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  • 1
    Publication Date: 1979-04-20
    Description: Isolated rat islets remain morphologically and functionally intact during a 7-day period of in vitro culture at 24 degrees C. In vitro culture of islets at 24 degrees C for 7 days prior to transplantation, in conjunction with a single injection of antiserum to lymphocytes into the diabetic recipient, results in islet allograft survival of 100 days when the islets are transplanted across a major histocompatibility barrier.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lacy, P E -- Davie, J M -- Finke, E H -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):312-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/107588" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Antilymphocyte Serum ; Culture Techniques ; Diabetes Mellitus, Experimental/therapy ; Graft Survival ; Histocompatibility Antigens ; *Islets of Langerhans Transplantation ; Male ; Rats ; Time Factors ; Transplantation, Homologous
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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