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  • Books  (61)
  • Cham :Springer International Publishing :  (45)
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  • 1
    Keywords: Physical geography. ; Environment. ; Economic development. ; Environmental management. ; Physical Geography. ; Environmental Sciences. ; Development Studies. ; Environmental Management.
    Description / Table of Contents: 1. Delta challenges and trade-offs from the Holocene to the Anthropocene -- 2. Ganges-Brahmaputra-Meghna Delta, Bangladesh and India: A transnational mega-delta -- 3. The Mahanadi Delta: A rapidly developing delta in India -- 4. The Volta Delta, Ghana: challenges in an African setting -- 5. Fluvial sediment supply and relative sea-level rise -- 6. Hotspots of present and future risk within deltas; hazards, exposure and vulnerability -- 7. Where people live and move in deltas -- 8. Delta economics and sustainability -- 9. Adapting to change: People and policies -- 10. Choices: Future trade-offs and plausible pathways -- 11. Sustainable deltas in the Anthropocene.
    Abstract: The Anthropocene is the human-dominated modern era that has accelerated social, environmental and climate change across the world in the last few decades. This open access book examines the challenges the Anthropocene presents to the sustainable management of deltas, both the many threats as well as the opportunities. In the world’s deltas the Anthropocene is manifest in major land use change, the damming of rivers, the engineering of coasts and the growth of some of the world’s largest megacities; deltas are home to one in twelve of all people in the world. The book explores bio-physical and social dynamics and makes clear adaptation choices and trade-offs that underpin policy and governance processes, including visionary delta management plans. It details new analysis to illustrate these challenges, based on three significant and contrasting deltas: the Ganges-Brahmaputra-Meghna, Mahanadi and Volta. This multi-disciplinary, policy-orientated volume is strongly aligned to the United Nation’s Sustainable Development Goals as delta populations often experience extremes of poverty, gender and structural inequality, variable levels of health and well-being, while being vulnerable to extreme and systematic climate change. Robert J Nicholls is Professor of Coastal Engineering within Engineering and Physical Sciences at the University of Southampton, UK. He has contributed to a wide range of influential national and international publications including the IPCC Assessment Reports. W Neil Adger is Professor of Human Geography at the University of Exeter, UK. His research examines demographic, political economy, public health and well-being aspects of the Anthropocene. Craig W Hutton is Professor of Sustainability Science within Geography and Environment at the University of Southampton, UK. His research focuses on spatial analysis of vulnerability and the incorporation of sustainable management, policy and governance into decision-making processes. Susan E Hanson is Research Fellow within Engineering and Physical Sciences at the University of Southampton, UK. She specializes in coastal vulnerability and management, particularly as a consequence of climate change.
    Type of Medium: Online Resource
    Pages: XXXIII, 282 p. 55 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030235178
    DDC: 910.02
    Language: English
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  • 2
    Call number: SR 91.1609(27/2)
    In: Mededelingen
    Type of Medium: Series available for loan
    Pages: S. 42-79
    Series Statement: Mededelingen / Rijks Geologische Dienst N.S., vol.27, no.2
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 3
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    DDC: 615
    Language: English
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  • 4
    Keywords: Biodiversity. ; Biotic communities. ; Conservation biology. ; Ecology . ; Vertebrates. ; Invertebrates. ; Biodiversity. ; Ecosystems. ; Conservation Biology. ; Vertebrate Zoology. ; Invertebrate Zoology.
