ALBERT

Beschreibung: A reliable ionospheric specification by empirical models is important to mitigate the effects of the ionosphere on the operations of satellite based positioning and navigation systems. This study evaluates the capability of the International Reference Ionosphere (IRI) and IRI extended to the plasmasphere (IRI-Plas) models in predicting the Total Electron Content (TEC) over stations located in the Southern hemisphere of the African equatorial and low latitude region. TEC derived from Global Positioning System (GPS) measurements were compared with TEC-predicted by both the IRI-Plas 2015 model and the three topside options of the IRI 2012 model [i.e. NeQuick (NeQ), IRI 2001 corrected factor (IRI-01 Corr) and the IRI 2001(IRI-01)]. Generally, the diurnal and the seasonal structures of modeled-TEC follow quite well with the observed-TEC in all the stations, although with some upward and downward offsets observed during the daytime and nighttime. The prediction errors of both models exhibit latitudinal variation and these showed seasonal trends. The values generally decrease with increase in latitude. The TEC data-model divergence of both models is most significant at stations in the equatorial region during the daytime and nighttime. Conversely, both models demonstrate most pronounced convergence during the nighttime at stations outside the equatorial region. The IRI-Plas model, in general, performed better in months and seasons when the three options of the IRI model underestimate TEC. Factors such as the height limitation of the IRI model, the inaccurate predictions of the bottomside and topside electron density profiles were used to explain the data-model discrepancies.

Beschreibung: Properties of raw sawdust of Parkia biglobosa, as a biosorbent for the removal of Acid Blue 161 dye in single, binary, and ternary dye systems with Rhodamine B and Methylene Blue dyes in aqueous solution, were investigated. The sawdust was characterized using Scanning Electron Microscopy, Fourier Transform Infrared spectrophotometry, X-ray diffraction, and pH point of zero charge. Batch adsorption experiments were carried out to determine the equilibrium characteristics, thermodynamics, and kinetics of the sorption processes. The data obtained were subjected to various isotherm and kinetics equations. The results showed that the adsorption processes were described by different isotherm models depending on the composition of the system; they were all spontaneous ( ranges from −0.72 to −5.36 kJ/mol) and endothermic (range of is 11.37–26.31 kJ/mol) and with increased randomness with values of 55.55 and 98.78 J·mol/K for single and ternary systems, respectively. Pseudo-second-order kinetics model gave better fit for all the sorption systems studied irrespective of the differences in composition, with the initial and overall rate constants higher for the mixtures than for the single system (6.76 g·mg−1min−1). The presence of Rhodamine B and Methylene Blue had a synergetic effect on the maximum monolayer capacity of the adsorbent for Acid Blue 161 dye.

Beschreibung: Background: The objectives of the present study were to investigate the efficacy of the mixed culture of Lactobacillus acidophilus (DSM 20242), Bifidobacterium bifidum (DSM 20082) and Lactobacillus helveticus (CK60) in the fermentation of maize and the evaluation of the effect of the fermented meal on the lipid profile of rats. Methods: Rats were randomly assigned to 3 groups and each group placed on a Diet A (high fat diet into which a maize meal fermented with a mixed culture of Lb acidophilus (DSM 20242), B bifidum (DSM 20082) and Lb helveticus (CK 60) was incorporated), B (unfermented high fat diet) or C (commercial rat chow) respectively after the first group of 7 rats randomly selected were sacrificed to obtain the baseline data. Thereafter 7 rats each from the experimental and control groups were sacrificed weekly for 4 weeks and the plasma, erythrocytes, lipoproteins and organs of the rats were assessed for cholesterol, triglyceride and phospholipids. Results: Our results revealed that the mixed culture of Lb acidophilus (DSM 20242), B bifidum (DSM 20082) and Lb helveticus (CK 60) were able to grow and ferment maize meal into 'ogi' of acceptable flavour. In addition to plasma and hepatic hypercholesterolemia and hypertriglyceridemia, phospholipidosis in plasma, as well as cholesterogenesis, triglyceride constipation and phospholipidosis in extra-hepatic tissues characterized the consumption of unfermented hyperlipidemic diets. However, feeding the animals with the fermented maize diet reversed the dyslipidemia. Conclusion: The findings of this study indicate that consumption of mixed culture lactic acid bacteria (Lb acidophilus (DSM 20242), Bifidobacterium bifidum (DSM 20082) and Lb helveticus (CK 60) fermented food results in the inhibition of fat absorption. It also inhibits the activity of HMG CoA reductase. This inhibition may be by feedback inhibition or repression of the transcription of the gene encoding the enzyme via activation of the sterol regulatory element binding protein (SREBP) transcription factor. It is also possible that consumption of fermented food enhances conversion of cholesterol to bile acids by activating cholesterol-7alpha-hydroxylase.

