ISSN:
1420-9071
Keywords:
Streptozotocin
;
diabetes mellitus
;
NAD
;
niacin
;
nicotinamide
;
tryptophan
;
CD-1 mice
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Weanling CD-1 mice were fed either a control diet or a diet deficient in niacin/nicotinamide for one month and then injected i.v. with 60, 80, 100, 120, 140, or 160 mg/kg streptozotocin. Mice on the deficient diet developed a higher incidence of diabetes and more severe hyperglycemia than those on the control diet.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01960237
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