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  • 1980-1984  (3)
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  • 1
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    Effects of water immersion on plasma catecholamines in normal humans (1983)
    In:  Other Sources
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    Publication Date: 2019-06-28
    Description: An investigation was conducted in order to determine whether water immersion to the neck (NI) alters plasma catecholamines in normal humans. Eight normal subjects were studied during a seated control study (C) and during 4 hr of NI, and the levels of norepinephrine (NE) and epinephrine (E) as determined by radioenzymatic assay were measured hourly. Results show that despite the induction of a marked natriuresis and diuresis indicating significant central hypervolemia, NI failed to alter plasma NE or E levels compared with those of either C or the corresponding prestudy 1.5 hr. In addition, the diuresis and natriuresis was found to vary independently of NE. These results indicate that the response of the sympathetic nervous system to acute volume alteration may differ from the reported response to chronic volume expansion.
    Keywords: AEROSPACE MEDICINE
    Type: Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology (ISSN 0161-7567); 54; Jan. 198
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    Characterization of renal response to prolonged immersion in normal man (1980)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: ?jDuring the initial phase of space flight, there is a translocation of fluid from the lower parts of the body to the central vascular compartment with a resultant natriuresis, diuresis, and weight loss. Because water immersion is regarded as an appropriate model for studying the redistribution of fluid that occurs in weightlessness, an immersion study of relatively prolonged duration was carried out in order to characterize the temporal profile of the renal adaptation to central hypervolemia. Twelve normal male subjects underwent an immersion study of 8-h duration in the sodium-replete state. Immersion resulted in marked natriuresis and diuresis which were sustained throughout the immersion period. The failure of that natriuresis and diuresis of immersion to abate or cease despite marked extracellular fluid volume contraction as evidenced by a mean weight loss of -2.2 + or - 0.3 kg suggests that central blood volume was not restored to normal and that some degree of central hypervolemia probably persisted.
    Keywords: AEROSPACE MEDICINE
    Type: Journal of Applied Physiology: Respiratory; vol. 49
    Format: text
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    NASA TECHNICAL REPORTS
  • 3
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    Effects of vasopressin administration on diuresis of water immersion in normal humans (1981)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: The influence of vasopressin suppression on the diuresis encountered during water immersion is investigated in studies on normal humans immersed to the neck. Six hydrated male subjects were studied on two occasions while undergoing 6 h of immersion without or during the administration of aqueous vasopressin for the initial 4 h. Neck immersion is found to result in a significant increase in urinary flow rate beginning in the first hour and persisting throughout the immersion. The administration of vasopressin markedly attenuated the diuretic response throughout the period of infusion, while cessation of vasopressin administration during the final 2 h of immersion resulted in a marked offset of the antidiuresis. Results thus support the view that the suppression of antidiuretic hormone contributes to the immersion diuresis of hydrated subjects.
    Keywords: AEROSPACE MEDICINE
    Type: Journal of Applied Physiology: Respiratory; vol. 51
    Format: text
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    NASA TECHNICAL REPORTS
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