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  • 2015-2019  (378)
  • 1980-1984  (46)
  • 1965-1969  (35)
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  • 1
    Publication Date: 2015-10-31
    Description: Soil moisture–atmosphere feedbacks play an important role in the regional climate over many regions worldwide, not only for the mean climate but also for extreme events. Several studies have shown that the extent and severity of droughts and heat waves can be significantly impacted by dry or wet soil moisture conditions. To date, the impact of soil moisture on heavy rainfall events has been less frequently investigated. Thus, we consider the role of soil moisture in the formation of heavy rainfall using the Oder flood event in July 1997 as an example. Here, we used the regional climate model CCLM as an uncoupled standalone model and the coupled COSTRICE system, where CCLM is coupled with an ocean and a sea ice model over the Baltic and North Sea regions. The results from climate simulations over Europe show that the coupled model can capture the second phase (18–20 July) of heavy rainfall that led to the Oder flood, while the uncoupled model does not. Sensitivity experiments demonstrate that the better performance of the coupled model can be attributed to the simulated soil moisture conditions in July 1997 in Central Europe, which were wetter for the coupled model than for the uncoupled model. This finding indicates that the soil moisture preceding the event significantly impacted the generation of heavy rainfall in this second phase. The better simulation in the coupled model also implies the added value that the atmosphere–ocean coupling has on the simulation of this specific extreme event. As none of the model versions captured the first phase (4–8 July), despite the differences in soil moisture, it can be concluded that the importance of soil moisture for the generation of heavy rainfall events strongly depends on the event and the general circulation pattern associated with it. Keywords: climate modelling, dynamic meteorology, climate dynamics (Published: 30 October 2015) Citation: Tellus A 2015, 67, 28661, http://dx.doi.org/10.3402/tellusa.v67.28661
    Print ISSN: 0280-6495
    Electronic ISSN: 1600-0870
    Topics: Geography , Geosciences , Physics
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  • 2
    Publication Date: 2015-10-30
    Print ISSN: 0280-6495
    Electronic ISSN: 1600-0870
    Topics: Geography , Geosciences , Physics
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  • 3
    Publication Date: 2019-10-04
    Description: Ovarian cancer is the leading cause of death among gynecological cancers, but is poorly amenable to preoperative diagnosis. In this study, we investigate the feasibility of “optical biopsy,” using high-optical-resolution photoacoustic microscopy (OR-PAM) to quantify the microvasculature of ovarian and fallopian tube tissue. The technique is demonstrated using excised human ovary and fallopian tube specimens imaged immediately after surgery. Quantitative parameters are derived using Amira software. The parameters include three-dimensional vascular segment count, total volume and length, which are associated with tumor angiogenesis. Qualitative results of OR-PAM demonstrate that malignant ovarian tissue has larger and more tortuous blood vessels as well as smaller vessels of different sizes, while benign and normal ovarian tissue has smaller vessels of uniform size. Quantitative analysis shows that malignant ovaries have greater tumor vessel volume, length and number of segments, as compared with benign and normal ovaries. The vascular pattern of benign fallopian tube is different than that of benign ovarian tissue. Our initial results demonstrate the potential of OR-PAM as an imaging tool for fast assessment of ovarian tissue and fallopian tube and could avoid unnecessary surgery if the risk of the examined ovary is extremely low.
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Springer Nature
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 71 (1967), S. 2694-2699 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Current genetics 5 (1982), S. 245-249 
    ISSN: 1432-0983
    Keywords: Hybrid variegation ; Pelargonium ; Extranuclear inheritance ; Plastid DNA ; Restriction patterns
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary. 1) The genetical and cytological analysis of crosses between the wild-type form ‘Roseum’ of Pelargonium zonale (L.) L 'Herit. ex Ait. and the hybrid species Pelargonium zonale hort. ‘Stadt Bern’' revealed the occurrence of hybrid variegation in the genus Pelargonium 2) The plastids in the green-white variegated plants were sorted out in the quick apical way characteristic for Pelargonium chimera. Six types of periclinal chimeras could be observed. 3) The DNAs of the two different plastomes can be distinguished by restriction endonuclease analysis with EcoRl and BamHI. 4) The differences in the cleavage patterns allowed a detailed description of the process of sorting out of the two parental plastids types within the variegated hybrids on the level of their plastid DNA. In all cases observed the cleavage pattern of ‘Roseum’ plastid DNA was found in the green tissue and the pattern of ‘Stadt Bern’ plastid DNA in the white tissue. 5) From these results we draw the conclusion that there is a disharmony between the F1-hybrid nucleus and the plastome of Stadt Bern', which blocks the normal differentiation of ‘Stadt Bern’ plastids.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 81 (1984), S. 457-464 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Studies were carried out to define antigenic characteristics of the rabbit renal collecting duct. Renal papillae of adult rabbits were homogenized, centrifuged, and the 600×g pellet was extracted with 0.5% Triton X-100 in the presence of 1 M NaCl. The crude extract was fractionated on an anion exchange column (DEAE cellulose). A fraction enriched in acidic proteins that co-purified with a radioactive 150 kd glycoprotein from cultured collecting duct cells (Minuth 1982), was used for immunization of guinea pigs. The antiserum shows the following characteristics as revealed by indirect immunofluorescence on the rabbit kidney: 1) Among all tubular epithelial cells only principal cells of the collecting duct and the connecting tubule cell show immunoreactivity. 2) The antiserum decorates the epithelial-interstitial interface of the whole collecting duct as well as of connecting tubule and thick ascending limb of Henle's loop. 3) There is immunoreactivity of interstitial fibers throughout the kidney. 4) Epithelial cells in a variety of other organs in rabbit did not react with the antiserum. Our data demonstrate an antigenic distinction of both, the connecting tubule cell and the principal cell, discriminating these cells from other tubular epithelial cells including the intercalated cells of the collecting duct system. Furthermore, our findings point to a heterogeneity along the distal nephron with respect to the constituents of the epithelial-interstitial interface.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 22 (1966), S. 385-386 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The turnover of α2-macroglobulins was measured by quantitative precipitation of the I131-marked protein, using a specific antiserum. In 6 normal persons, the half-life was found to be between 192 and 267 h. The catabolic rates in relation to the intravascular pool range between 437 and 703 mg/day
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 25 (1969), S. 1298-1300 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Es hat sich gezeigt, dass Dimethyl-Sulfoxid (DMSO) die RNA-Synthese in Sarkom 180 Tumorzellen in vitro hemmt. In 15% DMSO betrug die Syntheserate nur 7% der Kontrolle. Diese Hemmung war leicht reversibel durch einfaches Entfernen des Wirkstoffes durch Auswaschen der Zellen mit Tyrodes-Lösung. Nach Entfernung des DMSO wurde eine leicht erhöhte Aktivität der Synthese beobachtet. Die Angaben wurden mit der Kinetik der Hemmung von DNA-Synthese verglichen und ihre möglichen Beziehungen zu anderen Wirkungen von DMSO beschrieben.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 218 (1968), S. 583-584 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Ashwood-Smith4. found a decreased ability to synthesize protein in mouse bone marrow cells incubated in vitro with concentrations of DMSO greater than 10 per cent (v/v). This inhibition was reversible. Nieuweboer in ref. 5 found that incorporation of leucine into the 10,000gr supernatant of rat ...
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 66 (1983), S. 38-38 
    ISSN: 1432-2242
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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