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  • 1
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    The neural circuitry of affect-induced distortions of trust (2019)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2019
    Description: 〈p〉Aversive affect is likely a key source of irrational human decision-making, but still, little is known about the neural circuitry underlying emotion-cognition interactions during social behavior. We induced incidental aversive affect via prolonged periods of threat of shock, while 41 healthy participants made investment decisions concerning another person or a lottery. Negative affect reduced trust, suppressed trust-specific activity in the left temporoparietal junction (TPJ), and reduced functional connectivity between the TPJ and emotion-related regions such as the amygdala. The posterior superior temporal sulcus (pSTS) seems to play a key role in mediating the impact of affect on behavior: Functional connectivity of this brain area with left TPJ was associated with trust in the absence of negative affect, but aversive affect disrupted this association between TPJ-pSTS connectivity and behavioral trust. Our findings may be useful for a better understanding of the neural circuitry of affective distortions in healthy and pathological populations.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    New evidence for large earthquakes on the Central Iran plateau: palaeoseismology of the Anar fault (2012)
    Oxford University Press
    Details
    Publication Date: 2012-02-22
    Description: SUMMARY The Central Iran plateau appears aseismic during the last few millenniums based on instrumental and historical seismic records. Nevertheless, it is sliced by several strike-slip faults that are hundreds of kilometres long. These faults display along-strike, horizontal offsets of intermittent gullies that suggest the occurrence of earthquakes in the Holocene. Establishing this is crucial for accurately assessing the regional seismic hazard. The first palaeoseismic study performed on the 200-km long, NS striking Anar fault shows that this right-lateral fault hosted three large ( M w ≈ 7) earthquakes during the Holocene or possibly Uppermost Pleistocene for the older one. These three seismic events are recorded within a sedimentary succession, which is not older than 15 ka, suggesting an average recurrence of at most 5 ka. The six optically stimulated luminescence ages available provide additional constraints and allow estimating that the three earthquakes have occurred within the following time intervals: 4.4 ± 0.8, 6.8 ± 1 and 9.8 ± 2 ka. The preferred age of the more recent event, ranging between 3600 and 5200 yr, suggests that the fault is approaching the end of its seismic cycle and the city of Anar could be under the threat of a destructive earthquake in the near future. In addition, our results confirm a previous minimum slip rate estimate of 0.8 ± 0.1 mm yr −1 for the Anar fault indicating that the westernmost prominent right-lateral faults of the Central Iran plateau are characterized by slip rates close to 1 mm yr −1 . These faults, which have repeatedly produced destructive earthquakes with large magnitudes and long recurrence interval of several thousands of years during the Holocene, show that the Central Iran plateau does not behave totally as a rigid block and that its moderate internal deformation is nonetheless responsible for a significant seismic hazard.
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 3
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    Opsins in Onychophora (Velvet Worms) Suggest a Single Origin and Subsequent Diversification of Visual Pigments in Arthropods (2012)
    Oxford University Press
    Details
    Publication Date: 2012-10-17
    Description: Multiple visual pigments, prerequisites for color vision, are found in arthropods, but the evolutionary origin of their diversity remains obscure. In this study, we explore the opsin genes in five distantly related species of Onychophora, using deep transcriptome sequencing and screening approaches. Surprisingly, our data reveal the presence of only one opsin gene (onychopsin) in each onychophoran species, and our behavioral experiments indicate a maximum sensitivity of onychopsin to blue–green light. In our phylogenetic analyses, the onychopsins represent the sister group to the monophyletic clade of visual r-opsins of arthropods. These results concur with phylogenomic support for the sister-group status of the Onychophora and Arthropoda and provide evidence for monochromatic vision in velvet worms and in the last common ancestor of Onychophora and Arthropoda. We conclude that the diversification of visual pigments and color vision evolved in arthropods, along with the evolution of compound eyes—one of the most sophisticated visual systems known.
