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  • Articles  (93)
  • Springer  (93)
  • 2000-2004  (24)
  • 1980-1984  (52)
  • 1920-1924  (1)
  • 1905-1909  (16)
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  • Articles  (93)
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  • 1
    Electronic Resource
    Electronic Resource
    Preparation of a human lung purified plasma membrane fraction: Confirmation by enzyme markers, electron microscopy, and histamine H1 receptor binding (1984)
    Springer
    The journal of membrane biology 79 (1984), S. 33-39 
    Details
    ISSN: 1432-1424
    Keywords: plasma membrane ; lung ; histamine receptors ; 5′ nucleotidase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary A simple and rapid method of isolating plasma membranes from human peripheral lung tissue is described. The method involves homogenization of tissue in 0.25m sucrose-buffered medium followed by differential and sucrose density gradient centrifugation. Enzymatic and morphological characterization of the plasma membrane fraction revealed minimal contamination by nonplasma membrane fragments. The isolated plasma membranes showed an 18-fold purification of 5′-nucleotidase activity compared to the original homogenate. Electronmicroscopic studies of the plasma membrane fraction revealed the presence of small membrane vesicles having a trilaminar membrane structure. To further examine the purity of the plasma membrane preparation, the binding of the H1 receptor antagonist,3H pyrilamine, to the plasma membrane-enriched fraction was compared to the binding to crude membrane preparations. Both the plasma membrane-enriched fraction and the crude membrane preparation had similar Kd's for the histamine antagonist, but the plasma membrane-enriched fraction had a threefold greater binding capacity, reflecting the relative enrichment of plasma membranes of the preparation. Thus, a method has been developed for the isolation of plasma membranes from human peripheral lung which should provide material for a variety of biochemical and pharmacological studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01868524
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  • 2
    Electronic Resource
    Electronic Resource
    Calmodulin-like activity in a mineralising tissue: The rat molar tooth germ (1981)
    Springer
    Calcified tissue international 33 (1981), S. 545-548 
    Details
    ISSN: 1432-0827
    Keywords: calmodulin ; calcium ; mineralisation ; tooth germ
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Calmodulin, a calcium binding protein, has been implicated in the regulation of many calcium-dependent biological processes. Since calcium has an important role in hard tissue genesis, both at intra- and extracellular levels, we anticipate that calcium binding proteins may modulate this process. The present study investigated a mineralising tissue, the rat molar tooth germ, to determine the presence of calmodulin-like activity. A heat-treated cell-free extract of tooth germs provided enhancement of Ca2+-dependent Mg2+-ATPase and 3′:5′-nucleotide phosphodiesterase activity. No enhancement occurred in the absence of calcium or in the presence of trifluoperazine. SDS-polyacrylamide gel electrophoresis of this extract revealed a protein band of approximately 18,000 mol. wt. These findings indicate the presence of calmodulin-like activity in rat molar tooth germs and support the proposal that calcium and calcium binding proteins, in particular calmodulin, have a major regulatory role in the biology of mineralising tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02409487
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  • 3
    Electronic Resource
    Electronic Resource
    Distribution and Variability of Surface Soil Properties at a Regional Scale (2000)
    Springer
    Soil Science Society of America journal 64 (2000), S. 974-982 
    Details
    ISSN: 1435-0661
    Keywords: MBC, microbial biomass carbon MEP, Mehlich extractable phosphorus MLRA, Major Land Resource Areas MWD, mean-weight diameter NRCS, Natural Resources Conservation Service NRI, National Resource Inventory PMN, potentially mineralizable nitrogen PSU, primary sampling units TOC, total organic carbon WSA, water stable aggregates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: e transformation resulted in normal distributions for most soil properties and reduced variability two- to threefold. However, a few soil properties remained non-normally distributed. Soil pH may be monitored at the regional scale with a high degree of precision. Small changes in soil C content (3–8% of the regional mean) may be detected using loge transformed total organic C as the indicator. Sampling soil properties as part of the NRI should improve NRCS' ability to monitor soil condition on a regional scale.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/
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  • 4
    Electronic Resource
    Electronic Resource
    An overview of sedimentation on the amazon continental shelf (1984)
    Springer
    Geo-marine letters 4 (1984), S. 207-210 
    Details
