ISSN:
1420-9071
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary It is possible to isolate from the brain a fraction closely allied to ketosteroids which, when injected subcutaneously into adrenalectomized rats in suitable quantity, causes a diminution of lymphocytes, while in adrenalectomized mice it increases the hepatic glycogen, though not to any high degree. The injection of this substance in the rat induces a diminution of the tonus of abdominal and hind leg muscles, catatonia and drowsiness. These symptoms disappear temporarily after repeated mechanical stimulations, and reappear when the subject is left in peace and may continue for some hours; subsequently the animals do not manifest any apparent irreversible symptoms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02170721
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