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  • 1
    Publication Date: 1998-04-29
    Description: Lateral force microscopy in the wearless regime was used to study the friction behavior of a lipid monolayer on mica. In the monolayer, condensed domains with long-range orientational order of the lipid molecules were present. The domains revealed unexpectedly strong friction anisotropies and non-negligible friction asymmetries. The angular dependency of these effects correlated well with the tilt direction of the alkyl chains of the monolayer, as determined by electron diffraction and Brewster angle microscopy. The molecular tilt causing these frictional effects was less than 15 degrees, demonstrating that even small molecular tilts can make a major contribution to friction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Liley -- Gourdon -- Stamou -- Meseth -- Fischer -- Lautz -- Stahlberg -- Vogel -- Burnham -- Duschl -- New York, N.Y. -- Science. 1998 Apr 10;280(5361):273-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉M. Liley, D. Stamou, U. Meseth, H. Vogel, C. Duschl, Department of Chemistry, Swiss Federal Institute of Technology, CH-1015 Lausanne, Switzerland. D. Gourdon and N. A. Burnham, Department of Physics, Swiss Federal Institute of Technology, CH-1015.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9535654" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2013-05-21
    Description: Invasive species that proliferate after colonizing new habitats have a negative environmental and economic impact. The reason why some species become successful invaders, whereas others, even closely related species, remain noninvasive is often unclear. The harlequin ladybird Harmonia axyridis, introduced for biological pest control, has become an invader that is outcompeting indigenous ladybird species in many countries. Here, we show that Harmonia carries abundant spores of obligate parasitic microsporidia closely related to Nosema thompsoni. These microsporidia, while not harming the carrier Harmonia, are lethal pathogens for the native ladybird Coccinella septempunctata. We propose that intraguild predation, representing a major selective force among competing ladybird species, causes the infection and ultimate death of native ladybirds when they feed on microsporidia-contaminated Harmonia eggs or larvae.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vilcinskas, Andreas -- Stoecker, Kilian -- Schmidtberg, Henrike -- Rohrich, Christian R -- Vogel, Heiko -- New York, N.Y. -- Science. 2013 May 17;340(6134):862-3. doi: 10.1126/science.1234032.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Phytopathology and Applied Zoology, Heinrich-Buff-Ring 26-32, Justus-Liebig-University of Giessen, D-35392 Giessen, Germany. andreas.vilcinskas@agrar.uni-giessen.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23687046" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Beetles/*parasitology/*physiology ; *Food Chain ; Hemocytes/parasitology ; Hemolymph/parasitology ; *Introduced Species ; Nosema/*physiology/ultrastructure
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2014-04-15
    Description: Myelination of the central nervous system requires the generation of functionally mature oligodendrocytes from oligodendrocyte precursor cells (OPCs). Electrically active neurons may influence OPC function and selectively instruct myelination of an active neural circuit. In this work, we use optogenetic stimulation of the premotor cortex in awake, behaving mice to demonstrate that neuronal activity elicits a mitogenic response of neural progenitor cells and OPCs, promotes oligodendrogenesis, and increases myelination within the deep layers of the premotor cortex and subcortical white matter. We further show that this neuronal activity-regulated oligodendrogenesis and myelination is associated with improved motor function of the corresponding limb. Oligodendrogenesis and myelination appear necessary for the observed functional improvement, as epigenetic blockade of oligodendrocyte differentiation and myelin changes prevents the activity-regulated behavioral improvement.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096908/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096908/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibson, Erin M -- Purger, David -- Mount, Christopher W -- Goldstein, Andrea K -- Lin, Grant L -- Wood, Lauren S -- Inema, Ingrid -- Miller, Sarah E -- Bieri, Gregor -- Zuchero, J Bradley -- Barres, Ben A -- Woo, Pamelyn J -- Vogel, Hannes -- Monje, Michelle -- 1S10RR02678001/RR/NCRR NIH HHS/ -- K08 NS070926/NS/NINDS NIH HHS/ -- K08NS070926/NS/NINDS NIH HHS/ -- R01 EY10257/EY/NEI NIH HHS/ -- T32 MH020016/MH/NIMH NIH HHS/ -- UL1 RR025744/RR/NCRR NIH HHS/ -- Howard Hughes Medical Institute/ -- New York, N.Y. -- Science. 2014 May 2;344(6183):1252304. doi: 10.1126/science.1252304. Epub 2014 Apr 10.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departments of Neurology, Neurosurgery, and Pediatrics, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24727982" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigens, Thy-1/genetics ; Behavior, Animal/physiology ; *Cell Differentiation ; Cell Lineage ; Cell Proliferation ; Corpus Callosum/cytology/physiology ; Mice ; Mice, Mutant Strains ; Motor Activity/physiology ; Motor Cortex/cytology/*physiology ; Myelin Sheath/*metabolism ; Nerve Fibers, Myelinated/*metabolism ; Neural Stem Cells/*physiology ; Neurons/*physiology ; Oligodendroglia/*cytology ; Rhodopsin/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1995-01-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vogel, H -- New York, N.Y. -- Science. 1995 Jan 27;267(5197):437.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7824939" target="_blank"〉PubMed〈/a〉