Beschreibung: Cold and immobilization stressors can generate oxidative stress as well as skeletal muscle fatigue. Free radicals cause oxidative degradation of lipids, proteins, nucleic acids, and carbohydrates molecules, thereby compromising cell integrity and function. Quail egg had been described as being very functional biochemically, due to the essential biomolecules it contains in very regulated quantity. This study was aimed for evaluating the dietary effect of the egg on lipid profile parameters on selected tissues. The antilipidemic properties of the egg yolk and albumen and poultry (layers) feed were determined in selected tissues in male albino rats assaulted with cold immobilization stress induced on them at 4°C for 2 hours, while diazepam was used as standard antistress drug. Antilipidemic activities were evaluated by lipid profile modulation (HDL, LDL, TRIG., and T-CHOL.). Quantitative and qualitative analyses of fatty acids profile of the yolk hexane-extract were determined by Gas Chromatography and Mass Spectrophotometry (GC-MS). The ameliorative impacts of diazepam (2.5 and 5.0 mg/mL/kg BW), yolk (5 and 10 mL/kg BW), albumen (5 and 10 mL/kg BW), and the feed (5–10 mg/kg BW) were competitively () specific for each of the tissues. The result of the study suggested yolk and albumen of quail egg and poultry feed as antistress agents as well as lipid modulators.

Beschreibung: We have used Total Electron Content (TEC) derived from dual frequency GPS receivers to study magnetically quiet and storm time variations of the ionosphere at Ilorin(8.47°N, 4.68°E), an equatorial station in the Africa sector. Four years (2009-2012) data were used for the study. The result on the quiet-time variation of the ionosphere showed that diurnal variation of TEC is not symmetrical about noon. This is a departure from a typical Chapman variation. Daytime maximum occurred after local noon (13-16 LT) for all the seasons and at all solar activity levels considered. A significant effect of solar activity variation was observed on the seasonal trend in 2011. The tendency for magnetic storms to cause increases in TEC is much greater than those of decreases. Daytime maximum TEC usually occurred closer to the noon time during storm periods when compared to those of quiet periods. Maximum percent change in TEC on storm days varied from about 25 to 131 percent.

Beschreibung: Background: This study investigated the effects of salmonella infection and its chemotherapy on lipid metabolism in tissues of rats infected orally with Salmonella typhimurium and treated intraperitoneally with pefloxacin and amoxillin. Methods: Animals were infected with Salmonella enterica serovar Typhimurium strain TA 98. After salmonellosis was confirmed, they were divided into 7 groups of 5 animals each. While one group served as infected control group, three groups were treated with amoxillin (7.14mg/kg body weight, 8 hourly) and the remaining three groups with pefloxacin (5.71mg/kg body weight, 12 hourly) for 5 and 10 days respectively. Uninfected control animals received 0.1ml of vehicle. Rats were sacrificed 24h after 5 and 10days of antibiotic treatment and 5days after discontinuation of antibiotic treatment. Their corresponding controls were also sacrificed at the same time point. Blood and tissue lipids were then evaluated. Results: Salmonella infection resulted in dyslipidemia characterised by increased concentrations of free fatty acids (FFA) in plasma and erythrocyte, as well as enhanced cholesterogenesis, hypertriglyceridemia and phospholipidosis in plasma, low density lipoprotein-very low density lipoprotein (LDL-VLDL), erythrocytes, erythrocyte ghost and the organs. The antibiotics reversed the dyslipidemia but not totally. A significant correlation was observed between fecal bacterial load and plasma cholesterol (r=0.456, p

Beschreibung: Ionospheric irregularities are a regular occurrence at the equatorial latitude during the post sunset hours especially during high solar activity. These irregularities could pose serious challenges to satellite-based navigation and positioning applications by causing fading and degradation of trans-ionospheric signals passing through these irregularities. We have investigated large-scale ionospheric irregularities occurrence at Ilorin, Nigeria (Lat. = 8.48 °N, Long. = 4.67 °W, Dip = 4.1 °S), a station located within the equatorial region in the African sector. The index used in this study is the rate of change of TEC (ROT) derived from 30 seconds RINEX data obtained using a dual frequency GPS receiver (i.e. NovAtel GPStation-2). The study covers a period of four years (2009 to 2012). The results obtained showed that large-scale irregularities occur between March and November and are more pronounced between 1900 LT and 2400 LT. The irregularities were observed to show two peaks; one in March and the other in September. Solar activity trend was also observed. The irregularities level around the peaks seems to increase with solar activity. Although the study covered a period of four years, the period could be regarded as the increasing phase of the solar cycle 24.

