Publication Date:
2016-07-07
Description:
Article Some individuals present with multiple synchronous colorectal tumours, but the genetic understanding of this is unclear. Here, the authors use a sequencing strategy to show that the synchronous tumours are genetically independent and the patients harbour rare germline damaging mutations in genes associated with the immune system. Nature Communications doi: 10.1038/ncomms12072 Authors: Matteo Cereda, Gennaro Gambardella, Lorena Benedetti, Fabio Iannelli, Dominic Patel, Gianluca Basso, Rosalinda F. Guerra, Thanos P. Mourikis, Ignazio Puccio, Shruti Sinha, Luigi Laghi, Jo Spencer, Manuel Rodriguez-Justo, Francesca D. Ciccarelli
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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