    Description / Table of Contents: 1.1 General Introduction Principal -- 2. Zoloogical Groups -- 2.1 Arachnids -- 2.2 Insects: Migrants, endemics, and old to new pests -- 2.3 Freshwater decapod crustaceans: the challenges of documenting and preserving a very diverse fauna -- 2.4 Mexican molluscs: In the process of a 'silent extinction' -- 2.5 Amphibians and reptiles -- 2.6 Anthropocene impacts on the Mexican freshwater fish fauna -- 2.7 Mexican avifaunas of the Anthropocene -- 2.8 Marine birds -- 2.9 Terrestrial mammals -- 2.10 Marine mammals -- 2.11Mexican bats: conservation challenges in the Anthropocene -- 3. Ecosytems -- 3.1 The impact of the growth of urban environments on Mexican fauna -- 3.2 Anchialine fauna of the Yucatan Peninsula -- 3.3 Semi-terrestrial and aquatic invertebrates and fish in mangroves in México -- 3.4 Defaunation of Mexican tropical forests3.5 Mezcal boom and extinction debts in Mexican arid ecosystems -- 3.6 Deep sea life -- 3.7 The importance of agroecosystems for the Mexican fauna -- 3.8 The salamanders of the Mexican cloud forest -- 3.9 Human effects on caves in Mexico -- 3.10 Fauna of lakes and rivers -- 3.11 Coral reef faunal assemblages in the Mexican Caribbean: assessing the cryptic biodiversity -- 4 Processes -- 4.1 Contemporary climate change impacts on Mexican fauna -- 4.2 Invasive alien species of invertebrates and fishes introduced to Mexican freshwater systems -- 4.3 Are marine fisheries sustainable? -- 4.4 Pest dynamics in Mexican forests -- 4.5 Pollination by wild and managed animal vectors -- 4.6 Social participation strategies for the conservation of Mexican fauna -- 4.7 Citizen science for deep ocean biodiversity: a crowdsourcing tool in support of conservation -- 4.8 Legal actions for the conservation of fauna.
    Abstract: This contributed volume presents an analysis of the current conservation status of major faunal groups in Mexico. The chapters describe a prognosis of future challenges, and also explore the expanding threats inherent in the Anthropocene within the context of the unique physical, biological and cultural aspects of the nation. Covering 27 chapters, and written by Mexican and international authors, this book analyzes a wide range of vertebrate and invertebrate animal taxa, their ecosystems and the critical processes related to their present conservation status. This volume is an important reference material for researchers, conservationists and students interested in the biological and ecological processes shaping the Mexican fauna.
    Type of Medium: Online Resource
    Pages: XVII, 597 p. 50 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031172779
    DDC: 333.95
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agriculture. ; Agriculture.
    Description / Table of Contents: Chapter 1 The Role of Skepticism in Science? -- Chapter 2 Warnings for Skeptics -- Chapter 3 Photosynthesis -- Chapter 4 Seed Number -- Chapter 5 Nitrogen Use Efficiency -- Chapter 6 Water Use Efficiency -- Chapter 7 Water Loss -- Chapter 8 Unconfirmed Field Observations (UFOs).
    Abstract: Global food production and climate change among other concerns are societal issues that require major research input from crop science. While suggestions are abundant on how crop science can help to resolve these issues, many of the suggestions come from people who are not actually familiar with the challenges and requirements to modify crop plants grown under field conditions to achieve the necessary improvements. Efforts to alter a gene or even several genes have very rarely proven successful in having impact on crop production under realistic field conditions. This lack of success has not been addressed head on. This book serves as a reminder to crop scientists and others that open, clear-minded assessments of the entirety of evidence concerning a hypothesis is required before making claims of possible increases in crop performance. This attitude of skepticism is not a negative attitude but rather an employment of the cornerstone of scientific investigation based on formation and evaluation of hypotheses. Skeptical analyses are to be presented in the book on some of the common suggestions for improving crop plants. The six specific topics to be addressed are photosynthesis, seed number, nitrogen use efficiency, water use efficiency, crop water loss, and unconfirmed field observations. Each of the topics in this book, will first be reviewed to present the origins of the popular assumptions about how specific plant modification will result in improved crop performance. The review of the background information will be followed by an examination of the evidence, logic, and predicted outcomes for the assumed benefits of the modifications. Finally, each chapter will offer novel, alternate approaches to plant modification that have documented support for positively impacting crop performance. The book will not be written in specialized, detail language but offer access for those with a wide range of interests in options for increasing crop production in the future. The goal of the book is to provide information that is useful to those with interests ranging from climatologist to food-oriented sociologists. Of course, the topics covered will be of direct interest to those studying plant sciences, particularly crop scientists. The hope is to challenge a reader to re-examine some of her/his assumptions about crop improvement and approach the topic with a renewed practice of skepticism in formulating and evaluating hypotheses. .