    ISSN: 1432-1157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Sedimentological, geochemical, and physical-oceanographic studies of the Brazilian continental shelf near the Amazon River help provide a broad understanding of this major sediment dispersal system. Amazon River sediment accumulates as a subaqueous delta, with the most rapid accumulation (∼10 cm/yr) occurring near the seaward edge of the topset beds and in the foreset beds. Amazon River sediment is dispersed northwestward along the shelf and is transported beyond the Brazilian border. Radiographic studies of sediment cores delineate three sedimentary environments: interbedded mud and sand, faintly laminated mud, and bioturbated mud. The distribution of these environments is a function of proximity to the river mouth and of sediment accumulation rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02281707
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  • 5
    Electronic Resource
    Electronic Resource
    Die Wirkungen der totalen Leberexstirpation (1924)
    Springer
    Reviews of physiology, biochemistry and pharmacology 23 (1924), S. 212-273 
    Details
    ISSN: 1617-5786
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Zusammenfassung Kurz zusammengefasst sind die wichtigsten, hier niedergelegten Tatsachen folgende: Es wurde eine Methode für die totale Entfernung der Leber bei Hunden ausgebildet, welche frei von den meisten Fehlerquellen ist, die früheren Exstirpationsmethoden des Organs bei Säugetieren anhaften. Es wurde gefunden, dass eine geeignete Einführung von Glukose bei derart operierten Hunden das Leben viele Stunden nach Verlust des gesamten Lebergewebes erhält. Von den vielen an hepatektomierten Tieren gemachten Beobachtungen möchten wir hervorheben, 1. dass die Leber zur Erhaltung des Blutzuckerspiegels absolut wesentlich ist; 2. dass die Leber der wichtigste Faktor, wenn nicht der einzige, bei dem Prozess der Desamidierung und der Harnstoffbildung ist, und 3. dass Bilirubin auch ohne Mitwirkung der Leber gebildet werden kann.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01924578
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  • 6
    Electronic Resource
    Electronic Resource
    The Physical Tourist¶Scientific Travels in the Irish Countryside (2000)
    Springer
    Physics in perspective 2 (2000), S. 313-326 
    Details
    ISSN: 1422-6960
    Keywords: Key words. History of science; Ireland; Rosse Telescope; St. Patrick's College; Birr Demense; Irish National Museum (Galway); Giant's Causeway.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. Newly-prosperous Ireland has a number of sites which the scientific traveller can visit. There are apparatus museums at Birr and Maynooth, and a collection of early apparatus at the physics department of the Irish National University in Galway. The main attraction at Birr is the Rosse Telescope, with its 6-ft diameter speculum, built in the 1840s, and recently refurbished. Travellers to Northern Ireland can see applied geology at the Giant's Causeway.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000160050048
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  • 7
    Electronic Resource
    Electronic Resource
    Chronic exposure of goldfish-derived cell cultures to toxaphene alters the replication of Goldfish Virus-2 (1982)
    Springer
    Bulletin of environmental contamination and toxicology 29 (1982), S. 731-733 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01606114
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  • 8
    Electronic Resource
    Electronic Resource
    Toxicity and intracellular localization of carbaryl and 1-naphthol in cell cultures derived from goldfish (1983)
    Springer
    Bulletin of environmental contamination and toxicology 30 (1983), S. 99-104 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01610105
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  • 9
    Electronic Resource
    Electronic Resource
    Polychlorinated biphenyls in the fish and sediment of the Lower Fox River, Wisconsin (1983)
    Springer
    Bulletin of environmental contamination and toxicology 30 (1983), S. 58-64 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Conclusions Pollution abatement technologies instituted by recycling paper mills have resulted in a decrease in PCBs in final effluents discharged to the Lower Fox River. Concurrent declines in fish PCB body burdens have also been noted. It is not certain, however, whether the resultant decrease in PCB final effluent concentrations is sufficient to protect aquatic life from bioaccumulation of PCBs above an acceptable level. Furthermore, sediment PCB concentrations remain high in previously impacted areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01610099
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  • 10
    Electronic Resource
    Electronic Resource
    Uptake and toxicity of toxaphene to cell cultures derived from goldfish (Carassius auratus) (1982)
    Springer
    Bulletin of environmental contamination and toxicology 29 (1982), S. 68-75 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01606091
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