Publication Date:
1979-04-20
Description:
Isolated rat islets remain morphologically and functionally intact during a 7-day period of in vitro culture at 24 degrees C. In vitro culture of islets at 24 degrees C for 7 days prior to transplantation, in conjunction with a single injection of antiserum to lymphocytes into the diabetic recipient, results in islet allograft survival of 100 days when the islets are transplanted across a major histocompatibility barrier.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lacy, P E -- Davie, J M -- Finke, E H -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):312-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/107588" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
*Antilymphocyte Serum
;
Culture Techniques
;
Diabetes Mellitus, Experimental/therapy
;
Graft Survival
;
Histocompatibility Antigens
;
*Islets of Langerhans Transplantation
;
Male
;
Rats
;
Time Factors
;
Transplantation, Homologous
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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