    Type of Medium: Online Resource
    Pages: VI, 66 p. 32 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031144141
    Series Statement: SpringerBriefs in Agriculture,
    DDC: 630
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Evolution (Biology). ; Paleontology . ; Anatomy, Comparative. ; Vertebrates. ; Animal migration. ; Physiology. ; Evolutionary Biology. ; Paleontology. ; Animal Anatomy. ; Vertebrate Zoology. ; Animal Migration. ; Animal Physiology.
    Description / Table of Contents: 1. Introduction to the morphology, development, and ecology of feathers -- 2. Molecular and cellular mechanisms of feather development provide a basis for diverse evolution of feather forms -- 3. The origin of birds: current consensus, controversy, and the occurrence of feathers -- 4. Integumentary structures in Kulindadromeus zabaikalicus, a basal neornithischian dinosaur from the Jurassic of Siberia -- 5. Filamentous integuments in non-avialan theropods and their kin: advances and future perspectives for understanding the evolution of feathers -- 6. Two of a feather: A comparison of the preserved integument in the juvenile theropod dinosaurs Sciurumimus and Juravenator from the Kimmeridgian Torleite Formation of southern Germany -- 7. Feather evolution in Pennaraptora -- 8. The feathers of the Jurassic Urvogel Archaeopteryx -- 9. The plumage of basal birds -- 10. A morphological review of the enigmatic elongated tail feathers of stem birds -- 11. Review on color patterns of fossil feathers -- 12. On the ancestry of feathers in Mesozoic dinosaurs.
    Abstract: Feathers are one of the most unique characteristics of modern birds and represent the most complex and colourful type of skin derivate within vertebrates, while also fulfilling various biological roles, including flight, thermal insulation, display, and sensory function. For years it was generally assumed that the origin of flight was the main driving force for the evolution of feathers. However, various discoveries of dinosaur species with filamentous body coverings, made over the past 20 years, have fundamentally challenged this idea and produced new evolutionary scenarios for the origin of feathers. This book is devoted to the origin and evolution of feathers, and highlights the impact of palaeontology on this research field by reviewing a number of spectacular fossil discoveries that document the increasing morphological complexity along the evolutionary path to modern birds. Also featuring chapters on fossil feather colours, feather development and its genetic control, the book offers a timely and comprehensive overview of this popular research topic. .
    Type of Medium: Online Resource
    Pages: VIII, 243 p. 80 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030272234
    Series Statement: Fascinating Life Sciences,
    DDC: 576.8
    Language: English
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  • 7
    Keywords: Food science. ; Chemistry. ; Food Science. ; Chemistry.
