Publication Date:
1978-05-05
Description:
The nucleotide sequence of SV40 DNA was determined, and the sequence was correlated with known genes of the virus and with the structure of viral messenger RNA's. There is a limited overlap of the coding regions for structural proteins and a complex pattern of leader sequences at the 5' end of late messenger RNA. The sequence of the early region is consistent with recent proposals that the large early polypeptide of SV40 is encoded in noncontinguous segments of DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Reddy, V B -- Thimmappaya, B -- Dhar, R -- Subramanian, K N -- Zain, B S -- Pan, J -- Ghosh, P K -- Celma, M L -- Weissman, S M -- New York, N.Y. -- Science. 1978 May 5;200(4341):494-502.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/205947" target="_blank"〉PubMed〈/a〉
Keywords:
Base Sequence
;
Chromosome Mapping
;
Codon
;
DNA Replication
;
DNA, Circular
;
DNA, Viral
;
Genes
;
*Genes, Viral
;
Simian virus 40/*genetics
;
Transcription, Genetic
;
Viral Proteins/genetics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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