    Print ISSN: 0737-4038
    Electronic ISSN: 1537-1719
    Topics: Biology
    Published by Oxford University Press
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  • 4
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    Dating inset terraces and offset fans along the Dehshir Fault (Iran) combining cosmogenic and OSL methods (2011)
    Oxford University Press
    Details
    Publication Date: 2011-04-15
    Description: SUMMARY 10 Be and 36 Cl cosmic ray exposure (CRE) and optically stimulated luminescence (OSL) dating of offset terraces have been performed to constrain the long-term slip rate of the Dehshir fault. Analysis of cosmogenic 10 Be and 36 Cl in 73 surface cobbles and 27 near-surface amalgams collected from inset terraces demonstrates the occurrence of a low denudation rate of 1 m Ma −1 and of a significant and variable inheritance from exposure prior to the aggradation of these alluvial terraces. The significant concentrations of cosmogenic nuclides measured in the cobbles collected within the riverbeds correspond to 72 ± 20 ka of inheritance. The mean CRE age of the surface samples collected on the older terrace T3 is 469 ± 88 ka but the analysis of the distribution of 10 Be concentration in the near-surface samples discard ages older than 412 ka. The mean CRE age of the surface samples collected on terrace T2 is 175 ± 62 ka but the 10 Be depth profile discard ages older than 107 ka. For each terrace, there is a statistical outlier with a younger age of 49.9 ± 3.3 and 235.5 ± 35.4 ka on T2 and T3, respectively. The late sediments aggraded before the abandonment of T2 and inset levels, T1 b and T1a, yielded OSL ages of, respectively, 26.9 ± 1.3, 21.9 ± 1.5 and 10.0 ± 0.6 ka. For a given terrace, the OSL ages, where available, provide ages that are systematically younger than the CRE ages. These discrepancies between the CRE and OSL ages exemplify the variability of the inheritance and indicate the youngest cobble on a terrace, that minimizes the inheritance, is the most appropriate CRE age for approaching that of terrace abandonment. However, the upper bound on the age of abandonment of a terrace that is young with respect to the amount of inheritance is best estimated by the OSL dating of the terrace material. For such terraces, the CRE measurements are complementary of OSL dating and can be used to unravel the complex history of weathering and transport in the catchment of desert alluvial fans. This comprehensive set of dating is combined with morphological offsets ranging from 12 ± 2 to 380 ± 20 m to demonstrate the Dehshir fault slips at a rate in the range 0.9 mm yr −1 –1.5 mm yr −1 . The variable inheritance exemplified here may have significant implications for CRE dating in arid endorheic plateaus such as Tibet and Altiplano.
    Print ISSN: 0956-540X
    Electronic ISSN: 1365-246X
    Topics: Geosciences
    Published by Oxford University Press on behalf of The Deutsche Geophysikalische Gesellschaft (DGG) and the Royal Astronomical Society (RAS).
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  • 5
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    Supernova enrichment and dynamical histories of solar-type stars in clusters (2013)
    Oxford University Press
    Details
    Publication Date: 2013-12-06
    Description: We use N -body simulations of star cluster evolution to explore the hypothesis that short-lived radioactive isotopes found in meteorites, such as 26 Al, were delivered to the Sun's protoplanetary disc from a supernova at the epoch of Solar system formation. We cover a range of star cluster formation parameter space and model both clusters with primordial substructure and those with smooth profiles. We also adopt different initial virial ratios – from cool, collapsing clusters to warm, expanding associations. In each cluster, we place the same stellar population; the clusters each have 2100 stars and contain one massive 25 M star which is expected to explode as a supernova at about 6.6 Myr. We determine the number of solar (G)-type stars that are within 0.1–0.3 pc of the 25 M star at the time of the supernova, which is the distance required to enrich the protoplanetary disc with the 26 Al abundances found in meteorites. We then determine how many of these G-dwarfs are unperturbed ‘singletons’; stars which are never in close binaries, nor suffer sub-100 au encounters, and which also do not suffer strong dynamical perturbations. The evolution of a suite of 20 initially identical clusters is highly stochastic, with the supernova enriching over 10 G-dwarfs in some clusters, and none at all in others. Typically, only ~25 per cent of clusters contain enriched, unperturbed singletons, and usually only one to two per cluster (from a total of 96 G-dwarfs in each cluster). The initial conditions for star formation do not strongly affect the results, although a higher fraction of supervirial (expanding) clusters would contain enriched G-dwarfs if the supernova occurred earlier than 6.6 Myr. If we sum together simulations with identical initial conditions, then ~1 per cent of all G-dwarfs in our simulations are enriched, unperturbed singletons.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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  • 6
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    Oblique stepwise rise and growth of the Tibet plateau (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-11-27
