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  • GEOPHYSICS  (18)
  • Polymer and Materials Science  (11)
  • Cell & Developmental Biology
  • 1975-1979  (28)
  • 1965-1969  (5)
  • 1
    Electronic Resource
    Electronic Resource
    Use of auger and x-ray photoelectron spectroscopy to study the locus of failure of structural adhesive joints (1977)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 21 (1977), S. 2375-2392 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The techniques of Auger electron spectroscopy (AES) and x-ray photoelectron spectroscopy (XPS) have been used to study the locus of failure of epoxy resin joints. The effects of a long water immersion and the application of a silane-based primer have also been studied. Results indicated that for dry joints fracture occurred near an epoxy resin/metal interface while with water-soaked unprimed joints, fracture occurred interfacially between the adhesive and iron oxide. The application of the primer to the metal surface prior to bonding prevented the formation of a water-formed oxide although fracture was then found to occur through the primer.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1977.070210907
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  • 2
    Electronic Resource
    Electronic Resource
    Controlled drug release by polymer dissolution. I. Partial esters of maleic anhydride copolymers - properties and theory (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 22 (1978), S. 1991-2009 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The kinetics of drug release from a series of partial esters of vinyl acetate-maleic anhydride has been investigated. These polymers in their un-ionized forms are hydrophobic and water insoluble, but in their ionized forms they are water soluble. Polymer dissolution is pH sensitive, and different half-esters have a characteristic pH range above which they are soluble and below which they are insoluble. When films are placed in buffered media, they erode at a constant rate that depends on the pH of dissolution of the polymer and on the pH of the buffered medium. Dissolution of the polymer is limited to the polymer-buffer medium interface, and drugs dissolved or uniformly dispersed in the polymer are released by zero-order kinetics. A detailed model has been developed that successfully correlates dissolution behavior and various experimental parameters.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1978.070220720
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  • 3
    Electronic Resource
    Electronic Resource
    Water and solute transport across cellulose acetate membranes in the treatment of soybean whey by reverse osmosis (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 24 (1979), S. 1775-1775 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1979.070240718
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  • 4
    Electronic Resource
    Electronic Resource
    Computer optimization of reverse osmosis processing of soy whey with cellulose acetate modules (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 24 (1979), S. 749-762 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In processing full-fat soy flour to an acid-precipitated lipid protein concentrate a byproduct whey fraction results which, because of its high biological oxygen demand, represents a serious disposal problem. Processing of food waste streams by reverse osmosis has received considerable attention because of its low theoretical energy requirement since no phase change is involved. In a previous study at this Center a mathematical model was developed for the diffusive transport of soy lipid protein concentrate whey across cellulose acetate membranes. In this study, pumping energy and power costs combined with membrane life and replacement costs were incorporated into the original model to provide a basis for optimization from an energy cost standpoint. Computer-simulated runs were compared with experimental pilot-plant runs, and the agreement between predicted and actual results was quite good. Water flux rates were in the range of 3 to 7 gal/ft2/day. Computer runs were used to optimize the processing of 100,000 gal/day of soy whey at 8000 ppm biological oxygen demand (BOD). Costs were at a minimum with a six-stage tapered flow primary reverse osmosis treatment over a porous cellulose acetate membrane, followed by a six-stage tapered flow reverse osmosis over a tighter membrane. BOD reduction was 94% at a cost of $5.45/1000 gal.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1979.070240312
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  • 5
    Electronic Resource
    Electronic Resource
    Methods of fractionating polymers by ultrafiltration (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 13 (1969), S. 369-376 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Polyvinylpyrrolidone and dextran polysaccharides have been fractionated by ultrafiltration by using newly developed membranes with sharp molecular weight cutoffs. Three different experimental techniques were employed: (a) batch ultrafiltration by using progressively more retentive membranes; (b) continuous ultrafiltration by using several similar membranes in series; (c) variable pressure ultrafiltration by using a single membrane and varying the applied pressure. Ultrafiltration is shown to be a technique of preparative fraction having the advantages of simplicity, speed, and economy.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1969.070130210
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  • 6
    Electronic Resource
    Electronic Resource
    Water and solute transport across cellulose acetate membranes in the treatment of soybean whey by reverse osmosis (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 24 (1979), S. 135-145 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In processing full-fat soy flour to produce an acid-precipitated lipid protein concentrate, there results a by-product whey fraction which, because of its high biological oxygen demand, represents a serious disposal problem. Processing of food waste streams by reverse osmosis has received considerable attention because of its low theoretical energy requirement, since no phase change is involved. A series of statistically designed and analyzed experiments were conducted on a pilot-plant reverse osmosis unit to study the effect of the operating parameters on solute and solvent transport in cellulose acetate membranes. Sucrose and sodium chloride solutions were tested in addition to soybean whey to relate the mixed solute system in whey to that of single-solute organic and inorganic feed solutions. Water flux was shown to have an Arrhenius dependency on temperature, and some membrane compaction was observed with the more porous membrane. Concentration polarization for sucrose and sodium chloride solutions increased linearly with water flux. Solute flux for soybean whey solutions decreased with molarity and was independent of pressure, whereas solute rejection increased with temperature and pressure and was independent of molarity. Good agreement was obtained using the derived parameters A, B, and τ for soy whey in the diffusion transport model when compared to the observed experimental values.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1979.070240112
