ALBERT

Notes: Thin films of Gd were grown on a glass substrate with a sputtering technique. Measurements of x-ray diffraction, magnetization, and electrical resistance were carried out for different samples that were annealed at various temperatures after the deposition. The deposited films are polycrystalline of hcp structure with preferred orientation, with the (100) plane parallel to the sample surface. The estimated Curie temperature TC of these films changes between 273 and 293 K, depending on the annealing temperature. It is found that this variation of TC is correlated with the relaxation of lattice imperfections.

Notes: Structures and interaction parameters of a three-component amphiphilic microemulsion system consisting of n-decane, water, and an amphiphile AOT (sodium-di-2-ethylhexylsulfosuccinate) have been studied by means of small angle neutron scattering. The scattering curves are fitted with Teubuer and Strey's formula, from which three structural parameters are extracted; the average periodic distance D between the oil and water, the structural correlation length ξ, and the area aH per amphiphile molecule. The same data are further examined in terms of Gompper and Schick's formula, from which three interaction parameters are obtained; the strength of segregation J/T among the oil and water, the amphiphilicity L/T of the amphiphile toward the oil and water, and the critical surfactant volume fraction φcs. These interaction parameters have right order of magnitudes and their implications to structural evolution are discussed. © 1996 American Institute of Physics.

Notes: Ischemic heart disease is one of the most popular and lethal diseases for aged peoples in the world, and is usually diagnosed by transarterial selective coronary arteriography. However, it is rather invasive and somewhat dangerous, so that the selective coronary arteriography is not feasible for prospective screening of coronary occlusive heart disease. Conventional digital subtraction angiography (DSA) is widely known as a relatively noninvasive and useful technique is making a diagnosis of arterial occlusive disease, especially in making the diagnosis of ischemic heart disease. Conventional intravenous subtraction angiography by temporal subtraction, however, has several problems when applying to the moving objects. Digital subtraction method using high-speed switching above and below the K edge could be the ideal approach to this solution. We intend to make a synchrotron radiation digital K-edge subtraction angiography in the above policy, and to apply it to the human coronary ischemic disease on an outpatient basis. The principles and experimental systems have already been described in detail by our coworkers.Our prototype experimental system is situated at the AR (accumulation ring) for TRISTAN project of high energy physics. The available beam size is 70 mm by 120 mm. The electron energy of AR is 6.5 GeV and average beam current is approximately 10 mA. This paper will show the animal experiments of our K-edge subtraction system, and discuss some problems and technical difficulties. Three dogs, weighing approximately 15 kg, were examined to evaluate the ability of our prototype synchrotron radiation DSA unit, that we are now constructing. The dogs were anaesthetized with pentobarbital sodium, intravenously (30 mg/kg). Six french-sized (1.52 mm i.d.) pigtail catheter with multiple side holes were introduced via the right femoral vein into the right atrium by the cutdown technique under conventional x-ray fluoroscopic control. Respiration of the dogs was controlled by a mechanical ventilator. The respirations were held for several seconds when taking the images. Approximately 10 to 15 ml of 76% water soluble iodinated contrast medium (Urografin 76, Schering) was injected by an automatic electronic injector at the rate of approximately 10 ml/s. Three or four times injections were done so as not to exceed the normal renal excretion threshold.Intravenous drip infusion of saline (500 ml/2 h) was used to accelerate the washout of contrast medium via renal system. One hundred micrograms of nitroglycerin were administered, intravenously to dilate the coronary arteries, approximately 3 min prior to contrast injection. Sometimes we used 0.1 mg/kg of beta blockage agent (Propranorol) to decrease the heart rate. Subsequently, the heart rate of the dogs was decreased from approximately 200/s to 100/s. These techniques are commonly used in human examinations. Materials are positioned at left anterior oblique view. The sequential images are now detected above the iodine K edge by an image intensifier (RTP 9240F, Toshiba) and recorded at high signal-to-noise ratio analog video recording system (C1900, Hamamatsu Photonics, S/N 45 dB). Proximal coronary arteries are well visualized, however the distal portions are unsatisfactory, because of the overlapping of the contrast-filled dense heart chambers and pulmonary vessels. Bolus injection of contrast medium is also necessary, unless overlapping is inevitable, so are the same in conventional intravenous DSA. The energy above and below the K edge is now changed by tilting the angle of crystal, mechanically, so it has not sufficient speed to subtract the moving material. Real time A/D converter and frame buffering memories have not been available, until now. Even though there are many limitations in the hardware and many problems to overcome, our preliminary animal experiments allow us to have high expectations.

Notes: To assess the ability of the high-speed K-edge energy subtraction system which was made at beamline 8C of Photon Factory, Tsukuba, we performed an animal experiment. Rabbits were used for the intravenous K-edge subtraction angiography. In this paper, the actual images of the artery obtained by this system, are demonstrated. The high-speed K-edge subtraction system consisted of movable silicon (111) monocrystals, II–ITV, and digital memory system. Image processing was performed by 68000-IP computer. The monochromatic x-ray beam size was 50×60 mm. Photon energy above and below iodine K edge was changed within 16 ms and 32 frames of images were obtained sequentially. The rabbits were anaesthetized by phenobarbital and a 5F catheter was inserted into inferior vena cava via the femoral vein. 1.5 ml/kg of contrast material (Conlaxin H) was injected at the rate of 0.5 ml/kg/s. TV images were obtained 3 s after the starting point of injection. By using this system, the clear K-edge subtracted images were obtained sequentially as a conventional DSA system. The quality of the images were better than that obtained by DSA. The dynamical blood flow was analyzed, and the best arterial image could be selected from the sequential images. The structures of aortic arch, common carotid arteries, right subclavian artery, and internal thoracic artery were obtained at the chest. Both common carotid arteries and vertebral arteries were recorded at the neck. The diameter of about 0.3–0.4 mm artery could be clearly revealed. The high-speed K-edge subtraction system demonstrates the very sharp arterial images clearly and dynamically.

Notes: A fluorescent x-ray source for medical imaging, such as K-edge subtraction angiography and monochromatic x-ray CT, has been developed. Using a 6.5 GeV accumulation ring in Tsukuba, fluorescent x rays, which range from about 30 to 70 keV are generated by irradiating several target materials. Measurements have been made of output intensities and energy spectra for different target angles and extraction angles. The intensities of fluorescent x rays at a 30 mA beam current are on the order of 1–3×106 photons/mm2/s at 30 cm from the local spot where the incident beam is collimated to 1 mm2. A phantom which contains three different contrast media (iodine, barium, gadolinium) was used for the K-edge energy subtraction, and element selective CT images were obtained. © 1995 American Institute of Physics.