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  • 1
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    Nuclear p27 Expression Confers a Favorable Outcome for Nasopharyngeal Carcinoma Patients (2013)
    Hindawi
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    Publication Date: 2013-01-01
    Description: Objective. The purpose of the present study is to explore the correlation between nuclear expression of cyclin-dependent kinase inhibitor 1B (p27) and clinicopathologic features in nasopharyngeal carcinoma (NPC), including patient survival.Methods. Immunohistochemistry was used to examine the expression of p27 in 130 primary NPC tissues. The relationship between the levels of p27 expression and clinicopathologic characteristics was analyzed. Survival curves were plotted using the Kaplan-Meier method and compared using the log-rank test. The significance of various survival variables was analyzed using multivariate Cox proportional hazards model.Results. p27 was expressed in both nuclear and cytoplasmic compartments. Nuclear expression of p27 was inversely correlated with T classification and clinical stage. Patients with nuclear p27 expression had better overall survival rates than those without nuclear expression of p27. Further, we observed that nuclear expression of p27 was positively associated with survival time of NPC patients not only in N0-1 and M0 classifications but also in radiotherapy and chemotherapy treatment groups. Finally, we found that nuclear expression of p27 was not an independent prognostic factor for patients with NPC.Conclusions. Our findings hint that nuclear expression of p27 is a potentially favorable factor in the progression and prognosis of NPC.
    Print ISSN: 0278-0240
    Electronic ISSN: 1875-8630
    Topics: Biology , Chemistry and Pharmacology
    Published by Hindawi
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  • 2
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    On the Thermodynamic Properties of the Spinless Duffin-Kemmer-Petiau Oscillator in Noncommutative Plane (2015)
    Hindawi
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    Publication Date: 2015-10-23
    Description: The Duffin-Kemmer-Petiau oscillator for spin 0 particle in noncommutative plane is analyzed and the energy eigenvalue of the system is obtained by employing the functional analysis method. Furthermore, the thermodynamic properties of the noncommutative DKP oscillator are investigated via numerical method and the influence of noncommutative space on thermodynamic functions is also discussed. We show that the energy spectrum and corresponding thermodynamic functions of the considered physical systems depend explicitly on the noncommutative parameter which characterizes the noncommutativity of the space.
    Print ISSN: 1687-7357
    Electronic ISSN: 1687-7365
    Topics: Physics
    Published by Hindawi
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  • 3
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    Energy-Efficient Dual-Iteration Power Allocation for Two-Phase Relay System with Massive Antennas (2014)
    Hindawi
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    Publication Date: 2014-05-06
    Description: This paper considers the scenario where multiple source nodes communicate with multiple destination nodes simultaneously with the aid of an amplify-and-forward relay equipped with massive antennas. In order to achieve optimal energy efficiency (EE) of the entire relay system, this paper investigates the power allocation problem for the multiple pairs of nodes at both the source nodes and the relay node, where the relay employs the backward and forward zero-forcing filters. Since the EE optimization problem cannot be solved analytically, we propose a two-phase power allocation method. Given power allocation of one phase, the optimal power allocation is derived for the other phase. Furthermore, two dual-iteration power allocation (DIPA) algorithms with performance approaching that of optimal EE are developed based on the instantaneous and statistic channel state information, respectively. Numerical results show that the proposed DIPA algorithms can greatly improve EE while guaranteeing spectrum efficiency (SE) when compared with the equal power allocation algorithm. Moreover, both algorithms suggest that deploying a rational number of antennas at the relay node and multiplexing a reasonable number of node pairs can improve on the EE and SE.
    Print ISSN: 1687-5869
    Electronic ISSN: 1687-5877
    Topics: Electrical Engineering, Measurement and Control Technology
    Published by Hindawi
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  • 4
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    Detection of Moving Objects with Fuzzy Color Coherence Vector (2014)
    Hindawi
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    Publication Date: 2014-08-14
    Description: Background subtraction is a popular method for detecting foreground that is widely adopted as the fundamental processing for advanced applications such as tracking and surveillance. Color coherence vector (CCV) includes both the color distribution information (histogram) and the local spatial relationship information of colors. So it overcomes the weakness of the conventional color histogram for the representation of an object. In this paper, we introduce a fuzzy color coherence vector (FCCV) based background subtraction method. After applying the fuzzy c-means clustering to color coherence subvectors and color incoherence subvectors, we develop a region-based fuzzy statistical feature for each pixel based on the fuzzy membership matrices. The features are extracted from consecutive frames to build the background model and detect the moving objects. The experimental results demonstrate the effectiveness of the proposed approach.
