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  • 1
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    Dopamine-beta-hydroxylase activity and homovanillic acid in spinal fluid of schizophrenics with brain atrophy (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-05-27
    Description: Schizophrenic patients with high ventricle brain ratios and cortical brain atrophy, as shown by computerized tomography, had decreased spinal fluid concentrations of homovanillic acid and dopamine-beta-hydroxylase activity. These decreased cerebral spinal fluid concentrations in patients with brain atrophy support the proposal of disturbed noradrenaline and dopamine neurotransmission in a subgroup of schizophrenic patients.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van Kammen, D P -- Mann, L S -- Sternberg, D E -- Scheinin, M -- Ninan, P T -- Marder, S R -- van Kammen, W B -- Rieder, R O -- Linnoila, M -- New York, N.Y. -- Science. 1983 May 27;220(4600):974-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6133351" target="_blank"〉PubMed〈/a〉
    Keywords: Adolescent ; Adult ; Aged ; Animals ; Antipsychotic Agents/adverse effects ; Atrophy ; Brain/metabolism/*pathology ; Dopamine/metabolism ; Dopamine beta-Hydroxylase/*cerebrospinal fluid ; Homovanillic Acid/*cerebrospinal fluid ; Humans ; Middle Aged ; Phenylacetates/*cerebrospinal fluid ; Rats ; Schizophrenia/*cerebrospinal fluid ; Tomography, X-Ray Computed
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Underinvestment: the energy technology and R&D policy challenge (1999)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1999-07-31
    Description: This Viewpoint examines data on international trends in energy research and development (R&D) funding, patterns of U.S. energy technology patents and R&D funding, and U.S. R&D intensities across selected sectors. The data present a disturbing picture: (i) Energy technology funding levels have declined significantly during the past two decades throughout the industrial world; (ii) U.S. R&D spending and patents, both overall and in the energy sector, have been highly correlated during the past two decades; and (iii) the R&D intensity of the U.S. energy sector is extremely low. It is argued that recent cutbacks in energy R&D are likely to reduce the capacity of the energy sector to innovate. The trends are particularly troubling given the need for increased international capacity to respond to emerging risks such as global climate change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Margolis -- Kammen -- New York, N.Y. -- Science. 1999 Jul 30;285(5428):690-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Science, Technology and Environmental Policy (STEP) Program, Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, NJ 08544-1013, USA. Energy and Resources Group (ERG), University of California, Berkele.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10426983" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Climate change. Fixing a critical climate accounting error (2009)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2009-11-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Searchinger, Timothy D -- Hamburg, Steven P -- Melillo, Jerry -- Chameides, William -- Havlik, Petr -- Kammen, Daniel M -- Likens, Gene E -- Lubowski, Ruben N -- Obersteiner, Michael -- Oppenheimer, Michael -- Robertson, G Philip -- Schlesinger, William H -- Tilman, G David -- New York, N.Y. -- Science. 2009 Oct 23;326(5952):527-8. doi: 10.1126/science.1178797.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Princeton University, Princeton, NJ 08544, USA. tsearchi@princeton.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19900885" target="_blank"〉PubMed〈/a〉
    Keywords: *Biofuels ; Biomass ; *Carbon ; Carbon Dioxide ; *Climate Change ; Developed Countries ; Developing Countries ; Trees/growth & development
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Inhibition of invasion of epithelial cells by Tiam1-Rac signaling (1997)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1997-12-31
    Description: Tiam1 encodes an exchange factor for the Rho-like guanosine triphosphatase Rac. Both Tiam1 and activated RacV12 promote invasiveness of T lymphoma cells. In epithelial Madin-Darby canine kidney (MDCK) cells, Tiam1 localized to adherens junctions. Ectopic expression of Tiam1 or RacV12 inhibited hepatocyte growth factor-induced scattering by increasing E-cadherin-mediated cell-cell adhesion accompanied by actin polymerization at cell-cell contacts. In Ras-transformed MDCK cells, expression of Tiam1 or RacV12 restored E-cadherin-mediated adhesion, resulting in phenotypic reversion and loss of invasiveness. These data suggest an invasion-suppressor role for Tiam1 and Rac in epithelial cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hordijk, P L -- ten Klooster, J P -- van der Kammen, R A -- Michiels, F -- Oomen, L C -- Collard, J G -- New York, N.Y. -- Science. 1997 Nov 21;278(5342):1464-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Cell Biology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9367959" target="_blank"〉PubMed〈/a〉
    Keywords: Actins/metabolism ; Animals ; Cadherins/metabolism ; *Cell Adhesion ; Cell Line ; Cell Line, Transformed ; Cell Movement ; Cell Transformation, Neoplastic ; Cytoplasm/metabolism ; Epithelial Cells/*cytology/metabolism ; GTP-Binding Proteins/*metabolism ; Hepatocyte Growth Factor/pharmacology ; Intercellular Junctions/*metabolism ; *Neoplasm Invasiveness ; Phenotype ; Proteins/genetics/*metabolism ; Signal Transduction ; rac GTP-Binding Proteins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Assessing the future hydrogen economy (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-10-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kammen, Daniel M -- Lipman, Timothy E -- New York, N.Y. -- Science. 2003 Oct 10;302(5643):226-9; author reply 226-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14551419" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Mortality and greenhouse gas impacts of biomass and petroleum energy futures in Africa (2005)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2005-04-02