    Description: Two end member models of how the high elevations in Tibet formed are (i) continuous thickening and widespread viscous flow of the crust and mantle of the entire plateau and (ii) time-dependent, localized shear between coherent lithospheric blocks. Recent studies of Cenozoic deformation, magmatism, and seismic structure lend support to the latter. Since India collided with Asia approximately 55 million years ago, the rise of the high Tibetan plateau likely occurred in three main steps, by successive growth and uplift of 300- to 500-kilometer-wide crustal thrust-wedges. The crust thickened, while the mantle, decoupled beneath gently dipping shear zones, did not. Sediment infilling, bathtub-like, of dammed intermontane basins formed flat high plains at each step. The existence of magmatic belts younging northward implies that slabs of Asian mantle subducted one after another under ranges north of the Himalayas. Subduction was oblique and accompanied by extrusion along the left lateral strike-slip faults that slice Tibet's east side. These mechanisms, akin to plate tectonics hidden by thickening crust, with slip-partitioning, account for the dominant growth of the Tibet Plateau toward the east and northeast.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tapponnier, P -- Zhiqin, X -- Roger, F -- Meyer, B -- Arnaud, N -- Wittlinger, G -- Jingsui, Y -- New York, N.Y. -- Science. 2001 Nov 23;294(5547):1671-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institut de Physique du Globe, 4 Place Jussieu, 75252 Paris, France. tappon@ipgp.jussieu.fr〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11721044" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Identification of the 1H-NMR spectra of complex oligosaccharides with artificial neural networks (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-02-01
    Description: Artificial networks can be used to identify hydrogen nuclear magnetic resonance (1H-NMR) spectra of complex oligosaccharides. Feed-forward neural networks with back-propagation of errors can distinguish between spectra of oligosaccharides that differ by only one glycosyl residue in twenty. The artificial neural networks use features of the strongly overlapping region of the spectra (hump region) as well as features of the resolved regions of the spectra (structural reporter groups) to recognize spectra and efficiently recognized 1H-NMR spectra even when the spectra were perturbed by minor variations in their chemical shifts. Identification of spectra by neural network-based pattern recognition techniques required less than 0.1 second. It is anticipated that artificial neural networks can be used to identify the structures of any complex carbohydrate that has been previously characterized and for which a 1H-NMR spectrum is available.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meyer, B -- Hansen, T -- Nute, D -- Albersheim, P -- Darvill, A -- York, W -- Sellers, J -- New York, N.Y. -- Science. 1991 Feb 1;251(4993):542-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Complex Carbohydrate Research Center, Athens, GA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1990429" target="_blank"〉PubMed〈/a〉
    Keywords: *Artificial Intelligence ; Carbohydrate Conformation ; Carbohydrate Sequence ; *Glucans ; Hydrogen ; Magnetic Resonance Spectroscopy/methods ; Molecular Sequence Data ; Oligosaccharides/*chemistry ; Polysaccharides/*chemistry ; *Xylans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Runcaria, a middle devonian seed plant precursor (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-10-30
    Description: The emergence of the seed habit in the Middle Paleozoic was a decisive evolutionary breakthrough. Today, seed plants are the most successful plant lineage, with more than 250,000 living species. We have identified a middle Givetian (385 million years ago) seed precursor from Belgium predating the earliest seeds by about 20 million years. Runcaria is a small, radially symmetrical, integumented megasporangium surrounded by a cupule. The megasporangium bears an unopened distal extension protruding above the multilobed integument. This extension is assumed to be involved in anemophilous pollination. Runcaria sheds new light on the sequence of character acquisition leading to the seed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gerrienne, P -- Meyer-Berthaud, B -- Fairon-Demaret, M -- Streel, M -- Steemans, P -- New York, N.Y. -- Science. 2004 Oct 29;306(5697):856-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departement de Geologie, B18, Universite de Liege, Sart Tilman, Liege 1, Belgique. p.gerrienne@ulg.ac.be〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15514154" target="_blank"〉PubMed〈/a〉
    Keywords: Belgium ; *Biological Evolution ; Fossils ; Plant Physiological Phenomena ; Plant Structures/*anatomy & histology ; Plants/*anatomy & histology/classification ; Pollen ; *Seeds ; Time
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    Health clues from polar regions (2007)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2007-04-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Erren, Thomas C -- Meyer-Rochow, V Benno -- Erren, Michael -- New York, N.Y. -- Science. 2007 Apr 27;316(5824):540.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17463267" target="_blank"〉PubMed〈/a〉
    Keywords: Arctic Regions ; *Biomedical Research ; *Cold Climate ; *Disease ; *Health ; Humans
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    Molecular and cellular reorganization of neural circuits in the human lineage (2017)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2017-11-24
    Description: To better understand the molecular and cellular differences in brain organization between human and nonhuman primates, we performed transcriptome sequencing of 16 regions of adult human, chimpanzee, and macaque brains. Integration with human single-cell transcriptomic data revealed global, regional, and cell-type–specific species expression differences in genes representing distinct functional categories. We validated and further characterized the human specificity of genes enriched in distinct cell types through histological and functional analyses, including rare subpallial-derived interneurons expressing dopamine biosynthesis genes enriched in the human striatum and absent in the nonhuman African ape neocortex. Our integrated analysis of the generated data revealed diverse molecular and cellular features of the phylogenetic reorganization of the human brain across multiple levels, with relevance for brain function and disease.
    Keywords: Neuroscience
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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