ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Measurements of 17O-NMR-chemical shifts (relative to H2O) have been carried out in a variety of 125 compounds of which 115 are organic.1The resonance of singly bonded oxygen is shifted to low field by all substituents except CH3. The effects of atoms directly bonded to oxygen increases in the order H, C, S, Cl 〈 N 〈 O. Double bonds —O—C=X (X = C, 0) give rise to considerable shifts, whereas groups bonded to C affect the resonance only slightly.2In carbonyl groups the resonance of doubly bonded oxygen is shifted to high field (relative to acetaldehyde) by all substituents. The effect of heteroatoms bonded to C decreases in the order N 〉 O 〉 F 〉 Cl 〉 Br. Conjugation does not affect the shifts. The chemical shifts of the carbonyl group are sensitive to solvents.3An isotope effect on the chemical shift has been detected in water (H317O/D217O).
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19610440331
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