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  • 1
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    Sensors, Vol. 19, Pages 3402: Development of a Dynamic Oriented Rehabilitative Integrated System (DORIS) and Preliminary Tests (2019)
    MDPI
    In: Sensors
    Details
    Publication Date: 2019
    Description: Moving platforms were introduced in the field of the study of posturography since the 1970s. Commercial platforms have some limits: a limited number of degrees of freedom, pre-configured protocols, and, usually, they are expensive. In order to overcome these limits, we developed a robotic platform: Dynamic Oriented Rehabilitative Integrated System (DORIS). We aimed at realizing a versatile solution that can be applied both for research purposes but also for personalizing the training of equilibrium and gait. We reached these goals by means of a Stewart platform that was realized with linear actuators and a supporting plate. Each actuator is provided by an ad hoc built monoaxial load cell. Position control allows a large range of movements and load cells measure the reactive force applied by the subject. Transmission Control Protocol/Internet Protocol (TCP/IP) guarantees the communication between the platform and other systems. We integrated DORIS with a motion analysis system, an electromyography (EMG) system, and a virtual reality environment (VR). This integration and the custom design of the platform offer the opportunity to manipulate the available information of the subject under analysis, which uses visual, vestibular, and plantar feet pressure inputs. The full access to the human movements and to the dynamic interaction is a further benefit for the identification of innovative solutions for research and physical rehabilitation purposes in a field that is widely investigated but still open.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by MDPI
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  • 2
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    IJERPH, Vol. 16, Pages 1098: Problematic Internet Use in University Students Attending Three Superior Graduate Schools in Italy: Is Autism Spectrum Related to Suicide Risk? (2019)
    MDPI
    Details
    Publication Date: 2019
    Description: Background: Over the past decades, problematic internet use (PIU) has dramatically increased, especially among young people. PIU has been recently associated with autism spectrum disorder (ASD) and autistic traits. Subjects with PIU report an increased suicidal risk and the same has been demonstrated among patients with ASD. The aim of this study was to investigate putative PIU rates among students and explore the correlation between autistic traits and suicide risk. Methods: A sample of 178 high achieving university students was assessed by means of the Adult Autism Subthreshold Spectrum (AdAS Spectrum), Autism Quotient questionnaire (AQ). Suicide risk was investigated by some specific items of the Trauma and Loss Spectrum-Self Report (TALS-SR) and putative PIU was identified on the basis of a specific AdAS Spectrum item. Results: 27.5% subjects reporting putative PIU. This subgroup showed higher scores in all domains of AdAS Spectrum and AQ compared with others. Students with putative PIU showed a significant correlation between suicide risk and the non-verbal communication domain of the AdAS Spectrum and the Social skills domain of the AQ. Conclusions: We found that students with PIU show higher levels of autistic traits compared to those without PIU. A significant correlation was found between autistic traits and suicide risk.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI
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  • 3
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    Sensors, Vol. 19, Pages 4852: Determination of Picomolar Concentrations of Paraoxon in Human Urine by Fluorescence-Based Enzymatic Assay (2019)
    MDPI
    In: Sensors
    Details
    Publication Date: 2019
    Description: Organophosphate (OP) pesticides are widely used in the agricultural field and in the prevention of pest infestation in private and public areas of cities. Despite their unquestionable utility, several of these compounds demonstrate toxic effects to the environment and human health. In particular, the occurrence of some organophosphate pesticides is correlated to the incidence of nervous system disorders, especially in children. The detection of pesticide residues in the human body represents an important task to preserve human health. In our work we propose the use of esterase-based biosensors as a viable alternative to the expensive and time-consuming systems currently used for their detection in human fluids. Using the esterase-2 activity, coupled with a fluorescence inhibition assay, we are able to detect very low concentration levels of diethyl (4-nitrophenyl) phosphate (paraoxon) in the range of the femtomole (fmol). Method robustness tests indicate the stability of esterase-2 in a diluted solution of 4% human urine, and we are able to accurately determine concentration levels of paraoxon in the range from 0.1 to 2 picomoles (pmol). The system sensitivity for OP detection is calculated at 524 ± 14.15 fmol of paraoxon recognized at 10% of inhibition, with an estimated limit of quantification of 262 ± 8.12 pmol mL−1. These values are comparable with the most recent analysis methods based on mass spectrometry carried out on human samples for pesticide detection. This research represents a starting point to develop cheap and fast testing methods for a rapid screening of toxic substances in human samples.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by MDPI
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  • 4
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    Resistance of Two Mediterranean Cold-Water Coral Species to Low-pH Conditions (2013)
    MDPI
    In:  Water, 6 (1). pp. 59-67.
    Details
    Publication Date: 2017-06-19
    Description: Deep-water ecosystems are characterized by relatively low carbonate concentration values and, due to ocean acidification (OA), these habitats might be among the first to be exposed to undersaturated conditions in the forthcoming years. However, until now, very few studies have been conducted to test how cold-water coral (CWC) species react to such changes in the seawater chemistry. The present work aims to investigate the mid-term effect of decreased pH on calcification of the two branching CWC species most widely distributed in the Mediterranean, Lophelia pertusa and Madrepora oculata. No significant effects were observed in the skeletal growth rate, microdensity and porosity of both species after 6 months of exposure. However, while the calcification rate of M. oculata was similar for all colony fragments, a heterogeneous skeletal growth pattern was observed in L. pertusa, the younger nubbins showing higher growth rates than the older ones. A higher energy demand is expected in these young, fast-growing fragments and, therefore, a reduction in calcification might be noticed earlier during long-term exposure to acidified conditions.
    Type: Article , PeerReviewed
    Format: text
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  • 5
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    Understanding the Origin and Mixing of Deep Fluids in Shallow Aquifers and Possible Implications for Crustal Deformation Studies: San Vittorino Plain, Central Apennines (2021)
    MDPI
    Details
    Publication Date: 2021-12-03
    Description: Expanding knowledge about the origin and mixing of deep fluids and the water–rock–gas interactions in aquifer systems can represent an improvement in the comprehension of crustal deformation processes. An analysis of the deep and meteoric fluid contributions to a regional groundwater circulation model in an active seismic area has been carried out. We performed two hydrogeochemical screenings of 15 springs in the San Vittorino Plain (central Italy). Furthermore, we updated the San Vittorino Plain structural setting with a new geological map and cross-sections, highlighting how and where the aquifers are intersected by faults. The application of Na-Li geothermometers, coupled with trace element and gas analyses, agrees in attributing the highest temperatures (〉150 C), the greatest enrichments in Li (124.3 ppb) and Cs (〉5 ppb), and traces of mantle-derived He (1–2%) to springs located in correspondence with high-angle faults (i.e., S5, S11, S13, and S15). This evidence points out the role of faults acting as vehicles for deep fluids into regional carbonate aquifers. These results highlight the criteria for identifying the most suitable sites for monitoring variations in groundwater geochemistry due to the uprising of deep fluids modulated by fault activity to be further correlated with crustal deformation and possibly with seismicity.
    Description: Published
    Description: 1353
    Description: 9T. Geochimica dei fluidi applicata allo studio e al monitoraggio di aree sismiche
    Description: JCR Journal
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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