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  • 1985-1989  (287)
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Year
  • 1
    Series available for loan
    Series available for loan
    Trends and concerns spatial sciences (1988)
    Frederictom, N.B. : University of New Brunswick
    Associated volumes
    Details Availability
    Call number: SR 99.0146(136)
    In: Technical report
    Type of Medium: Series available for loan
    Pages: VI, 176 S.
    Series Statement: Technical report / Department of Surveying Engineering 136
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 2
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    Studies of inositol phospholipid-specific phospholipase C (1989)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1989-05-05
    Description: Inositol phospholipid-specific phospholipase C is the enzyme that generates phosphoinositide-derived messenger molecules. Mammalian cells contain at least five immunologically distinct phospholipase C enzymes that appear to be separate gene products. Complete amino acid sequences of four of these isozymes have been established. The overall sequence similarity is surprisingly low for enzymes catalyzing the same chemical reaction: three of them show limited amino acid sequence similarity to each other in two narrow regions, and the fourth enzyme is completely different. The diversity in primary structure together with different regional and cellular expression of the isozymes suggests that each isozyme has a defined function in processing the physiological response of different cell types to a variety of external stimuli and that each is regulated differently.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rhee, S G -- Suh, P G -- Ryu, S H -- Lee, S Y -- New York, N.Y. -- Science. 1989 May 5;244(4904):546-50.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, Bethesda, MD 20892.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2541501" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Cell Membrane/enzymology ; Cytosol/enzymology ; Isoenzymes/*metabolism ; Phosphatidylinositols/*metabolism ; Phosphoinositide Phospholipase C ; Phosphoric Diester Hydrolases/*metabolism ; Phosphorylation ; Second Messenger Systems ; Terminology as Topic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Mathematics achievement of Chinese, Japanese, and American children (1986)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1986-02-14
    Description: American kindergarten children lag behind Japanese children in their understanding of mathematics; by fifth grade they are surpassed by both Japanese and Chinese children. Efforts to isolate bases for these differences involved testing children on other achievement and cognitive tasks, interviewing mothers and teachers, and observing children in their classrooms. Cognitive abilities of children in the three countries are similar, but large differences exist in the children's life in school, the attitudes and beliefs of their mothers, and the involvement of both parents and children in schoolwork.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stevenson, H W -- Lee, S Y -- Stigler, J W -- MH 30567/MH/NIMH NIH HHS/ -- MH 33259/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1986 Feb 14;231(4739):693-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3945803" target="_blank"〉PubMed〈/a〉
    Keywords: Aptitude ; Child ; Child, Preschool ; China/ethnology ; Cognition ; Humans ; Japan/ethnology ; *Mathematics/education ; Parents ; Reading
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells (1988)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1988-12-16
    Description: Mutational inactivation of the retinoblastoma susceptibility (RB) gene has been proposed as a crucial step in the formation of retinoblastoma and other types of human cancer. This hypothesis was tested by introducing, via retroviral-mediated gene transfer, a cloned RB gene into retinoblastoma or osteosarcoma cells that had inactivated endogenous RB genes. Expression of the exogenous RB gene affected cell morphology, growth rate, soft agar colony formation, and tumorigenicity in nude mice. This demonstration of suppression of the neoplastic phenotype by a single gene provides direct evidence for an essential role of the RB gene in tumorigenesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Huang, H J -- Yee, J K -- Shew, J Y -- Chen, P L -- Bookstein, R -- Friedmann, T -- Lee, E Y -- Lee, W H -- EY-05758/EY/NEI NIH HHS/ -- HD-20034/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1988 Dec 16;242(4885):1563-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology, School of Medicine, University of California, San Diego, La Jolla 92093.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3201247" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Division ; DNA, Neoplasm/genetics ; Disease Susceptibility ; Eye Neoplasms/*genetics/pathology ; Humans ; Osteosarcoma/genetics ; Phenotype ; Phosphoproteins/genetics ; Plasmids ; Retinoblastoma/*genetics/pathology ; *Suppression, Genetic ; Transcription, Genetic ; *Transfection ; Tumor Cells, Cultured/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Inactivation of the retinoblastoma susceptibility gene in human breast cancers (1988)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1988-07-08
    Description: Mutational inactivation of the retinoblastoma susceptibility (RB) gene, a recessive cancer gene, has been implicated in the genesis of retinoblastoma and certain other human neoplasms. This gene is now shown to be inactivated in two of nine human breast cancer cell lines examined. The RB gene of one cell line had a homozygous internal duplication of a 5-kilobase region containing exons 5 and 6. The RB messenger RNA transcript was correspondingly lengthened, and its translation was probably terminated prematurely due to a shifted reading frame. The other cell line had a homozygous deletion of the RB gene that removed the entire gene beyond exon 2. The RB gene product, pp110RB, was not detectable in either cell line by immuno-precipitation with specific antibodies. These findings are significant in relation to proposed genetic mechanisms of breast cancer formation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, E Y -- To, H -- Shew, J Y -- Bookstein, R -- Scully, P -- Lee, W H -- CA39537/CA/NCI NIH HHS/ -- EY00278/EY/NEI NIH HHS/ -- EY05758/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1988 Jul 8;241(4862):218-21.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology, School of Medicine, University of California, San Diego, La Jolla 92093.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3388033" target="_blank"〉PubMed〈/a〉
