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  • Springer  (4)
  • Wiley  (2)
  • 1
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Three probands heterozygous for a mutant of apolipoprotein AI (apo AIMarburg, Utermann et al. 1982a) were detected by screening of 2282 unrelated individuals resulting an a frequency estimate of about 1/750 in the German population. All three probands with apo AIMarburg had hypertriglyceridemia (triglyceride above 250 mg/dl) and subnormal HDL-cholesterol (below 30 mg/dl), but no other lipoprotein abnormalities. The kindreds of two probands with AIMarburg were studied. The family data are consistent with an autosomal codominant inheritance of the trait. A total of 16 heterozygous blood relatives with the mutant AIMarburg were detected in these kindreds. Analysis of the plasma lipid and lipoprotein levels in relation to the apo AI phenotype was complicated by the high prevalence of diabetes mellitus and thyroid disease in one kindred and of hyperlipidemia in both kindreds. No consistent relationship between plasma lipid and lipoprotein levels, and the mutant apo AI could be demonstrated. Instead the mutant apo AI and the dyslipoproteinemia seem to co-exist independently in these kindreds. Three sibs with the homozygous apo E-2/2 phenotype were detected in one kindred, and all three sibs had subnormal LDL-cholesterol and beta-VLDL, e.g., the lipoprotein abnormality characterizing primary dysbetalipoproteinemia. Genetic apo E phenotypes and the apo AI mutant segregated independently, indicating that the structural gene loci for apo E and apo AI are not closely linked.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 44 (1957), S. 108-108 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1435-1528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Summary An orifice viscosimeter with automatic measuring device is constructed in which extensional flow is realized in good approximation. With this, together with appropriate rotational viscometers, measurements on concentrated suspensions of rigid spheres in Newtonian liquids are performed. Significant differences are found between viscosities in orifice and shear flows. In extensional flow suspensions of monodisperse glass-spheres with a medium concentration range (0.2 〈Φ 〈 0.52) show lower viscosities than in shear flow, whereas with the highest concentrations (Φ 〉 0.52) extensional viscosities become higher than shear viscosities. These results can be explained by different mechanisms of configurational rearranging of the spheres. In shear flows at very high concentrations transition from viscous to granular flow is observed. Under these conditions monodisperse spheres arrange into hexagonally packed layers which are sliding one upon another. Even a more pronounced effect of flow type is observed when PMMA spheres in oil are used. Now in shear flow shear-thinning occurs, whereas in extensional flow the same as before a constant viscosity is measured of which the value corresponds to the upper Newtonian shear viscosity. This may be explained by the greater effectivity of extensional flow with respect to desagglomeration processes. When in suspensions of glass spheres oil as the suspending medium is substituted by an aqueous solution of glucose higher values of relative viscosities are realized. There are some indications that this is effected by repulsive mutual forces.
    Notes: Zusammenfassung Es wird ein Auslaufviskosimeter mit automatischer Meßwertermittlung konstruiert, in dem in guter Näherung eine Dehnströmung realisiert ist. Hiermit werden in Verbindung mit geeigneten Rotationsviskosimetern vergleichende Messungen an konzentrierten Suspensionen von starren Kugeln in newtonschen Flüssigkeiten durchgeführt, wobei ausgeprägte Unterschiede auftreten. So ergeben sich bei Suspensionen von monodispersen Glaskugeln in Öl in der Dehnströmung für mittlere Konzentrationen (0,2 〈Φ 〈 0,52) deutlich kleinere, für hohe Konzentrationen (Φ 〉 0,52) aber größere Viskositätswerte als in der Scherströmung. Diese Differenzen lassen sich auf unterschiedliche Platzwechselmechanismen zurückführen. Bei Scherströmungen beobachtet man für die höchsten Konzentrationen einen Übergang vom viskosen zum kornartigen Fließen. In monodispersen Systemen ordnen sich dabei die Kugeln zu hexagonal dicht gepackten Schichten, die übereinander gleiten. Noch deutlicher macht sich der Einfluß des Strömungstyps bei Suspensionen mit Plexiglaskugeln in Öl bemerkbar. In der Scherströmung beobachtet man Scherentzähung, wohingegen in der Dehnströmung nach wie vor eine konstante Viskosität gemessen wird, deren Größe genähert dem Grenzwert des oberen newtonschen Bereichs bei der Scherströmung entspricht. Dies ist durch die größere Effektivität der Dehnströmung bezüglich der Desagglomerierung erklärbar. Wird bei den Glaskugel-Suspensionen das Suspensionsmittel Öl durch eine wäßrige Glucose-Lösung ersetzt, so findet man höhere Werte der relativen Viskosität. Es sind gewisse Hinweise dafür vorhanden, daß dies durch abstoßende Wechselwirkungskräfte hervorgerufen wird.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1435-1528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Zusammenfassung Ausrichtungs- und Aggregationseffekte in Kugelsuspensionen mit viskoelastischer Suspensionsflüssigkeit werden aufgezeigt. Bei einem Teil der Bilder handelt es sich um Mikroaufnahmen von ebenen Schichtenströmungen zwischen zwei Glasplatten. Die Kugeln richten sich in Strömungsrichtung aus und kommen einander näher. Bei Berührung verschwindet die Rotationsgeschwindigkeit der Kugeln. Diese Ausrichtung und Anlagerung wird auch in der Dehn- und Rohrströmung beobachtet. Der Orientierungsvorgang ist ein Normalspannungseffekt. Nicht die absolute Höhe der ersten Normalspannungsdifferenz, sondern das Verhältnis der ersten Normalspannungsdifferenz zur Schubspannung ist der wesentliche Parameter. Auf praktische Folgerungen wird kurz hingewiesen.