Beschreibung: ABSTRACT Epidemiological evidences indicate close association between inorganic arsenic exposure via drinking water and cardiovascular diseases. While the exact mechanism of this arsenic-mediated increase in cardiovascular risk factors remains enigmatic, epidemiological studies indicate a role for paraoxonase 1 (PON1) in cardiovascular diseases. To investigate the association between inorganic arsenic exposure and cardiovascular diseases, rats were exposed to sodium arsenite (trivalent; 50, 100, and 150 ppm As) and sodium arsenate (pentavalent; 100, 150, and 200 ppm As) in their drinking water for 12 weeks. PON1 activity towards paraoxon (PONase) and phenylacetate (AREase) in plasma, lipoproteins, hepatic, and brain microsomal fractions were determined. Inhibition of PONase and AREase in plasma and HDL characterized the effects of the two arsenicals. While the trivalent arsenite inhibited PONase by 33% (plasma) and 46% (HDL), respectively, the pentavalent arsenate inhibited the enzyme by 41 and 34%, respectively. AREase activity was inhibited by 52 and 48% by arsenite, whereas the inhibition amounted to 72 and 67%, respectively by arsenate. The pattern of inhibition in plasma and HDL indicates that arsenite induced a dose-dependent inhibition of PONase whereas arsenate induced a dose-dependent inhibition of AREase. In the VLDL + LDL, arsenate inhibited PONase and AREase while arsenite inhibited PONase. In the hepatic and brain microsomal fractions, only the PONase enzyme was inhibited by the two arsenicals. The inhibition was more pronounced in the hepatic microsomes where a 70% inhibition was observed at the highest dose of pentavalent arsenic. Microsomal cholesterol was increased by the two arsenicals resulting in increased cholesterol/phospholipid ratios. Our findings indicate that decreased PON1 activity observed in arsenic exposure may be an incipient biochemical event in the cardiovascular effects of arsenic. Modulation of PON1 activity by arsenic may also be mediated through changes in membrane fluidity brought about by changes in the concentration of cholesterol in the microsomes. © 2014 Wiley Periodicals, Inc. Environ Toxicol, 2014.

Beschreibung: Background: Bats (Chiroptera) are one of the most diverse groups of mammals which carry out important ecological and agricultural functions that are beneficial to humans. However, they are increasingly recognized as natural vectors for a number of zoonotic pathogens and favourable hosts for zoonotic infections. Large populations of the Straw-Coloured Fruit Bat (Eidolon helvum) colonize the main campus of the Obafemi Awolowo University (OAU), Ile-Ife, Nigeria, but the public health implications of faecal contamination and pollution by these flying mammals is unknown. This study characterized S. aureus obtained from faecal samples of these migratory mammals with a view to determining the clonal types of the isolates, and to investigate the possibility of these flying animals as potential reservoir for zoonotic S. aureus infections. Results: One hundred and seven (107) S. aureus isolates were recovered from 560 faecal samples in eleven roosting sites from January 2008 to February 2010. A large proportion of the isolates were susceptible to antibiotics, and molecular characterization of 70 isolates showed that 65 (92.9%) were assigned in coagulase type VI, while accessory gene typing classified 69 isolates into the following: type I (12; 17.1%), type II (3; 4.3%), type III (1; 1.4%) and type IV (53; 75.7%). On the whole, the isolates were grouped in five (A-E) main genotypes. Of the ten representative isolates selected for multilocus sequence typing (MLST), nine isolates were assigned with new sequence types: ST1725, ST1726, ST1727, ST2463-ST2467 and ST2470. Phylogenetic analysis provided evidence that S. aureus isolates in group C were closely related with ST1822 and associated clones identified in African monkeys, and group D isolates with ST75, ST883 and ST1223. The two groups exhibited remarkable genetic diversity compared to the major S. aureus clade. Conclusions: Antibiotic resistance in faecal S. aureus isolates of E. helvum is low and multiple unique S. aureus lineages co-existed with E. helvum. The Straw-Coloured Fruit Bat in Ile-Ife, Nigeria is colonized predominantly by ST1725, ST1726, ST2463 and ST2470 with distinct genotypic characteristics that are rarely found in humans. This study has demonstrated on the possible existence of a reservoir of indigenous and anciently-divergent S. aureus clones among mammals in Africa.

Beschreibung: Scintillation of radio waves in the L-band frequency is a regular occurrence at the equatorial and auroral regions at night most especially during high solar activity periods. Scintillation is caused by plasma density irregularities and this could cause loss of lock of GNSS signals leading to impairment of the applications that rely on this system. A study on the occurrence of scintillation activity over Ilorin (latitude = 8.48 °N, longitude = 4.67 °W, Geomagnetic Latitude = 1.89 °S), Nigeria was done using S4 index data from NovAtel GPStation-2 receiver (2009 – 2012) and NovAtel GPStation-6 receiver (August 2013 – December 2016) which are both located at this station. The solar maximum period of the solar cycle 24 is located well within the period of this investigation; hence this study provides opportunity to see the occurrence pattern of scintillation during different seasons as well as the pattern from low solar activity to solar maximum. The results obtained showed that scintillation occurs between 21:00 LT and 04:00 LT at the peak of the occurrence in 2014. The time window of occurrence decreases with decrease in solar activity. Similarly, scintillation activity was observed to be more regular during high solar activity and it has two peaks of occurrence in March and October. A solar activity trend was observed in scintillation occurrence; scintillation activity increases with increase in the level of solar activity.