    Keywords: Breast Neoplasms/*genetics ; Chromosomes, Human, Pair 13 ; DNA, Neoplasm/*genetics ; Gene Expression Regulation ; Genes ; Humans ; Retinoblastoma/*genetics ; Tumor Cells, Cultured
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Human retinoblastoma susceptibility gene: cloning, identification, and sequence (1987)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1987-03-13
    Description: Recent evidence indicates the existence of a genetic locus in chromosome region 13q14 that confers susceptibility to retinoblastoma, a cancer of the eye in children. A gene encoding a messenger RNA (mRNA) of 4.6 kilobases (kb), located in the proximity of esterase D, was identified as the retinoblastoma susceptibility (RB) gene on the basis of chromosomal location, homozygous deletion, and tumor-specific alterations in expression. Transcription of this gene was abnormal in six of six retinoblastomas examined: in two tumors, RB mRNA was not detectable, while four others expressed variable quantities of RB mRNA with decreased molecular size of about 4.0 kb. In contrast, full-length RB mRNA was present in human fetal retina and placenta, and in other tumors such as neuroblastoma and medulloblastoma. DNA from retinoblastoma cells had a homozygous gene deletion in one case and hemizygous deletion in another case, while the remainder were not grossly different from normal human control DNA. The gene contains at least 12 exons distributed in a region of over 100 kb. Sequence analysis of complementary DNA clones yielded a single long open reading frame that could encode a hypothetical protein of 816 amino acids. A computer-assisted search of a protein sequence database revealed no closely related proteins. Features of the predicted amino acid sequence include potential metal-binding domains similar to those found in nucleic acid-binding proteins. These results provide a framework for further study of recessive genetic mechanisms in human cancers.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, W H -- Bookstein, R -- Hong, F -- Young, L J -- Shew, J Y -- Lee, E Y -- New York, N.Y. -- Science. 1987 Mar 13;235(4794):1394-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3823889" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Base Sequence ; *Carboxylesterase ; Carboxylic Ester Hydrolases/genetics ; Chromosome Mapping ; *Chromosomes, Human, Pair 13 ; *Cloning, Molecular ; DNA/genetics ; Eye Neoplasms/*genetics ; Female ; Homozygote ; Humans ; Nucleic Acid Hybridization ; Placenta/analysis ; Pregnancy ; RNA, Messenger/genetics ; Retina/analysis/embryology ; Retinoblastoma/*genetics ; Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Petroleum Geology of Principal Sedimentary Basins in Eastern China: ABSTRACT (1986)
    American Association of Petroleum Geologists
    Details
    Publication Date: 1986-01-01
    Print ISSN: 0149-1423
    Electronic ISSN: 1943-2674
    Topics: Geosciences
    Published by American Association of Petroleum Geologists
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  • 8
    Electronic Resource
    Electronic Resource
    Isolation and characterization of the major mannose-binding protein in chicken serum (1985)
    s.l. : American Chemical Society
    Biochemistry 24 (1985), S. 5932-5938 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00342a036
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  • 9
    Electronic Resource
    Electronic Resource
    Oxidative degradation of organic acid conjugated with sulfite oxidation in flue gas desulfurization: products, kinetics, and mechanism (1987)
    s.l. : American Chemical Society
    Environmental science & technology 21 (1987), S. 266-272 
    Details
    ISSN: 1520-5851
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/es00157a007
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  • 10
    Electronic Resource
    Electronic Resource
    The kinetics of photoinhibition and its recovery in the red alga Porphyridium cruentum (1988)
    Springer
    Archives of microbiology 150 (1988), S. 529-533 
    Details
    ISSN: 1432-072X
    Keywords: Photosynthesis ; O2 evolution ; Photoinhibition ; Recovery ; Porphyridium cruentum ; Biomass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract When Porphyridium cruentum cells were illuminated with high fluence rate between 1900 and 4800 μmol photons m-2s-1, a decrease in the photosynthetic activity of the cells was observed. Within the time frame of 20 min, and under the fluence rates studied, the sum of photons to be absorbed by cells (mg of chlorophyll (Chl), sufficient to initiate photoinhibition was calculated to be 9235.8 μmol. The minimal specific light absorption rate to initiate photoinhibition in P. cruentum ranges between 2.29 and 4.26 μmol photons s-1 mg-1 chl.a. There was a linear relationship between the specific rate of photoinhibition and the specific light absorption rate. A photon number of 2.56×104 μmol mg-1 chl.a photoinhibited photosynthesis instantaneously. At 15°C, no photoinhibitory effect was observed at 2300 μmol photons m-2 s-1 even after 45 min of illumination. At the other extreme of 35°C, 84% inhibition of photosynthetic activity was observed within 10 min of exposure to 2300 μmol photons m-2 s-1. Between 20 and 30°C, the photoinhibitory effect was comparable. Photoinhibited P. cruentum cells recovered readily when transferred to low light (90 μmol photons m-2 s-1) and darkness, and the specific rate of recovery was independent of the light intensity to which the cells were exposed, during the photoinhibitory treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00408244
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