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  • 1
    Publication Date: 2006-01-12
    Description: Results are presented of the Biocore experiment which attempted to assess the degree to which exposure to cosmic ray particle radiation might present a risk to astronauts. Pocket mice, with plastic dosimeters implanted beneath the scalp were flown in a sealed canister. The objective was to determine whether microscopically visible lesions attributable to particle radiation, could be found in brain, eye, and other tissues in these animals. The need for further study is demonstrated.
    Keywords: AEROSPACE MEDICINE
    Type: Biomedical Results of Apollo; p 381-403
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  • 2
    Publication Date: 2006-01-12
    Description: Quarantine testing was conducted to ensure the safety of all life on earth. The plants and animals which were exposed to lunar material were carefully observed for prolonged periods to determine if any mutation or changes in growing characteristics and behavior occurred. The quarantine testing was terminated after the Apollo 14 flight when it became apparent that previously returned lunar material contained no potentially harmful agents. Further biological experimentation with the lunar material was conducted to determine its chemical, physical, and nutritional qualities.
    Keywords: AEROSPACE MEDICINE
    Type: Biomedical Results of Apollo; p 425-434
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  • 3
    Publication Date: 2006-01-16
    Description: The validity of biomedical research using animal subjects is highly dependent on the use of 'normal' and healthy animals. The current costs of research programs dictate that a minimum number of animals and test replicates be used to obtain the desired data. The use of healthy and standardized animals increases the probability of obtaining valid data while also permitting greater economy by reducing the between-individual variation, thus allowing the use of fewer animals. Areas of concern when planning animal payloads include constraints of the flight on candidate species selection, screening for physiological and psychological normalcy, procedures for routine care and quarantine of new animals and those returning from space, ground-based studies to determine experimental protocol, selection of instrumentation, stress during transportation for flight operations, housing and care facilities at launch and recovery sites, and the overall veterinary program.
    Keywords: LIFE SCIENCES (GENERAL)
    Type: The Use of Nonhuman Primates in Space; p 197-201
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  • 4
    Publication Date: 2011-08-16
    Description: Looping behavior of minnows aboard Skylab 3 is analyzed. Extensive looping patterns were observed at first look on the third day of weightlessness; thereafter, the frequency of the looping episodes diminished until complete adaptation on the twenty-first day, at which time the fish oriented themselves with their backs to the light. The swimming anomaly could be due to (1) absence of continuous bending of sense hairs to a certain extent by gravity, causing the fish to tilt forward in an attempt to increase leverage on the hairs - in the absence of all gravity, tilting is continued into looping (this hypothesis is supported by parabolic flight experiments with partial gravity, in which only tilting was seen); or (2) an attempt by the fish to create a gravitoinertial stimulus by 'centrifuging' its otoliths by looping.
    Keywords: LIFE SCIENCES (GENERAL)
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  • 5
    Publication Date: 2011-08-16
    Description: In the five pocket mice flown on Apollo XVII, no evidence was found that the inner ear had been damaged, though poor fixation precluded detailed study. On the other hand, the middle ear cavity was involved in all the mice, hemorrhage having occurred in response to excursions in pressure within the canister that housed the mice during their flight. The same occurred in flight control mice which had been subjected to pressure excursions of much the same magnitude. A greater degree of exudation into air cells and greater leukotaxis were noted in the flight animals than in the control animals. There was no increase in leukocyte population along the paths of the 23 cosmic-ray particles registered in the subscalp dosimeters that traversed the middle ear cavities of the flight mice. The increased exudation and the greater response by leukocytes in the flight mice may have been causally related to the lesions found in their olfactory mucosa but there were no data in support of this possibility.
    Keywords: LIFE SCIENCES (GENERAL)
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  • 6
    Publication Date: 2011-08-16
    Description: Studies carried out on the pocket mouse colony on Apollo XVII are reported. They revealed no serological evidence of viral disease, no pathogenic enterobacteria or respiratory Mycoplasma on culture, a 25% incidence of sarcosporidiosis, and a 2% incidence of chronic meningitis or meningoencephalitis. It is concluded that the pocket mouse is a highly adaptive animal and very well-suited to space flight.
    Keywords: LIFE SCIENCES (GENERAL)
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  • 7
    Publication Date: 2011-08-17
    Description: The channeling probe described in the present paper was designed to overcome surgical problems of the type that were encountered when a multichannel radio transmitter had to be implanted in a cow. The probe was made of a flexible but sufficiently stiff 9.5-mm-diam nylon rod, consisting of 46-cm sections for convenience in sterilization and surgical handling. Stainless steel sleaves reinforced the threaded connecting joints. At one end, arrowhead-shaped channeling heads could be attached to produce wide channels for large sensors. The other end was tapered for narrow channels. Postoperative problems were not encountered in the use of this probe in cows, sheep, and dogs.
    Keywords: MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT
    Type: Laboratory Animal Science; 27; Dec. 197
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  • 8
    Publication Date: 2019-06-27
    Description: A total of four Martian samples, one surface and one subsurface sample at each of the two Viking landing sites, Chryse Planitia and Utopia Planitia, have been analyzed for organic compounds by a gas chromatograph-mass spectrometer. In none of these experiments could organic material of Martian origin be detected at detection limits generally of the order of parts per billion and for a few substances closer to parts per million. The evolution of water and carbon dioxide, but not of other inorganic gases, was observed upon heating the sample to temperatures of up to 500 C. The absence of organic compounds seems to preclude their production on the planet at rates that exceed the rate of their destruction. It also makes it unlikely that living systems that behave in a manner similar to terrestrial biota exist, at least at the two Viking landing sites.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Journal of Geophysical Research; 82; Sept. 30
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  • 9
    Publication Date: 2019-06-27
    Description: Equilibrium thermodynamic properties for pure ammonia were generated for a range of temperature from 500 to 50,000 K and pressure from 0.01 to 40 MN/sq m and are presented in tabulated and graphical form. Properties include pressure, temperature, density, enthalpy, speed of sound, entropy, molecular-weight ratio, specific heat at constant pressure, specific heat at constant volume, isentropic exponent, and species mole fractions. These properties were calculated by the method which is based on minimization of the Gibbs free energy. The data presented herein are for an 18-species ammonia model. Heats of formation and spectroscopic constants used as input data are presented. Comparison of several thermodynamic properties calculated with the present program and a second computer code is performed for a range of pressure and for temperatures up to 30,000 K.
    Keywords: THERMODYNAMICS AND STATISTICAL PHYSICS
    Type: NASA-SP-3099
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  • 10
    Publication Date: 2019-06-27
    Description: A self-contained breathing apparatus with automatic redundant fluid pressure controls and a facemask mounted low pressure whistle alarm is described. The first stage of the system includes pair of pressure regulators connected in parallel with different outlet pressures, both of which reduce the pressure of the stored supply gas to pressures compatible with the second stage breathing demand regulator. A primary regulator in the first stage delivers a low output pressure to the demand regulator. In the event of a failure closed condition of the primary regulator an automatic transfer valve switches on the backup regulator. A warning that the supply pressure has been depleted is also provided by a supply pressure actuated transfer valve which transfers the output of the first stage pressure regulators from the primary to the backup regulator. The alarm is activated in either the failure closed condition or if the supply pressure is reduced to a dangerously low level.
    Keywords: MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT
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