    Description / Table of Contents: Section 1: Introduction -- 1. Introduction: Career Preparation for the Food & Beverage Industry -- 2. The Equilibrium of Life-Career Planning -- 3. First Jobs for Food Science -- Section 2: The undergraduate student experience -- 4. Making the Most of Your Undergraduate Experience -- 5. Campus Career Services and Centers -- 6. Professionalism and Leadership -- 7. Is Food Science Right For Me? The Transfer Experience -- 8. The Decision to Pursue an Internship -- 9. IFT Student Association -- Section 3: A successful industry career -- 10. Finding and negotiating a job -- 11. Employer expectations/Managing corporate life -- 12. Could a small company be for you? -- 13. A successful industry career or Making your way in a company -- Section 4: Careers with a degree in food science -- 14. Quality -- 15. Production management -- 16. Product development -- 17. Technical sales -- 18. R&D -- 19. Regulatory and food law -- 20. Careers in Traceability -- 21. Using food science in special interest groups -- 22. Food for Good: Leveraging Food Science to Feed the World -- 23. Careers that combine Culinary and Food Science -- 24. Entrepreneurship and Consulting: Taking a Different Path -- 25. Careers in Sensory Science -- 26. Food Science in Community-Based Food Systems -- 27. Working for a Startup Company -- 28. Careers in Sustainability -- 29. A Career in Management -- Section 5: The graduate student experience -- 30. Is grad school right for me? -- 31. Finding and getting into the right grad program -- 32. The transition from undergraduate to graduate student -- 33. Faculty expectations of graduate students.
    Abstract: Careers in Food Science provides detailed guidelines for students and new employees in the food industry to ensure a successful start to their career. Every step towards a rewarding career in this rapidly evolving industry is covered, from which classes to take in college and which degrees to earn, to internships, and finally how to land, and keep, the first job. This book also provides day-to-day examples of what to expect from the many jobs available to help students decide what to do and where to go. This second edition includes nine new chapters covering research chefs, food systems, social justice, food waste, start-ups, sustainability, and management. Several new authors offer fresh perspectives. Provides detailed guidelines for students as well as new employees in food industry; Includes perspectives from school years through how to succeed at new job; Written by individuals who have just gone through that experience or who are working in that particular sector.
    Type of Medium: Online Resource
    Pages: XII, 411 p. 5 illus., 1 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031143533
    DDC: 641.3
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Zoology. ; Biodiversity. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Ecology. ; Zoology. ; Biodiversity.
    Description / Table of Contents: Introduction: Christopher Clark and Ellen Garland -- Ch 1: Overview. Christopher Clark -- Ch. 2: Anatomy and physiology. Joy Reidenberg -- Ch. 3: Movement, Residency & Migration. Alex Zerbini and Sue Moore,- Ch. 4: Feeding strategies. Ari Friedlaender -- Ch. 5: Molecular genetics. Emma Carroll -- Ch. 6: Social organization. Peter Tyack -- Ch. 7: Ethological and bioacoustic variability. Christopher Clark -- Ch. 8: Baleen whale culture. Ellen Garland and Emma Carroll -- Ch. 9: Blue whale – Global diversity & behavioral variability in a specialist. Ana Sirovic -- Ch. 10: Humpback whale – Global diversity & behavioral plasticity in a court jester. Rebecca Dunlop -- Ch. 11: Humpback whale song - Global diversity & behavioral plasticity in a court jester. Danielle Cholewiak, Sal Cerchio and Ellen Garland -- Ch. 12: Bowhead whale – Acoustic variability in the almost-a-right whale that went north. Kate Stafford -- Ch. 13: Right whales - From north to south, what’s the big difference? Susan Parks -- Ch. 14: Minke Whale – Diversity and variability. Denise Risch -- Ch. 15: Omura’s Whale – An enigma. Sal Cerchio. .
