Publikationsdatum:
2017-12-05
Beschreibung:
Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death, Published online: 05 December 2017; doi:10.1038/s41467-017-02035-9 The differences in virus-host interactions resulting in distinct pathogenicity of seasonal and pandemic influenza A viruses (IAV) are not well understood. Here, the authors show that the hemagglutinin segment from pandemic, but not seasonal, IAV suppresses RIPK3-mediated dendritic cell death, thereby reducing T cell activation.
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
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