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  • 7
    Electronic Resource
    Electronic Resource
    Growth enhancement of myogenic tumor cells by conditioned medium from embryo fibroblastsThis research was supported by grants from the Cancer Council of Western Australia and the National Health and Medical Research Council. (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 86 (1975), S. 321-326 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Growth medium was conditioned by incubation on mouse embryo cells in vitro. Supplementation of agar suspension cultures with conditioned medium from primary cells, but not from established lines, readily enhanced colony development by mouse tumor cells. Only cells with the properties of myoblasts responded to conditioned medium. Other fibroblastoid cells and virus-transformed cell lines were not affected. Myogenic cells in agar cultures grew in the presence of conditioned medium but did not differentiate. Soluble collagen at 400 m̈g/ml possessed little colony-stimulating activity by comparison with fresh conditioned medium.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040860403
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  • 8
    Electronic Resource
    Electronic Resource
    Control of granulopoiesis in man. III. Inhibition of colony formation by dense leukocytesSupported by Grant 263, The Ontario Cancer Treatment and Research Foundation. (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 86 (1975), S. 337-342 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Cellular feeder layers, prepared from normal blood leukocytes, usually stimulate human marrow to form colonies. A significant increase in the stimulating activity of unseparated leukocyte feeder layers is brought about following the removal of dense leukocytes in a manner which avoids enrichment of any remaining cell type. Restoration of dense leukocytes to a dense leukocyte depleted leukocyte feeder layer results in the reduction of stimulating activity to that of an unseparated leukocyte feeder; however, addition of dense leukocytes to unseparated leukocyte feeder layers has no effect on the stimulatory activity, over the range of concentrations used in this study.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040860405
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  • 9
    Electronic Resource
    Electronic Resource
    Glucocorticoids enhance the mitogenic action of insulin in serum-free cultures of chick embryo cells (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 98 (1979), S. 561-570 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Addition of insulin to nonproliferating serum-free cultures of secondary chicken embryo (CE) cells caused a 30% to 50% increase in cell number. Addition of any one of several glucocorticoids (dexamethasone, cortisol, or corticosterone) to the cultures two days before insulin addition increased the mitogenic effect of insulin by about twofold at each insulin concentration tested. This glucocorticoid stimulation of cell proliferation was “permissive” because in the absence of insulin glucocorticoids caused little increase in cell number (usually less than 15%). Glucocorticoids were maximally active at low concentrations (e.g., 10-10 M dexamethasone). Steroids without glucocorticoid activity were inactive over a wide range of concentrations. Glucocorticoids increased the mitogenic response to insulin largely by increasing the percentage of cells that insulin stimulated to synthesize DNA.The maximum mitogenic effect of insulin upon CE cells rapidly decreased after the cells were serially subcultured. After only nine population doublings (4 passages) in culture, the response to insulin was diminished by about 70%. The mitogenic effect of insulin plus dexamethasone declined similarly during serial subculture, and was always about twofold greater than the effect of insulin alone. The cells maintained their mitogenic responsiveness to serum as these responses decreased.In contrast to the growth promoting influence of glucocorticoids in the presence of insulin, glucocorticoids inhibited the mitogenic response of CE cells to serum. This result may resolve our above findings with reports that glucocorticoids inhibit the proliferation of CE cells.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040980314
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  • 10
    Electronic Resource
    Electronic Resource
    Characteristics of concanavalin A-resistant Chinese hamster ovary cells and certain revertants (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 100 (1979), S. 39-54 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Clones of Chinese hamster ovary (CHO) cells were isolated by single-step selection for resistance to killing by Concanavalin A (ConA) and certain cellular and membrane properties were examined. The ConA-resistant isolates were only about 2-fold more resistant than wild type cells to the selecting lectin, but exhibited pleiotropic temperature-sensitivity for growth, markedly altered morphology and adherence, and significant differences in susceptibility to other agents such as colchicine. Two revertants to full temperature-resistance were isolated from different ConA-resistant mutants. One revertant clone had reacquired wild type sensitivity to ConA while the other revertant remained ConA-resistant. The two series of wild type, ConA-resistant, and temperature revertant clones were analyzed for altered mobility of cell surface glycoproteins using lactoperoxidase/125I and galactose oxidase/[3H]borohydride labelling procedures. The ConA-resistant clones showed increased mobility on polyacrylamide gels of three classes of labelled proteins, in the molecular weight ranges 225,000, 200,000, and 130,000 daltons. These changes persisted in the temperature-revertant that remained ConA-resistant, while two of the altered protein classes were restored to wild type mobility in the revertant that regained ConA-sensitivity. Cell hybridization experiments indicated that the temperature-sensitive phenotypes of different ConA-resistant isolates are recessive and noncomplementing, implying that the same gene is affected in each case. The reversions to temperature resistance appear to be recessive suppressor mutations in different genes.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041000105
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