    Abstract: In this book, an international team of leading marine mammal scientists, with a remarkably diverse set of backgrounds and areas of expertise, lead you through a synthesis of current knowledge on baleen whales. Baleen whales are the largest animals ever to have lived on this planet. They also have the lowest and most intense voices on Earth, most likely evolved to take advantage of ocean acoustic transmission conditions so as to be detectable across ocean basins. Some baleen whales can live to be 150-200 years old. They migrate many thousands of kilometers between feeding and breeding areas. They produce songs and calls that serve as behavioral foundations for establishing, maintaining and expanding their cultural identities. To conclude that we know the behavioral limits of these large brained, long-lived animals would be naïve. As baleen whale scientists, we are still beginning to comprehend the enormous complexities and natural histories of these remarkable animals. Today, the fact that whales sing is known throughout much of the world. This awareness started 50 years ago with the publication and popularization of a collection of humpback song recordings that motivated research into baleen whale behavioral ethology. In this book’s chapters, a reader’s experiences will stretch from learning about baleen whale laryngeal anatomy associated with their different voices to learning about the vast ocean areas over which their voices can be heard and the emerging complexities of their culturally defined societies. These are accompanied by chapters on the fundamental ethological contexts of socializing, migrating, and foraging. Two common themes permeate the book. One theme highlights the phenomenal increase in scientific knowledge achieved through technological advancements. The other theme recognizes the impacts of human-made activities on ocean acoustic environments and the resultant influences on the health and survival of individual whales and their populations. Although the book is intentionally ambitious in its scope, as scientists, we fully recognize that baleen whale science is still in its infancy. Many profound revelations await discovery by cohorts of young, multi-talented explorers, some of whom are stretching their wings in this volume and some of whom are reading these scientific stories for the first time.
    Type of Medium: Online Resource
    Pages: XVI, 384 p. 87 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030984496
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    DDC: 577.6
    Language: English
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  • 9
    Keywords: Clinical biochemistry. ; Medical genetics. ; Human physiology. ; Proteins. ; Medical Biochemistry. ; Medical Genetics. ; Human Physiology. ; Proteins.
    Description / Table of Contents: 1. The disease-modifying role of taurine and its therapeutic potential in Coronavirus Disease 2019 (COVID-19) -- 2. Examination of taurine chloramine and taurine on LPS-induced acute pulmonary inflammation in mice -- 3. Synergism between taurine and dexamethasone in anti-inflammatory response in LPS-activated macrophages -- 4. Regulation of CXCR4 expression by taurine in macrophage-like cells -- 5. Taurine chloramine inhibits leukocyte migration by suppressing actin polymerization and extracellular signal regulated kinase -- 6. Taurine alleviates LPS-induced acute lung injury by suppressing TLR-4/NFKB pathway -- 7. Intervention effect of taurine on LPS-induced intestinal mechanical barrier injury in piglets -- 8. Current opinion on the therapeutic capacity of taurine containing halogen derivatives in infectious and inflammatory diseases -- 9. Taurine and N-bromotaurine in topical treatment of psoriasis -- 10. Taurine deficiency in tissues aggravates radiation-induced gastrointestinal syndrome -- 11. Taurine and its anti-cancer functions: In vivo and in vitro study -- 12. Taurine supplementation inhibits the expression of Atrogin-1 and MuRF-1, protein degradation marker genes, in skeletal muscle of C26-induced cachexia mouse model -- 13. Bioavailability of tauropine after oral ingestion in mouse -- 14. Taurine prevents liver injury by reducing oxidative stress and cytochrome c mediated apoptosis in broilers under low temperature -- 15. Effects of taurine on serum indexes of broilers with chronic heat stress -- 16. Antioxidant effect of taurine on chronic heat stressed broilers -- 17. Grading of Japanese diet intakes by 24-hour urine analysis of taurine and soy isoflavones in relation to cardiovascular risks -- 18. Perinatal taurine supplementation preserves the benefits of dynamic exercise training on cardiovascular and metabolic functions and prevents organ damage in adult male exercised rats -- 19. Impaired bile acid synthesis in a taurine-deficient cat model -- 20. Characterization of bone tissue and bone morphology in taurine transporter knockout mice -- 21. Blood taurine dynamics in captive lions: relationship with feed and bile acid composition -- 22. Taurine ameliorates apoptosis via Akt pathway in the kidney of diabetic rats -- 23. Taurine ameliorates oxidative stress in spinal cords of diabetic rats via Keap-Nrf2 signaling -- 