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  • Springer  (108)
  • MDPI Publishing  (14)
  • Molecular Diversity Preservation International (MDPI)  (13)
  • 1
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0878
    Keywords: Hemocytes ; Hemolymph ; Phenoloxidase ; β-1,3-glucan ; Bombyx mori (Insecta)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A monospecific antibody against β-1,3-glucan recognition protein (a 62 kDa protein) of the larval silkworm prophenoloxidase activating system was used to study the localization of the protein. Among tissues from 5th instar larvae, only hemocytes and plasma were shown to contain a 62 kDa polypeptide immunoreactive with the antibody. Ultra-thin sections of the hemocytes were stained by an indirect immunogold staining method. Labelling occurred in the granules and cytoplasm of granulocytes and in the spherules and cytoplasm of spherulocytes. It was most conspicuous in granules of granulocytes and uniformly labelled spherules of spherulocyte, whereas no labelling was evident in prohemocytes, plasmatocytes and oenocytoids. The results are discussed in relation to the mode of recognition of fungi as non-self in insect hemocoel.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0878
    Keywords: Key words Glucocorticoid receptor (GR) ; Immunohistochemistry ; In situ hybridization ; Pituitary ; Rat (Wistar)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract By means of double immunohistochemical techniques and a nonradioisotopic in situ hybridization method, we determined the colocalization pattern of glucocorticoid receptor (GR) and pituitary hormones and the GR messenger RNA (mRNA) expression in the pituitaries of Wistar adult male rats. Immunoreactivity for GR was detected in the nuclei of cells in the anterior and posterior pituitary. Double immunohistochemistry revealed that the colocaliza- tion of GR and anterior pituitary hormones occurred in almost 99% of the growth hormone (GH)-producing cells and adrenocorticotropic hormone (ACTH)-producing cells, and in 67% of the thyroid stimulating hormone (TSH)-producing cells. Almost all of the folliculostellate cells (93%), marginal layer cells (94%) in the anterior pituitary, and pituicytes (96%) in the posterior pituitary immunostained for S100 protein antibody were also immunostained with GR. GR mRNA was abundant in the cytoplasm of anterior and intermediate pituitary cells but scattered sparsely in that of the posterior pituitary. These results suggest that glucocorticoids directly influence certain pituitary cells in order to regulate cell function, including the synthesis and/or secretion of hormones.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1612-1112
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1614-7456
    Keywords: Self-localization ; Wheelchair ; Obstacle avoidance ; Landmark ; Slit-laser
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This paper presents an autonomous wheelchair system with the capability of self-localization and obstacle avoidance. In our system, the ceiling lights are chosen as landmarks to realize the self-localization of the wheelchair, and a laser range-finder is used for obstacle avoidance. First the approaches of landmark recognition and selflocalization for the wheelchair are proposed. Then the principle of obstacle avoidance using a laser range-finder is described. Finally, the total system of the wheelchair is introduced and a navigational experiment is described. Experimental results indicate the effectiveness of our system.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A theoretical model of the longitudinal strength of brittle fibre-reinforced composites with brittle reaction zones was presented for both cases of strongly and weakly bonded fibre/brittle zone interfaces. First, on the basis of the fracture mechanics, a model of the strength of the fibres coated with strongly adhering brittle zones was proposed as a function of the thickness of the brittle zones. Next, the conditions under which debonding occurs at the interfaces were investigated with the aid of the shear lag analysis proposed by Cox. The theoretical model was then examined using composites with strongly and weakly bonded interfaces. The proposed model agreed fairly well with the experimental results. Finally, the permissible thickness of the brittle zone below which no reduction in fibre strength appears was calculated, using the proposed theory, under the condition of strong interfacial bonding, for carbon, boron and silicon carbide fibres which are of practical use. The calculated values of the thickness were smaller than 1 μm.
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  • 7
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract By using the single carbon-steel fibre-copper matrix composites, the important parameters controlling dislocation motions in the fibre, matrix and composite, namely flow stress, internal stress, effective stress, change in flow stress due to change in strain-rate or temperature, stress exponent of strain-rate, effective stress exponent of dislocation velocity, activation volume and activation enthalpy were measured at the stage in which the mechanical interaction between the components was negligible. It was found that all the composite parameters were determined only by the properties of the components and for each parameter, a modified rule of mixtures was derived.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract In order to evaluate the influence of grain size on the strength and flux pinning force of the Nb3Sn compound, the microstructure, tensile behaviour and flux pinning force of the bronze-processed Nb3Sn superconducting composite materials were investigated under various heat treatments. It was found that the strength of the Nb3Sn layer has a strong dependency on the grain size and it can be expressed by the Hall-Petch type relation. The flux pinning force was roughly proportional to the inverse grain size, agreeing with the results of former investigations.
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  • 9
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Multiple fracture phenomenon of coating film on ductile metal fibre was studied by means of a computer simulation technique. The simulation experiments were carried out for various combinations of mechanical factors such as strength of coating film. Young's and shear moduli of fibre and coating film, yield stress of fibre and strain hardening coefficient of fibre and geometrical factors such as diameter of fibre and thickness of coating film. The effects of these factors on the number of fractures of the coating film and length of segmented film as a function of applied tensile stress and elongation to failure of coated fibre were clarified.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The crystal growth of Nb3Sn by the bronze method has been investigated by using diffusion couples consisting of niobium and bronze with the addition of third elements. When the specimens were annealed at temperatures between 973 and 1073 K, the time-dependence of layer thickness was represented approximately by the function ofd=kt m . The time exponent changed from 1/3 to unity depending on the annealing condition as well as on the nature of the third element. By the addition of titanium, hafnium, zirconium, indium and galium to the bronze, the growth rate of the compound layer increases. Faster layer growth corresponds to a larger time exponent. The following three processes are suggested to be important for controlling layer growth: diffusivity of tin atoms through grain boundaries in the compound layer, diffusivity of tin atoms through the matrix of the compound, and the rate of the chemical reaction to form the compound. Essentially these combined processes control the overall rate of layer growth. The grain size is found to be the most effective structural parameter to affect directly the maximum global pinning force. The critical current at a magnetic field of 5T can be scaled by both the layer thickness and the inverse grain size.
    Type of Medium: Electronic Resource
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