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  • 1
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    Statement on scientific publication and security (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-02-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Atlas, Ronald -- Campbell, Philip -- Cozzarelli, Nicholas R -- Curfman, Greg -- Enquist, Lynn -- Fink, Gerald -- Flanagin, Annette -- Fletcher, Jacqueline -- George, Elizabeth -- Hammes, Gordon -- Heyman, David -- Inglesby, Thomas -- Kaplan, Samuel -- Kennedy, Donald -- Krug, Judith -- Levinson, Rachel -- Marcus, Emilie -- Metzger, Henry -- Morse, Stephen S -- O'Brien, Alison -- Onderdonk, Andrew -- Poste, George -- Renault, Beatrice -- Rich, Robert -- Rosengard, Ariella -- Salzburg, Steven -- Scanlan, Mary -- Shenk, Thomas -- Tabor, Herbert -- Varmus, Harold -- Wimmer, Eckard -- Yamamoto, Keith -- Journal Editors and Authors Group -- New York, N.Y. -- Science. 2003 Feb 21;299(5610):1149.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12595658" target="_blank"〉PubMed〈/a〉
    Keywords: *Access to Information ; *Bioterrorism ; Peer Review, Research ; Periodicals as Topic ; *Publishing ; *Security Measures ; *Terrorism ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Structural features of polysaccharides that induce intra-abdominal abscesses (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-10-15
    Description: The capsular polysaccharide complex from Bacteroides fragilis promotes the formation of intra-abdominal abscesses--a pathologic host response to infecting microorganisms. This complex consists of two distinct polysaccharides, each with repeating units that have positively charged amino groups and negatively charged carboxyl or phosphate groups. Analysis of these polysaccharides as well as other charged carbohydrates before and after chemical modification revealed that these oppositely charged groups are required for the induction of intra-abdominal abscesses in a rat model.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tzianabos, A O -- Onderdonk, A B -- Rosner, B -- Cisneros, R L -- Kasper, D L -- 1F32 AI 084901 AI/AI/NIAID NIH HHS/ -- 2T32AI07061-11AI/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1993 Oct 15;262(5132):416-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Channing Laboratory, Brigham and Women's Hospital, Boston, MA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8211161" target="_blank"〉PubMed〈/a〉
    Keywords: *Abdomen ; Abscess/*microbiology ; Animals ; Bacterial Capsules/*chemistry/toxicity ; Bacteroides Infections/*microbiology ; Bacteroides fragilis/*pathogenicity ; Carbohydrate Sequence ; Male ; Molecular Sequence Data ; Neisseria meningitidis/pathogenicity ; Polysaccharides, Bacterial/chemistry/toxicity ; Rats ; Rats, Wistar ; Salmonella typhi/pathogenicity ; Streptococcus pneumoniae/pathogenicity ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    Host-microbe interactions: virulence mechanisms of bacterial pathogens (1988)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1988-06-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Onderdonk, A B -- New York, N.Y. -- Science. 1988 Jun 3;240(4857):1352-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17815858" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Survival of Escherichia coli host-vector systems in the mammalian intestine (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-18
    Description: Survival in the mouse and human intestine of Escherichia coli host-vector systems used and proposed for recombinant DNA technology was assessed. There was no detectable survival of severely disabled E. coli K12 strain X1776 in mice or in human subjects 24 hours after ingestion. The same strain bearing the plasmid pBR322, however, was recovered from human subjects for 4 days in amounts of six organisms for every million ingested. Nondisabled E. coli K12 strain X1666, with or without pBR322, survived in 10(4)-fold greater numbers and for 2 days longer, with better recovery of the plasmid-containing derivative. Although the plasmid-bearing strains were recovered for longer periods, no intestinal colonization was noted. Despite the presence of pBR322 for a maximum of 6 days in the human intestine, there was no evidence that it was transferred from either bacterial host to endogenous aerobic fecal bacteria.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levy, S B -- Marshall, B -- Rowse-Eagle, D -- Onderdonk, A -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):391-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6992276" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; DNA, Recombinant/metabolism ; Escherichia coli/*physiology ; Humans ; Intestines/*microbiology ; Mice ; Plasmids ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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