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  • 1
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    Fluorocarbons reduce myocardial ischemic damage after coronary occlusion (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-03-27
    Description: Open-chest, anesthetized dogs with occlusions of the left anterior descending coronary artery breathed 100 percent oxygen while they were bled to a hematocrit of 25 percent and infused with an approximately equal volume (40 milliliters per kilogram) of fluorocarbon preparation or Ringer solution. Dogs breathing room air and receiving no treatment served as controls. After undergoing 6 hours of coronary occlusion, animals bled and treated with fluorocarbons developed smaller infarctions than those receiving Ringer solution or no treatment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Glogar, D H -- Kloner, R A -- Muller, J -- DeBoer, L W -- Braunwald, E -- Clark, L C Jr -- HL-26215/HL/NHLBI NIH HHS/ -- R01-HL-23140/HL/NHLBI NIH HHS/ -- R01-HL-23526/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1981 Mar 27;211(4489):1439-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7466402" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Constriction ; Coronary Disease/*prevention & control ; Coronary Vessels/physiology ; Dogs ; Fluorocarbons/*therapeutic use ; Myocardial Infarction/pathology/prevention & control ; Myocardium/pathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Rabbit hepatic progesterone 21-hydroxylase exhibits a bimodal distribution of activity (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-08-20
    Description: Progesterone 21-hydroxylase activity varies extensively among liver microsomes prepared from individual New Zealand White (NZW) rabbits. The 21-hydroxylase activities are distributed between two groupings that differ by more than tenfold in mean activity. Both male and female animals are represented in the two groupings. However, females exhibited the higher activity more frequently than males. The 21-hydroxylation of progesterone is catalyzed by one of the liver microsomal cytochrome P-450 isozymes, form 1, and these differences in activity are suggestive of differences in the occurrence of this isozyme among NZW rabbits.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dieter, H H -- Muller-Eberhard, U -- Johnson, E F -- HD04445/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1982 Aug 20;217(4561):741-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6808664" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cytochrome P-450 Enzyme System/metabolism ; Desoxycorticosterone/metabolism ; Female ; Isoenzymes/metabolism ; Liver/*enzymology ; Male ; Microsomes, Liver/metabolism ; NADPH-Ferrihemoprotein Reductase/metabolism ; Progesterone/*metabolism ; Rabbits ; Sex Factors ; Steroid 21-Hydroxylase/*metabolism ; Steroid Hydroxylases/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Synapses between neurons regenerate accurately after destruction of ensheathing glial cells in the leech (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-03-05
    Description: Individual glial cells that ensheathe axons in the central nervous system of the leech were destroyed by intracellular injection of protease. The axons were then severed, and regeneration by particular neurons was studied physiologically and morphologically. Although certain axons sprouted more in the absence of the glial cell, functional synapses were accurately regenerated with normal frequency.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Elliot, E J -- Muller, K J -- NS 15014/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1982 Mar 5;215(4537):1260-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7058345" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Central Nervous System/physiology ; Interneurons/physiology ; Leeches ; Microscopy, Electron ; *Nerve Regeneration ; Neuroglia/*physiology ; Pressoreceptors/physiology ; Synapses/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Sodium appetite in sheep induced by cerebral ventricular infusion of angiotensin: comparison with sodium deficiency (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-10-09
    Description: Intraventricular administration of supraphysiological amounts of renin, nerve growth factor preparation, or angiotensin II greatly increased the consumption of water and hypertonic sodium bicarbonate solution by sheep. These effects were antagonized by intraventricular administration of drugs that prevent the formation of angiotensin II or block its receptors. The fact that these angiotensin-blocking drugs did not change the sodium intake of sodium-deficient sheep challenges the idea that central angiotensin action is involved in sodium appetite due to a deficiency.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Coghlan, J P -- Considine, P J -- Denton, D A -- Fei, D T -- Leksell, L G -- McKinley, M J -- Muller, A F -- Tarjan, E -- Weisinger, R S -- Bradshaw, R A -- New York, N.Y. -- Science. 1981 Oct 9;214(4517):195-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6169149" target="_blank"〉PubMed〈/a〉
    Keywords: Angiotensin II/*pharmacology ; Animals ; Appetite/*drug effects ; Drinking Behavior/drug effects ; Injections, Intraventricular ; Nerve Growth Factors/pharmacology ; Renin/pharmacology ; Saralasin/pharmacology ; Sheep ; Sodium/deficiency/*metabolism ; Teprotide/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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