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  • National Academy of Sciences  (48)
  • Wiley-Blackwell  (13)
  • American Association for the Advancement of Science (AAAS)  (5)
  • Washington, DC : United States Gov. Print. Off.
  • American Association of Petroleum Geologists (AAPG)
  • 1
    Series available for loan
    Series available for loan
    Geology of the Red Devil quicksilver mine, Alaska (1963)
    Washington, DC : United States Gov. Print. Off.
    Associated volumes
    Details Availability
    Call number: SR 90.0001(1142-G)
    In: U.S. Geological Survey bulletin
    Type of Medium: Series available for loan
    Pages: III, G-16 S. + 7 pl.
    Series Statement: U.S. Geological Survey bulletin 1142-G
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 2
    Series available for loan
    Series available for loan
    Reconnaissance geology of northern Baranof Island, Alaska (1963)
    Washington, DC : United States Gov. Print. Off.
    Associated volumes
    Details Availability
    Call number: SR 90.0001(1141-O)
    In: U.S. Geological Survey bulletin
    Type of Medium: Series available for loan
    Pages: III, O-24 S. + 1 pl.
    Series Statement: U.S. Geological Survey bulletin 1141-O
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 3
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    Arsenic pollution of groundwater in Vietnam exacerbated by deep aquifer exploitation for more than a century [Environmental Sciences] (2011)
    National Academy of Sciences
    Details
    Publication Date: 2011-01-26
    Description: Arsenic contamination of shallow groundwater is among the biggest health threats in the developing world. Targeting uncontaminated deep aquifers is a popular mitigation option although its long-term impact remains unknown. Here we present the alarming results of a large-scale groundwater survey covering the entire Red River Delta and a unique probability model based on three-dimensional Quaternary geology. Our unprecedented dataset reveals that ∼7 million delta inhabitants use groundwater contaminated with toxic elements, including manganese, selenium, and barium. Depth-resolved probabilities and arsenic concentrations indicate drawdown of arsenic-enriched waters from Holocene aquifers to naturally uncontaminated Pleistocene aquifers as a result of 〉 100 years of groundwater abstraction. Vertical arsenic migration induced by large-scale pumping from deep aquifers has been discussed to occur elsewhere, but has never been shown to occur at the scale seen here. The present situation in the Red River Delta is a warning for other As-affected regions where groundwater is extensively pumped from uncontaminated aquifers underlying high arsenic aquifers or zones.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 4
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    Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-12-06
    Description: A polyamide nucleic acid (PNA) was designed by detaching the deoxyribose phosphate backbone of DNA in a computer model and replacing it with an achiral polyamide backbone. On the basis of this model, oligomers consisting of thymine-linked aminoethylglycyl units were prepared. These oligomers recognize their complementary target in double-stranded DNA by strand displacement. The displacement is made possible by the extraordinarily high stability of the PNA-DNA hybrids. The results show that the backbone of DNA can be replaced by a polyamide, with the resulting oligomer retaining base-specific hybridization.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nielsen, P E -- Egholm, M -- Berg, R H -- Buchardt, O -- New York, N.Y. -- Science. 1991 Dec 6;254(5037):1497-500.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biochemistry B, Panum Institute, Copenhagen, Denmark.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1962210" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Molecular Sequence Data ; Molecular Structure ; Nylons/*chemistry ; Oligonucleotides/*chemistry ; Photochemistry ; Thermodynamics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Extensive arsenic contamination in high-pH unconfined aquifers in the Indus Valley (2017)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2017-08-24
    Description: Arsenic-contaminated aquifers are currently estimated to affect ~150 million people around the world. However, the full extent of the problem remains elusive. This is also the case in Pakistan, where previous studies focused on isolated areas. Using a new data set of nearly 1200 groundwater quality samples throughout Pakistan, we have created state-of-the-art hazard and risk maps of arsenic-contaminated groundwater for thresholds of 10 and 50 μg/liter. Logistic regression analysis was used with 1000 iterations, where surface slope, geology, and soil parameters were major predictor variables. The hazard model indicates that much of the Indus Plain is likely to have elevated arsenic concentrations, although the rest of the country is mostly safe. Unlike other arsenic-contaminated areas of Asia, the arsenic release process in the arid Indus Plain appears to be dominated by elevated-pH dissolution, resulting from alkaline topsoil and extensive irrigation of unconfined aquifers, although pockets of reductive dissolution are also present. We estimate that approximately 50 million to 60 million people use groundwater within the area at risk, with hot spots around Lahore and Hyderabad. This number is alarmingly high and demonstrates the urgent need for verification and testing of all drinking water wells in the Indus Plain, followed by appropriate mitigation measures.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor [Medical Sciences] (2017)
    National Academy of Sciences
    Details
    Publication Date: 2017-10-04
    Description: Nuclear receptor corepressor 1 (NCoR1) is considered to be the major corepressor that mediates ligand-independent actions of the thyroid hormone receptor (TR) during development and in hypothyroidism. We tested this by expressing a hypomorphic NCoR1 allele (NCoR1ΔID), which cannot interact with the TR, in Pax8-KO mice, which make no thyroid...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 7