    Keywords: *Aggression ; Animals ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 ; Calcium-Calmodulin-Dependent Protein Kinases/deficiency/genetics ; *Drama ; *Fear ; Humans ; *Literature, Modern ; Male ; Mice ; Mice, Knockout
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2012-06-23
    Description: The reliability of Arctic climate predictions is currently hampered by insufficient knowledge of natural climate variability in the past. A sediment core from Lake El'gygytgyn in northeastern (NE) Russia provides a continuous, high-resolution record from the Arctic, spanning the past 2.8 million years. This core reveals numerous "super interglacials" during the Quaternary; for marine benthic isotope stages (MIS) 11c and 31, maximum summer temperatures and annual precipitation values are ~4 degrees to 5 degrees C and ~300 millimeters higher than those of MIS 1 and 5e. Climate simulations show that these extreme warm conditions are difficult to explain with greenhouse gas and astronomical forcing alone, implying the importance of amplifying feedbacks and far field influences. The timing of Arctic warming relative to West Antarctic Ice Sheet retreats implies strong interhemispheric climate connectivity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Melles, Martin -- Brigham-Grette, Julie -- Minyuk, Pavel S -- Nowaczyk, Norbert R -- Wennrich, Volker -- DeConto, Robert M -- Anderson, Patricia M -- Andreev, Andrei A -- Coletti, Anthony -- Cook, Timothy L -- Haltia-Hovi, Eeva -- Kukkonen, Maaret -- Lozhkin, Anatoli V -- Rosen, Peter -- Tarasov, Pavel -- Vogel, Hendrik -- Wagner, Bernd -- New York, N.Y. -- Science. 2012 Jul 20;337(6092):315-20. doi: 10.1126/science.1222135. Epub 2012 Jun 21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Geology and Mineralogy, University of Cologne, Zuelpicher Strasse 49a, D-50674 Cologne, Germany. mmelles@uni-koeln.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22722254" target="_blank"〉PubMed〈/a〉
    Keywords: Arctic Regions ; *Climate Change ; *Cold Climate ; Geologic Sediments ; Ice Cover ; *Lakes ; Radiometric Dating ; Russia ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2013-09-21
    Description: Comments by de Jong et al., Solter et al., and Sloggett question the ecological relevance of the abundant microsporidia found in the invasive ladybird Harmonia axyridis. We contend that there is abundant evidence that native ladybirds feed on H. axyridis eggs and that interspecific microsporidial transfer is a common phenomenon, supporting the proposed role of these parasites as biological weapons.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vilcinskas, Andreas -- Stoecker, Kilian -- Schmidtberg, Henrike -- Rohrich, Christian R -- Vogel, Heiko -- New York, N.Y. -- Science. 2013 Sep 20;341(6152):1342. doi: 10.1126/science.1242484.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Phytopathology and Applied Zoology, Heinrich-Buff-Ring 26-32, Justus-Liebig-University of Giessen, D-35392 Giessen, Germany. andreas.vilcinskas@agrar.uni-giessen.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24052293" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Beetles/*parasitology/*physiology ; *Food Chain ; *Introduced Species ; Nosema/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2019
    Description: 〈p〉Chromosome evolution presents an enigma in the mega-diverse Lepidoptera. Most species exhibit constrained chromosome evolution with nearly identical haploid chromosome counts and chromosome-level gene collinearity among species more than 140 million years divergent. However, a few species possess radically inflated chromosomal counts due to extensive fission and fusion events. To address this enigma of constraint in the face of an exceptional ability to change, we investigated an unprecedented reorganization of the standard lepidopteran chromosome structure in the green-veined white butterfly (〈i〉Pieris napi〈/i〉). We find that gene content in 〈i〉P. napi〈/i〉 has been extensively rearranged in large collinear blocks, which until now have been masked by a haploid chromosome number close to the lepidopteran average. We observe that ancient chromosome ends have been maintained and collinear blocks are enriched for functionally related genes suggesting both a mechanism and a possible role for selection in determining the boundaries of these genome-wide rearrangements.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
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  • 8
    Publication Date: 2018-08-23
    Description: Curtailed sleep promotes weight gain and loss of lean mass in humans, although the underlying molecular mechanisms are poorly understood. We investigated the genomic and physiological impact of acute sleep loss in peripheral tissues by obtaining adipose tissue and skeletal muscle after one night of sleep loss and after one full night of sleep. We find that acute sleep loss alters genome-wide DNA methylation in adipose tissue, and unbiased transcriptome-, protein-, and metabolite-level analyses also reveal highly tissue-specific changes that are partially reflected by altered metabolite levels in blood. We observe transcriptomic signatures of inflammation in both tissues following acute sleep loss, but changes involving the circadian clock are evident only in skeletal muscle, and we uncover molecular signatures suggestive of muscle breakdown that contrast with an anabolic adipose tissue signature. Our findings provide insight into how disruption of sleep and circadian rhythms may promote weight gain and sarcopenia.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
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