ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The electron-acceptor properties of arylsulfonyl and carbobenzoxy groups decrease the probability of primary electrophilic attack at the nitrogen atom. They also determine primary attack at the 3-C atom of the indole ring. Michael addition products, 3,4-dihydro-α-carbolines, and α-carbolines themselves are obtained, depending on the reaction conditions. The reaction with α,β-unsaturated ketones proceeds under milder conditions in the case of 2-benzyloxycarbonylaminoindole.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00471642
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