24. Assessment of in vitro tests as predictors of the antioxidant effects of insulin, metformin and taurine in the brain of diabetic rats -- 25. Potential binding sites for taurine on the insulin receptor: A molecular docking study -- 26. Dietary protein modulates the efficacy of taurine supplementation on adaptive islet function and morphology in obesity -- 27. Taurine and exercise: Synergistic effects on adipose tissue metabolism and inflammatory processes in obesity -- 28. The taurine conjugated bile acid (TUDCA) normalizes insulin secretion in pancreatic b-cells exposed to fatty acids: Role of mitochondrial metabolism -- 29. Effect of taurine on the regulation of glucose uptake in skeletal muscle -- 30. Differences between physiological and pharmacological actions of taurine -- 31. Taurine and the brain -- 32. Electrophysiological evidence for anti-epileptic property of taurine -- 33. Observation of acupuncture effects on the expression of taurine transporter and taurine in the senescence-accelerated mouse brain: A pilot study -- 34. The regulatory effects of taurine on neurogenesis and apoptosis of neural stem cells in the hippocampus of rats -- 35. Brain-derived neurotrophic factor potentiates entorhinal-dentate but not hippocampus CA1 pathway in adult male rats: A mechanism of taurine-modulated BDNF on learning and memory -- 36. Influences of taurine pharmacodynamics and sex on active avoidance learning and memory -- 37. The effects of dietary taurine-containing jelly supplementation on cognitive function and memory ability of the elderly with subjective cognitive decline -- 38. Effects of dietary taurine-containing jelly supplementation on academic-related characteristics and academic achievement in Korean college entrance examinees: a pilot study -- 39. Improvement in willingness to purchase taurine-containing jelly needs high degrees of interest and preference: focused on Korean college students -- 40. Positive eusocial impacts on ants by taurine derivatives -- 41. Taurine prevents AFB1-induced renal injury by inhibiting oxidative stress and apoptosis -- 42. Taurine-derived compounds produce anxiolytic effects in rats following developmental lead exposure -- 43. Developmental lead exposure in rats causes sex-dependent changes in neurobiological and anxiety-like behaviors that are improved by taurine co-treatment -- 44. In vivo sex-dependent effects of perinatal Pb2+ exposure on pilocarpine-induced seizure susceptibility and taurine neuropharmacology -- 45. Taurine prevents LPS-induced liver injury in weaned piglets.
    Abstract: This volume gathers a selection of original articles and reviews on timely topics about the application of Taurine in human health written by members of the International Taurine Society, including COVID-19, cancer, heart disease, and diabetes, among others. Chapters are written by Taurine experts across the globe in North and South America, Asia, and Europe. A majority of the articles are based on original studies recently carried out in individual laboratories worldwide. The book is divided into eight parts, each covering a unique aspect of Taurine. Each section will highlight new research findings on Taurine and its application in various human systems, including the nervous system, immune system, and cardiovascular system, to combat disease. The first section covers COVID-19, the dominant health event of 2020. Experts will explore and clarify the potential therapeutic effectiveness of Taurine against COVID-19. The volume will promote further research into the application of Taurine in human health, and will be of use to a wide audience, including basic and clinical scientists, pharmaceutical and nutraceutical companies, and libraries. .
    Type of Medium: Online Resource
    Pages: XII, 518 p. 181 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030933371
    Series Statement: Advances in Experimental Medicine and Biology, 1370
    DDC: 612.015
    Language: English
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  • 10
    Keywords: Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy.
    Description / Table of Contents: Dedication -- Preface.-The carbonic anhydrases in health and disease -- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets -- Targeting carbonic anhydrases in vascular and pulmonary disease -- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema -- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders -- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes -- An overview of carbonic anhydrase-related neoplasms -- The carbonic anhydrase IX interactome and the regulation of cancer progression -- Carbonic anhydrase IX: current and emerging therapies -- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents -- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening -- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.
    Abstract: This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.
    Type of Medium: Online Resource
    Pages: XII, 288 p. 38 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030795115
    Series Statement: Progress in Drug Research, 75
    DDC: 615
    Language: English
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