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Digitale Medien

Amino-acids in Nectar and their Evolutionary Significance (1973)

BAKER, H. G. ; BAKER, IRENE

[s.l.] : Nature Publishing Group

Nature 241 (1973), S. 543-545

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] This evidence of concern with amino-acid ingestion by adult insects usually thought of as restricted to a liquid diet suggests that nectar itself should be examined as a potential source. Some comprehensive analyses of honey (which contains additives provided by its makers, the honey T)ees), have ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/241543b0

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2

Unbekannt

Crystal Structure of Methylmalonyl-Coenzyme A Epimerase from P. shermanii (2001)

McCarthy, Andrew A ; Baker, Heather M ; Shewry, Steven C ; [weitere]

Cell Press

In: Structure. 2001; 9(7): 637-646. Published 2001 Jul 01. doi: 10.1016/s0969-2126(01)00622-0.

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Publikationsdatum: 2001-07-01

Print ISSN: 0969-2126

Digitale ISSN: 1878-4186

Thema: Biologie , Medizin

Publiziert von Cell Press

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3

Digitale Medien

Computational redesign of protein-protein interaction specificity (2004)

Kortemme, Tanja ; Joachimiak, Lukasz A ; Bullock, Alex N ; [weitere]

[s.l.] : Nature Publishing Group

Nature structural & molecular biology 11 (2004), S. 371-379

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ISSN: 1545-9985

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] We developed a 'computational second-site suppressor' strategy to redesign specificity at a protein-protein interface and applied it to create new specifically interacting DNase-inhibitor protein pairs. We demonstrate that the designed switch in specificity holds in in vitro binding and functional ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nsmb749

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4

Digitale Medien

Comparative analysis of the genome sequences of Bordetella pertussis , Bordetella parapertussis and Bordetella bronchiseptica (2003)

Sebaihia, Mohammed ; Preston, Andrew ; Murphy, Lee D ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 35 (2003), S. 32-40

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative β-proteobacteria that colonize the respiratory tracts of mammals. B. pertussis is a strict human pathogen of recent evolutionary origin and is the primary etiologic agent of whooping ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1227

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5

Digitale Medien

Communication between ClpX and ClpP during substrate processing and degradation (2004)

Joshi, Shilpa A ; Hersch, Greg L ; Baker, Tania A ; [weitere]

[s.l.] : Nature Publishing Group

Nature structural & molecular biology 11 (2004), S. 404-411

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ISSN: 1545-9985

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] In the ClpXP compartmental protease, ring hexamers of the AAA+ ClpX ATPase bind, denature and then translocate protein substrates into the degradation chamber of the double-ring ClpP14 peptidase. A key question is the extent to which functional communication between ClpX and ClpP occurs and is ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nsmb752

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6

Digitale Medien

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice (2004)

Baker, Darren J ; Jeganathan, Karthik B ; Cameron, J Douglas ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 36 (2004), S. 744-749

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Faithful segregation of replicated chromosomes is essential for maintenance of genetic stability and seems to be monitored by several mitotic checkpoints. Various components of these checkpoints have been identified in mammals, but their physiological relevance is largely unknown. Here we show that ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1382

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7

Digitale Medien

Positional cloning of a novel gene influencing asthma from Chromosome 2q14 (2003)

Allen, Maxine ; Heinzmann, Andrea ; Noguchi, Emiko ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 35 (2003), S. 258-263

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Asthma is a common disease in children and young adults. Four separate reports have linked asthma and related phenotypes to an ill-defined interval between 2q14 and 2q32 (refs. 1–4), and two mouse genome screens have linked bronchial hyper-responsiveness to the region homologous to 2q14 ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng1256

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8

Digitale Medien

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease (2001)

Kwon, Chang-Hyuk ; Zhu, Xiaoyan ; Zhang, Junyuan ; [weitere]

[s.l.] : Nature Publishing Group

Nature genetics 29 (2001), S. 404-411

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ISSN: 1546-1718

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Medizin

Notizen: [Auszug] Somatic inactivation of PTEN occurs in different human tumors including glioblastoma, endometrial carcinoma and prostate carcinoma. Germline mutations in PTEN result in a range of phenotypic abnormalities that occur with variable penetrance, including neurological features such as macrocephaly, ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/ng781

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9

Digitale Medien

Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo (2001)

Nicklin, Stuart A. ; Kaliberova, Lioudmila ; Boatman, Brian G. ; [weitere]

[s.l.] : Nature Publishing Group

Nature biotechnology 19 (2001), S. 838-842

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] The promise of gene therapy for health care will not be realized until gene delivery systems are capable of achieving efficient, cell-specific gene delivery in vivo. Here we describe an adenoviral system for achieving cell-specific transgene expression in pulmonary endothelium. The combination of ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/nbt0901-838

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10

Digitale Medien

Drug discovery—an operating model for a new era (2001)

Myers, Scott ; Baker, Ann

[s.l.] : Nature Publishing Group

Nature biotechnology 19 (2001), S. 727-730

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ISSN: 1546-1696

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Notizen: [Auszug] The quest for innovation and productivity among pharmaceutical companies is about to enter a new phase. Fundamental changes in the drug discovery landscape, including new science, technologies, and organizational tools—as well as continued financial pressure—have created unprecedented ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/90765

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