiently accumulate tectonic stress during the seismic cycle at the current depth, and further infer a plausible mechanism for fault propagation at the borehole depth of 590 m during the Mw 7.9 Wenchuan earthquake.

Description: The Tsaoling Landslide in Taiwan has captured attentions of researchers worldwide due to its frequent catastrophic failure and distinctive features. Thanks to the launch of TerraSAR-X/TanDEM-X (TSX/TDX) constellation, retrieval of global DEM with high spatial resolution and accuracy becomes possible, which is extremely useful for the study of natural hazards (e.g., landslides) globally. We attempt here for the first time to track recent landslide movements in Tsaoling Taiwan by analyzing DEM time series reconstructed from TSX/TDX image pairs. Quality improvement of InSAR derived DEM through an iterated differential operation is addressed during the data processing. Five cliffs and the Chingshui River are selected to determine the spatial pattern of morphologic changes of the landslide. The results show that: (a) A large amount of collapses occurred on dip slopes in the period from 2011 to 2014 and on surrounding debris deposits during the rainy seasons; (b) The average recession rate of the Chunqui Cliff decreased from 24.4 m/yr to 19.6 m/yr compared with the result between 1999 and 2009; (c) The Tsaoling Landslide has lost 6.90 ×106 m³ of soil from November of 2011 to April of 2014, which shows a positive correlation of 0.853 with rainfall; (d) The Chingshui River is undergoing a gradual bed erosion with a volumes of 1.84 ×106 m³.