    Print ISSN: 1024-123X
    Electronic ISSN: 1563-5147
    Topics: Mathematics , Technology
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  • 5
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    Genes, Vol. 10, Pages 246: The Interaction between Sex and Hyperlipidemia on Gout Risk Is Modulated by HLA-B Polymorphic Variants in Adult Taiwanese (2019)
    MDPI
    In: Genes
    Details
    Publication Date: 2019
    Description: The effects of genetic variants on the interaction between hyperlipidemia and sex have not been investigated among gout patients in Taiwan. Using Taiwan Biobank and the National Health Insurance Research Database (NHIRD), we examined hyperlipidemia, sex, and their relationship with gout among Taiwanese adults with the human leukocyte antigen B (HLA-B) genetic variants. Hyperlipidemia was present in 1437 patients with gout. Sex and hyperlipidemia had significant associations on gout risk, with hyperlipidemia showing a relatively stronger effect. Gout was present in men, with an odds ratio (OR) of 1.945 (95% confidence interval (CI) 1.568–2.411) compared to women, and in hyperlipidemic (OR = 4.032; 95% CI: 3.581–4.540) compared to non-hyperlipidemic patients. The interaction of sex and hyperlipidemia was significant for rs2523608 GG (p = 0.0402) and rs4713518 AA (p = 0.0003) genotypes. After stratification, hyperlipidemia remained a risk factor in women (OR = 4.735, 95% CI: 3.375–6.643) and men (OR = 3.640, 95% CI: 2.916–4.544) with rs2523608 GG genotype. The odds ratio in hyperlipidemic women and men with rs4713518 AA genotype was 7.454 (95% CI 5.103–10.888) and 3.585 (95% CI 2.854–4.503), respectively. Our study indicates that hyperlipidemia-sex interactions exist for gout risk in Taiwanese adults with rs2523608 GG and rs4713518 AA genotypes.
    Electronic ISSN: 2073-4425
    Topics: Biology
    Published by MDPI
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  • 6
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    IJERPH, Vol. 16, Pages 3240: Socioeconomic Inequalities in the HIV Testing during Antenatal Care in Vietnamese Women (2019)
    MDPI
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    Publication Date: 2019
    Description: Although HIV (human immunodeficiency virus) testing for all women has been promoted by Vietnam’s Ministry of Health since 2000, test acceptance rates in this country were reported to be less than 30% in the community. This country has been facing the barriers to approach the national services towards transmission prevention from mother to child including HIV testing during antenatal care (ANC) towards mothers. Here, we aim to assess the socioeconomic inequalities in HIV testing during ANC among Vietnamese women. This study used available data from the Vietnam Multiple Indicator Cluster Survey 2014. Overall, the prevalence of HIV testing during antenatal care was 30% and the concentrate index (CCI) was 0.1926. There was significant inequality between women classified as poor and rich, and when stratified by social characteristics, inequality was found in women aged 15–49 years (CCI: 0.4), living in rural areas (CCI: 0.3), belonging to ethnic minorities (CCI: 0.5) and having primary or less education (CCI: 0.4). In the multivariate logistic regression analysis, ethnicity and socioeconomic status were significant factors associated with HIV testing during ANC. We found the prevalence of HIV testing during ANC was low, and its inequalities were associated with age, living area, ethnicity, education, and economic status.
    Print ISSN: 1661-7827
    Electronic ISSN: 1660-4601
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Published by MDPI
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  • 7
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    Genes, Vol. 10, Pages 820: The Complete Mitogenome of Pyrrhocoris tibialis (Hemiptera: Pyrrhocoridae) and Phylogenetic Implications (2019)
    MDPI
    In: Genes
    Details
    Publication Date: 2019
    Description: We determined the complete mitogenome of Pyrrhocoris tibialis (Hemiptera: Heteroptera: Pyrrhocoridae) to better understand the diversity and phylogeny within Pentatomomorpha, which is the second largest infra-order of Heteroptera. Gene content, gene arrangement, nucleotide composition, codon usage, ribosomal RNA (rRNA) structures, and sequences of the mitochondrial transcription termination factor were well conserved in Pyrrhocoroidea. Different protein-coding genes have been subject to different evolutionary rates correlated with the G + C content. The size of control regions (CRs) was highly variable among mitogenomes of three sequenced Pyrrhocoroidea species, with the P. tibialis CR being the largest. All the transfer RNA genes found in Pyrrhocoroidea had the typical clover leaf secondary structure, except for trnS1 (AGN), which lacked the dihydrouridine arm and possessed an unusual anticodon stem (9 bp vs. the normal 5 bp). A total of three different phylogenetic relationships among the five super-families of Pentatomomorpha were obtained using three analytical methods (MrBayes and RAxML under site-homogeneous models and PhyloBayes under a site-heterogeneous CAT + GTR model) and two mitogenomic datasets (nucleotides and amino acids). The tree topology test using seven methods statistically supported a phylogeny of (Aradoidea + (Pentatomoidea + (Lygaeoidea + (Pyrrhocoroidea + Coreoidea)))) as the best topology, as recognized by both RAxML and MrBayes based on the two datasets.