    Description: We analyzed the mortality impacts and greenhouse gas (GHG) emissions produced by household energy use in Africa. Under a business-as-usual (BAU) scenario, household indoor air pollution will cause an estimated 9.8 million premature deaths by the year 2030. Gradual and rapid transitions to charcoal would delay 1.0 million and 2.8 million deaths, respectively; similar transitions to petroleum fuels would delay 1.3 million and 3.7 million deaths. Cumulative BAU GHG emissions will be 6.7 billion tons of carbon by 2050, which is 5.6% of Africa's total emissions. Large shifts to the use of fossil fuels would reduce GHG emissions by 1 to 10%. Charcoal-intensive future scenarios using current practices increase emissions by 140 to 190%; the increase can be reduced to 5 to 36% using currently available technologies for sustainable production or potentially reduced even more with investment in technological innovation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bailis, Robert -- Ezzati, Majid -- Kammen, Daniel M -- P01-AG17625/AG/NIA NIH HHS/ -- New York, N.Y. -- Science. 2005 Apr 1;308(5718):98-103.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Energy and Resources Group, University of California, Berkeley, CA 94720-3050, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15802601" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Africa South of the Sahara ; *Air Pollution, Indoor/adverse effects/prevention & control ; *Biomass ; Carbon Dioxide ; Charcoal ; Child ; Costs and Cost Analysis ; Databases, Factual ; *Energy-Generating Resources/economics ; Female ; Forecasting ; Fossil Fuels ; *Greenhouse Effect ; Humans ; Mortality/trends ; *Petroleum ; Public Health/trends ; Pulmonary Disease, Chronic Obstructive/*mortality ; Respiratory Tract Infections/*mortality ; Rural Population ; Urban Population ; Wood
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    [Special Issue Review] City-integrated renewable energy for urban sustainability (2016)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2016-05-20
    Description: To prepare for an urban influx of 2.5 billion people by 2050, it is critical to create cities that are low-carbon, resilient, and livable. Cities not only contribute to global climate change by emitting the majority of anthropogenic greenhouse gases but also are particularly vulnerable to the effects of climate change and extreme weather. We explore options for establishing sustainable energy systems by reducing energy consumption, particularly in the buildings and transportation sectors, and providing robust, decentralized, and renewable energy sources. Through technical advancements in power density, city-integrated renewable energy will be better suited to satisfy the high-energy demands of growing urban areas. Several economic, technical, behavioral, and political challenges need to be overcome for innovation to improve urban sustainability. Authors: Daniel M. Kammen, Deborah A. Sunter
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Modification of phytohormone response by a peptide encoded by ENOD40 of legumes and a nonlegume (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-07-19
    Description: The gene ENOD40 is expressed during early stages of legume nodule development. A homolog was isolated from tobacco, which, as does ENOD40 from legumes, encodes an oligopeptide of about 10 amino acids. In tobacco protoplasts, these peptides change the response to auxin at concentrations as low as 10(-12) to 10(-16)M. The peptides encoded by ENOD40 appear to act as plant growth regulators.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van de Sande, K -- Pawlowski, K -- Czaja, I -- Wieneke, U -- Schell, J -- Schmidt, J -- Walden, R -- Matvienko, M -- Wellink, J -- van Kammen, A -- Franssen, H -- Bisseling, T -- New York, N.Y. -- Science. 1996 Jul 19;273(5273):370-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max-Planck-Institut fur Zuchtungsforschung, Koln, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8662527" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Base Sequence ; Cell Division ; Fabaceae/chemistry/*genetics/growth & development ; *Genes, Plant ; Green Fluorescent Proteins ; Indoleacetic Acids/*pharmacology ; Luminescent Proteins/biosynthesis ; Molecular Sequence Data ; Naphthaleneacetic Acids/pharmacology ; Open Reading Frames ; Plant Growth Regulators ; Plant Proteins/biosynthesis/*genetics/*physiology ; Plant Roots/growth & development/metabolism ; *Plants, Medicinal ; *Plants, Toxic ; Protoplasts/cytology ; RNA, Long Noncoding ; RNA, Untranslated/*physiology ; Recombinant Fusion Proteins ; Tobacco/chemistry/*genetics/growth & development ; Transfection
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    The science and policy of risk (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-06-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kammen, D M -- Wilson, R -- New York, N.Y. -- Science. 1993 Jun 25;260(5116):1863.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8297411" target="_blank"〉PubMed〈/a〉
    Keywords: Electromagnetic Fields/*adverse effects ; Humans ; Risk
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Nod factors and nodulation in plants (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-06-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vijn, I -- das Nevas, L -- van Kammen, A -- Franssen, H -- Bisseling, T -- New York, N.Y. -- Science. 1993 Jun 18;260(5115):1764-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Biology, Agricultural University, Dreijenlaan, Wageningen, The Netherlands.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8511583" target="_blank"〉PubMed〈/a〉
    Keywords: Carbohydrate Sequence ; Cell Division ; Chitin/chemistry/pharmacology/*physiology ; Fabaceae/cytology/genetics/*microbiology ; Genes, Bacterial ; Genes, Plant ; Lipopolysaccharides/chemistry/*metabolism/pharmacology ; Molecular Sequence Data ; *Plants, Medicinal ; Rhizobium/genetics/*physiology ; Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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