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  • American Institute of Physics (AIP)  (3)
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : American Institute of Physics (AIP)
    Physics of Fluids 4 (1992), S. 30-40 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A constitutive equation for computing particle concentration and velocity fields in concentrated monomodal suspensions is proposed that consists of two parts: a Newtonian constitutive equation in which the viscosity depends on the local particle volume fraction and a diffusion equation that accounts for shear-induced particle migration. Particle flux expressions used to obtain the diffusion equation are derived by simple scaling arguments. Predictions are made for the particle volume fraction and velocity fields for steady Couette and Poiseuille flow, and for transient start-up of steady shear flow in a Couette apparatus. Particle concentrations for a monomodal suspension of polymethyl methacrylate spheres in a Newtonian solvent are measured by nuclear magnetic resonance (NMR) imaging in the Couette geometry for two particle sizes and volume fractions. The predictions agree remarkably well with the measurements for both transient and steady-state experiments as well as for different particle sizes.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 8 (1996), S. 1720-1731 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Results are presented for the effect of solute–fiber hydrodynamic interactions on the hindered diffusion of a spherical macromolecule in random media comprised of cylindrical fibers. Hydrodynamic interactions are calculated by representing the sphere as a collection of point singularities and accounting for the fibers by using a numerical version of slender-body theory. Electrostatic and other nonhydrodynamic interactions are neglected. The calculations show that the hydrodynamic mobility of the solute decreases in an exponential-like fashion as the fiber volume fraction is increased. Also, at a given volume fraction, a medium of thinner fibers hinders solute transport more than a medium of thicker fibers. The results compare well with experimental data, both for protein diffusion in solutions of the polysaccharide Dextran and for protein diffusion in cross-linked agarose gels. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 9 (1997), S. 1562-1572 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Hydraulic permeabilities of polymeric membranes and gels are of interest both for calculating fluid flow rates and hindered diffusion coefficients. We have calculated hydraulic permeabilities for monomodal and bimodal, periodic and random fibrous media. Hydrodynamic interactions between fibers are calculated by applying a numerical version of slender body theory to a collection of fibers in a cubic cell many Brinkman screening lengths in dimension. Results for random media are obtained by averaging over many ensembles of fibers. To account for the surrounding medium, the line distribution of point forces along the fiber axes are replicated throughout space by using the Ewald summation technique. Results for periodic media agree with previous theoretical results up to a fiber volume fraction of 50% for parallel flow and 40% for transverse flow. Hydraulic permeabilities calculated for three-dimensional, disordered media with monomodal and bimodal distributions of fiber radius are compared with existing theories and with experimentally determined hydraulic permeabilities for a range of fiber volume fractions. Specific calculations are performed for agarose and collagen/proteoglycan gel systems, which are well described as bimodal fibrous media and are relevant to bioseparations and physiological systems, respectively. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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