    Electronic ISSN: 2073-4425
    Topics: Biology
    Published by MDPI
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  • 8
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    Sensors, Vol. 19, Pages 4923: Precoding Design for Energy Efficiency Maximization in MIMO Half-Duplex Wireless Sensor Networks with SWIPT (2019)
    MDPI
    In: Sensors
    Details
    Publication Date: 2019
    Description: This paper explores the energy efficiency (EE) maximization problem in single-hop multiple-input multiple-output (MIMO) half-duplex wireless sensor networks (WSNs) with simultaneous wireless information and power transfer (SWIPT). Such an energy efficiency maximization problem is considered in two different scenarios, in which the number of energy-harvesting (EH) sensor nodes are different. In the scenario where the single energy-harvesting sensor node is applied, the modeled network consists of two multiple-antenna transceivers, of which the energy-constrained energy-harvesting sensor node harvests energy from the signals transmitted from the source by a power splitting (PS) scheme. In the scenario of multiple EH sensor nodes, K energy-constrained sensor nodes are applied and the same quantity of antennas are equiped on each of them. The optimization problem is formulated to maximize the energy efficiency by jointly designing the transceivers’ precoding matrices and the PS factor of the energy-harvesting sensor node. The considered constraints are the required harvested energy, the transmission power limit and the requirement on the data rate. The joint design of the precoding matrices and the PS factor can be formulated as an optimization problem, which can be transformed into two sub-problems. An alternating algorithm based on Dinkelbach is proposed to solve the two sub-problems. The convergence of the proposed alternating algorithm, the solution optimality and the computational complexity are analyzed in the paper. Simulation results demonstrate the convergence and effectiveness of our proposed algorithm for realizing the maximum energy efficiency.
    Electronic ISSN: 1424-8220
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Published by MDPI
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  • 9
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    Production Rate Analysis of Fractured Horizontal Well considering Multitransport Mechanisms in Shale Gas Reservoir (2018)
    Hindawi
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    Publication Date: 2018-10-18
    Description: Shale gas reservoir has been aggressively exploited around the world, which has complex pore structure with multiple transport mechanisms according to the reservoir characteristics. In this paper, a new comprehensive mathematical model is established to analyze the production performance of multiple fractured horizontal well (MFHW) in box-shaped shale gas reservoir considering multiscaled flow mechanisms (ad/desorption and Fick diffusion). In the model, the adsorbed gas is assumed not directly diffused into the natural macrofractures but into the macropores of matrix first and then flows into the natural fractures. The ad/desorption phenomenon of shale gas on the matrix particles is described by a combination of the Langmuir’s isothermal adsorption equation, continuity equation, gas state equation, and the motion equation in matrix system. On the basis of the Green’s function theory, the point source solution is derived under the assumption that gas flow from macropores into natural fractures follows transient interporosity and absorbed gas diffused into macropores from nanopores follows unsteady-state diffusion. The production rate expression of a MFHW producing at constant bottomhole pressure is obtained by using Duhamel’s principle. Moreover, the curves of well production rate and cumulative production vs. time are plotted by Stehfest numerical inversion algorithm and also the effects of influential factors on well production performance are analyzed. The results derived in this paper have significance to the guidance of shale gas reservoir development.
    Print ISSN: 1468-8115
    Electronic ISSN: 1468-8123
    Topics: Geosciences
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  • 10
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    A Numerical Study of Initiation and Migration of Trapped Oil in Capillaries with Noncircular Cross Sections (2019)
    Hindawi
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    Publication Date: 2019-08-08
    Description: To clarify the initiation and migration mechanisms of a discontinuous oil phase in pores, a numerical study was performed to interpret the starting phenomenon and flowing rules of oil trapped in capillaries that have noncircular cross sections. In this study, capillaries with three different cross sections were used to investigate the deformation law of oil and the pressure drop across these microchannels at different displacement velocities by computational fluid dynamics (CFD). The geometrical structure of the microchannels was precisely controlled, and the migration process of the oil, which is too small to be observed by direct experimentation, was assessed and quantitatively analyzed. By analyzing the shape of the trapped oil after reaching a steady state at different velocities, the nonstart and start conditions could be distinguished and the accuracy of the numerical method was verified by a comparison with an analytical method (the MS-P method). Two aspects of oil migration in noncircular microchannels were observed in combination with previous studies: there is a driving force on the cross section of the oil drop and a viscous force at the oil-water interface in the corners, and the more irregular the pore section is, the more easily the trapped oil will migrate. Additionally, the influence of the microchannel cross-sectional shape on the non-Darcy flow of a discontinuous oil phase was clarified. It can be concluded that the presence of the non-Darcy flow in pores arises because trapped oil, as a discontinuous phase, cannot be separated from the capillary wall without reaching critical velocity.
    Print ISSN: 1468-8115
    Electronic ISSN: 1468-8123
    Topics: Geosciences
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