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    Lateral isotopic discontinuity in the lower crust: an example from antarctica (1987)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1987-09-04
    Description: The lower continental crust is one of the least known variables in the crust-mantle evolutionary equation. In order to study the nature and compositional heterogeneity of the lower crust, more than 20 inclusions of lower crustal granulites in volcanic rocks from the McMurdo Sound region of Antarctica were analyzed for strontium and oxygen isotopes. These inclusions were erupted from volcanic centers covering an area of 12,000 square kilometers. Along with results from analyses of major and trace elements, the isotopic data reveal a profound discontinuity in the composition and probably the age of the lower crust that coincides with the boundary between the Transantarctic Mountains and the Ross Embayment. Although this topographic boundary between East and West Antarctica is largely a Cenozoic development, which apparently reflects a simple subvertical faulting relationship due to crustal rifting, the isotopic differences in the lower crust across the boundary suggest that the current faulting and rifting may coincide with an older crustal suture, the age of which is uncertain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kalamarides, R I -- Berg, J H -- Hank, R A -- New York, N.Y. -- Science. 1987 Sep 4;237(4819):1192-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17801643" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
    Electronic Resource
    Electronic Resource
    Startup of an industrial adiabatic tubular reactor (1992)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 38 (1992), S. 1871-1880 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The dynamic behaviour of an adiabatic tubular plant reactor during the startup is demonstrated, together with the impact of a feed-pump failure of one of the reactants. A dynamic model of the reactor system is presented, and the system response is calculated as a function of experimentally-determined, time-dependent, manipulated variables. The values of model parameters are estimated by using the SimuSolv (1991) computer program. The data set collected during the reactor start-up is used for the parameter estimation procedure. An excellent agreement is obtained between the experimental and the calculated system response. Many continuously-operated commercial reactors require a complete conversion of one of the main reactants at the reactor exit. It is shown that for an industrial tubular reactor a much higher initial reactor temperature is required during the startup, compared to the reactor inlet temperature during normal steady-state operation, to ensure a complete reactant conversion. Much more research is necessary to determine whether this is a generally valid rule.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690381204
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  • 9
    Electronic Resource
    Electronic Resource
    Reactor operating procedures for startup of continuously-operated chemical plants (1995)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 41 (1995), S. 148-158 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Rules are presented for the startup of an adiabatic tubular reactor, based on a qualitative analysis of the dynamic behavior of continuously-operated vapor- and liquid-phase processes. The relationships between the process dynamics, operating criteria, and operating constraints are investigated, since a reactor startup cannot be isolated from an entire plant startup. Composition control of the process material is critical to speed up plant startup operations and to minimize the amount of offgrade materials. The initial reactor conditions are normally critical for a successful startup. For process conditioning, a plant should have an operating mode at which the reactor can be included in a recycle loop together with its feed system and downstream process section. Experimental data of an adiabatic tubular reactor startup and thermal runaway demonstrate some operational problems when such an intermediate operating stage is missing. The derived rules are applied to an industrial, highly heat-integrated reactor section, and the resulting startup strategy is summarized in an elementary-step diagram.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690410114
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  • 10
    Electronic Resource
    Electronic Resource
    Startup strategy design and safeguarding of industrial adiabatic tubular reactor systems (1996)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 42 (1996), S. 503-515 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The safeguarding methodology of chemical plants is usually based on controlling the instantaneous values of process state variables within a certain operating window, the process being brought to shutdown when operating constraints are exceeded. This method does not necessarily prevent chemical reactors suffering from a runaway during dynamic operations because (a) excessive amounts of unreacted chemicals can still accumulate in the process, and (b) no means are provided to the operating personnel to identify hazardous process deviations. A model-based startup and safeguarding procedure is developed for an industrial adiabatic tubular reactor to improve process safety during startup. The trajectories of manipulated variables are calculated by minimizing the amount of one of the main reactants in the reactor effuent. It is concluded that proper control of the initial reactor temperature profile is critical for a safe startup while the impact of other manipulated variables is relatively smaller than that of the initial reactor temperature profile.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690420219
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