ISSN:
1573-4919
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
Notes:
Summary The effect of cortisol on rabbit erythrocyte and reticulocyte acid phosphatase was studied. Isoenzymic form I (slow) was activated by cortisol, and protected towards inhibition by phosphate and fluoride. Incubation of isoenzyme III (fast) preparation with cortisol resulted in decrease of the enzyme activity and its affinity for substrate. The inhibition of form III by phosphate and fluoride was accelerated in the presence of cortisol. Form II, if present, was unaffected by cortisol. Reticulocyte isoenzymes I and III were less affected by cortisol than the erythrocyte enzymes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00231314
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