    Notes: Summary Photographs are presented which demonstrate the alignment and aggregation effects in suspensions of spheres in viscoelastic media. Pictures were taken from plane shear flows between two glass plates. The spheres line up in flow direction and come into contact. If the spheres touch, the rotation ceases. This alignment and association was also observed and photographed in elongational and in pipe flow. The alignment process could be related to normal stresses. A further observation is that the ratio of the first normal stress difference to the shear stress is the determining parameter. Practical aspects are mentioned.
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 2018-02-27
    Description: We present a comprehensive regional bathymetric data compilation for the southwest Indian Ocean (swIOBC) covering the area from 4°S to 40°S and 20°E to 45°E with a spatial resolution of 250 m. For this, we used multibeam and singlebeam data as well as data from global bathymetric data compilations. We generated the swIOBC using an iterative approach of manual data cleaning and gridding, accounting for different data qualities and seamless integration of all different kinds of data. In comparison to existing bathymetric charts of this region, the new swIOBC benefits from nearly four times as many data-constrained grid cells and a higher resolution, and thus reveals formerly unseen seabed features. In the central Mozambique Basin a surprising variety of landscapes were discovered. They document a deep reaching influence of the Mozambique Current eddies. Details of the N-S trending Zambezi Channel could be imaged in the central Mozambique Basin. Maps are crucial not only for orientation but also to set scientific processes and local information in a spatial context. For most parts of the ocean seafloor, maps are derived from satellite data with only kilometer resolution. Acoustic depth measurements from ships provide more detailed seafloor information in tens to hundreds of meters resolution. For the southwest Indian Ocean, all available depth soundings from a variety of sources and institutes are combined in one coherent map. Thus, in areas where depth soundings exist, this map shows the seafloor in so-far unknown detail. This detailed map forms the base for subsequent studies of e.g. the direction of ocean currents, geological and biological processes in the southwest Indian Ocean.
    Electronic ISSN: 1525-2027
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 6
    Publication Date: 2017-06-15
    Description: We present a new coccolithophore productivity reconstruction spanning the last 300 ka in core GeoB12613-1 retrieved from the western tropical Indian Ocean (IO), an area that mainly derives its warm and oligotrophic surface waters from the eastern IO. Application of a calibrated assemblage-based productivity index indicates a reduction in estimated primary productivity (EPP) from 300 ka to the present, with reconstructed EPP values ranging from 91 to 246 g C/m 2 /yr. Coccolithophore assemblages and coccolith fraction Sr/Ca indicate three main phases of productivity change, with major changes at 160 and 46 ka. The productivity and water-column stratification records show both dominant precession and obliquity periodicities, which appear to control the paleoproductivity in the study area over the last two glacial-interglacial cycles. Shallowing of the thermocline due to strengthening of the trade winds in response to insolation maxima resulted to peaks in EPP. Comparison with the eastern IO productivity and stratification coccolithophore data reveals good correspondence with our records, indicating a strong tropical Pacific influence in our study area. Both of these records show high productivity from 300 ka to 160 ka, interpreted to be due to stronger Walker Circulation while the declining productivity from 160 ka to the present day is a consequence of its weakening intensity.
    Print ISSN: 0883-8305
    Electronic ISSN: 1944-9186
    Topics: Geosciences
    Published by Wiley on behalf of American Geophysical Union (AGU).
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