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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Plant/Operations Progress 1 (1982), S. 85-90 
    ISSN: 0278-4513
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Brookfield, Conn. : Wiley-Blackwell
    Journal of Vinyl and Additive Technology 5 (1983), S. 100-103 
    ISSN: 0193-7197
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Process Engineering, Biotechnology, Nutrition Technology
    Notes: PVC pipe compounds typically contain varying amounts and types of calcium carbonates, paraffin waxes, and other ingredients such as stabilizers, titanium dioxide, calcium stearate, and processing aids. The purpose of this paper is to study the effect of calcium carbonate particle size, coating, and usage level on the properties of PVC pipe. In addition, the effects of varying the paraffin wax level and melt temperature will be explored. The paper describes these effects as a function of both impact strength and stress-rupture regression. Based on these results, a series of recommendations on type and usage level of the calcium carbonates and paraffin waxes, and processing conditions for the compound will be developed for use in guiding the pipe manufacturer towards producing PVC pipe that is both performance-oriented and cost-effective.
    Additional Material: 7 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 18 (1983), S. 494-496 
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 24 (1984), S. 131-152 
    ISSN: 0730-2312
    Keywords: liver cell (hepatocyte) ; very low density lipoprotein (VLDL) ; apolipoproteins ; glycerolipids ; metabolism ; assembly ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Very low density lipoprotein (VLDL) is the major vehicle in the plasma which carries triacylglycerol synthesized in the liver to peripheral tissues for utilization. Estrogen-induced chick parenchymal liver cells (hepatocytes) synthesize and secrete large amounts of VLDL. These cells, in a primary monolayer culture system developed in this laboratory, have been employed to study the operative and regulatory aspects of VLDL synthesis, assembly, and secretion. Some 10 min are required for the translation of the principle VLDL protein constituent, apolipoprotein B, and 30-35 min are required for the two newly translated chick VLDL apolipoproteins, apolipoprotein B and apolipoprotein II, to be secreted. Apolipoprotein B is synthesized on membrane-bound polysomes as a contiguous polypeptide chain of 350K molecular weight (MW) and is not assembled posttranslationally from smaller-peptide precursors. Translocation of puromycin-discharged apolipoprotein B nascent chains into the endoplasmic reticulum lumen and their subsequent secretion are independent of both ongoing protein synthesis and the attachment of the nascent peptides to ribosomes. Apolipoprotein B nascent chains discharged by puromycin assemble with glycerolipid (mainly triacylglycerol) and are secreted as immunoprecipitable VLDL. Core oligosaccharides are added to the apolipoprotein B nascent chain co-translationally in at least two stages, at molecular weights of ∼ 120K and ∼ 280K. Inhibition of N-linked glycosylation of apolipoprotein B with tunicamycin affects neither the assembly of glycerolipids into VLDL nor the secretion of the VLDL particle, indicating that aglyco-apolipoprotein B can serve as a functional component for VLDL assembly and secretion. Active synthesis of the VLDL apolipoproteins is required, however, for glycerolipid assembly into VLDL and secretion from the hepatocyte. The differential kinetics with which newly synthesized apolipoproteins and glycerolipids are secreted as VLDL and the timing of the effects of protein-synthesis inhibitors on their secretion indicate that VLDL constituents are assembled sequentially in the intact liver cell. The bulk of the VLDL triacylglycerol and some VLDL phosphoglyceride is introduced early in the secretory pathway proximal, yet subsequent to apopeptide synthesis, while a significant fraction of VLDL phosphoglyceride associates with the resulting triacylglycerol-rich lipid-protein complexes just prior to their secretion as mature VLDL. Within the context of current models for VLDL structure, the late assembly of phosphoglyceride into VLDL is taken to represent a surface maturation of the nascent VLDL particle.
    Additional Material: 8 Ill.
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 121 (1984), S. 193-198 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 16 (1984), S. 1357-1370 
    ISSN: 0538-8066
    Keywords: Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The gas-phase reaction of CF3 with HCN has been examined over a wide conversion range using CF3I as a thermal and photolytic source of radicals. Quantitative and qualitative results show a significant increase of the specific rate constant for the hydrogen abstraction reaction relative to CF3 recombination when reaction is carried out under ultraviolet irradiation. This “extra” formation of the reaction product, CF3H, has been assigned to the participation of iodine in this system through the formation of a (I-HCN) intermediate. Arrhenius parameters obtained for the addition mechanism of I to HCN do not seem to conform to a single reaction step, on the contrary, they correspond to a more complex reaction scheme.
    Additional Material: 8 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 9 (1980), S. 134-136 
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Rates of deuterium exchange of the 8-CH groups of 5′-rGMP and cGMP in D2O solutions (KH) are compared with rates of protium exchange of the 8-CD groups of the same compounds in H2O solutions (KD). The ratio of the two rate constants (kH/kD) defines an isotope effect which is a combination of primary kinetic and solvent isotope effects, the former predominating. The net isotope effect was measured by Raman spectrophotometry over the temperature range 30-80°C. The Arrhenius activation energies (Ea) and pre-exponential frequency factors (A) were also determined. The average values of kH/kD are 1.82 ± 0.15 for 5′-rGMP and 1.43 ± 0.06 for cGMP. The relatively small kinetic isotope effects are indicative typically of an unsymmetrical transition state. The ratio EaH/EaD is unity in both compounds, indicating an early or reactant-like transition state. The present data are consistent with, and extend the range of, the Bell-Goodall curve relating log (kH/kD) to ΔpK of the two acid-base systems involved in the proton transfer during the rate-determining step.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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