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  • 1
    Publication Date: 2014-12-11
    Description: Velocity measurements were performed in the draft tube cone of a 1:5.1 scaled model of the Tokke hydropower plant, Norway; also known as the Francis-99 model. Results from the laser Doppler anemometry measurements undertaken at three operating points will be used as validation data for an upcoming workshop on the state of the art of Francis turbine numerical simulation. With the turbine operating at the best efficiency point, a sensitivity analysis of the flow parameters head, flow rate and runner rotational speed shows that the effects on the dimensionless velocity profiles are small as long as n ED and Q ED are held constant. The results indicate a well-functioning turbine at the best efficiency point and high load. At the part load operating point, a vortex breakdown occurs which distorts the velocity profiles and significantly lowers the turbine's hydraulic efficiency. Frequency spectrums of each LDA signal at part load reveals a peak which is asynchronou...
    Print ISSN: 1755-1307
    Electronic ISSN: 1755-1315
    Topics: Geography , Geosciences , Physics
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  • 2
    Publication Date: 2014-05-16
    Description: Mice display robust, stereotyped behaviours towards pups: virgin males typically attack pups, whereas virgin females and sexually experienced males and females display parental care. Here we show that virgin males genetically impaired in vomeronasal sensing do not attack pups and are parental. Furthermore, we uncover a subset of galanin-expressing neurons in the medial preoptic area (MPOA) that are specifically activated during male and female parenting, and a different subpopulation that is activated during mating. Genetic ablation of MPOA galanin neurons results in marked impairment of parental responses in males and females and affects male mating. Optogenetic activation of these neurons in virgin males suppresses inter-male and pup-directed aggression and induces pup grooming. Thus, MPOA galanin neurons emerge as an essential regulatory node of male and female parenting behaviour and other social responses. These results provide an entry point to a circuit-level dissection of parental behaviour and its modulation by social experience.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105201/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105201/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wu, Zheng -- Autry, Anita E -- Bergan, Joseph F -- Watabe-Uchida, Mitsuko -- Dulac, Catherine G -- F32 DC010089/DC/NIDCD NIH HHS/ -- R01 DC003903/DC/NIDCD NIH HHS/ -- R01 DC009019/DC/NIDCD NIH HHS/ -- R01 DC013087/DC/NIDCD NIH HHS/ -- Howard Hughes Medical Institute/ -- England -- Nature. 2014 May 15;509(7500):325-30. doi: 10.1038/nature13307.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute, Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA. ; Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24828191" target="_blank"〉PubMed〈/a〉
    Keywords: Aggression/physiology ; Animals ; Copulation ; Female ; Galanin/deficiency/genetics/*metabolism ; Grooming/physiology ; Male ; Maternal Behavior/*physiology ; Mice ; Neurons/*metabolism ; Optogenetics ; Paternal Behavior/*physiology ; Pheromones/analysis ; Preoptic Area/*cytology/metabolism ; TRPC Cation Channels/deficiency/genetics ; Vomeronasal Organ/physiology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2016-12-13
    Description: Francis-99 is a set of workshop aiming to determine the state of the art of high head model Francis turbine simulations (flow and structure) under steady and transient operating conditions as well as to promote their development and knowledge dissemination openly. The first workshop (Trondheim, 2014) was concerned with steady state operation. The second workshop will focus on transient operations such as load variation and start-stop. In the present work, 2-D particle image velocimetry (PIV) with synchronized pressure measurements performed in the draft tube cone of the Francis-99 test case during load rejection is presented. Pressure sensors were mounted in the vaneless space and draft tube cone to estimate the instantaneous pressure fluctuations while operating the turbine from the best efficiency point (9.8°) to part load (6.7°) with the presence of a rotating vortex rope (RVR). The time-resolved velocity and pressure data are presented in this paper showing the transition in...
    Print ISSN: 1755-1307
    Electronic ISSN: 1755-1315
    Topics: Geography , Geosciences , Physics
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  • 4
    Publication Date: 2016-12-14
    Description: Francis-99 is a set of workshops aiming to determine the state of the art of high head Francis turbine simulations (flow and structure) under steady and transient operating conditions as well as promote their development and knowledge dissemination openly. The first workshop (Trondheim, 2014) focused on steady state conditions. Some concerns were raised regarding uncertainty in the measurements, mainly that there was no clear vortex rope at the Part Load (PL) condition, and that the flow exhibited relatively large asymmetry. The present paper addresses these concerns in order to ensure the quality of the data presented in further workshops. To answer some of these questions, a new set of measurements were performed on the Francis- 99 model at Waterpower Laboratory at the Norwegian University of Science and Technology (NTNU). In addition to PL, two other operating conditions were considered, for further use in transient measurements, Best Efficiency (BEP) and High Load (HL...
    Print ISSN: 1755-1307
    Electronic ISSN: 1755-1315
    Topics: Geography , Geosciences , Physics
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