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  • LUNAR AND PLANETARY EXPLORATION  (567)
  • Life and Medical Sciences  (518)
  • 1985-1989  (1,085)
  • 1
    Electronic Resource
    Electronic Resource
    Plant tubulin genes: Structure and differential expression during development (1987)
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 8 (1987), S. 435-460 
    Details
    ISSN: 0192-253X
    Keywords: tubulin genes ; microtubules ; Arabidopsis thaliana ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Microtubules are important components of the cytoskeleton of plant cells and play key roles in plant growth and morphogenesis. Recent molecular studies have begun to elucidate the structure and expression of plant genes coding for the major components of microtubules, α- and β-tubulin. Tubulin amino acid sequences deduced from the DNA sequences of eight higher plant tubulin genes are 79-87% homologous with constitutively expressed mammalian tubulins. The genome of the model plant system Arabidopsis thaliana contains four dispersed α-tubulin sequences and at least seven β-tubulin sequences, only two of which appear to be linked. Of the five A. thaliana genes whose expression has been analyzed, the transcripts of one α-tubulin and one β-tubulin gene are constitutively expressed in roots, leaves, and flowers. A second α-tubulin gene is expressed predominately in flowers; the transcripts of the second and third β-tubulin genes are found predominately in leaves or in roots, respectively.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/dvg.1020080511
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  • 2
    Electronic Resource
    Electronic Resource
    Pharmacological profile of the substituted beta-lactam L-659,286: A member of a new class of human PMN elastase inhibitors (1989)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 39 (1989), S. 47-53 
    Details
    ISSN: 0730-2312
    Keywords: elastase inhibitors ; β-lactams ; lung damage ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Human polymorphonuclear leukocyte elastase (PMN elastase) is inhibited by L-659, 286 (7α-methoxy-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triaz-in-3-yl)thio]methyl]-5-thia-1-aza-6R-bicyclo [4.2.O]oct-2-ene-2-pyrrolidine carboxamide-5,-dioxide) with a Ki of 0.4 μM. This inhibition is time-dependent, rapid, and only slowly reversible, with a t1/2 of 〉 3 days at 25°C. L-659, 286 is also highly selective for PMN elastase, as it does not inhibit thrombin, trypsin, papain, plasmin, chymotrypsin, or cathepsin G. L-659, 286 administered intratracheally inhibits lung damage caused by administration via the same route of human PMN elastase into hamsters. In marmosets, L-659, 286 is cleared from blood very rapidly after an intravenous injection but is recovered in bronchoalveolar lavage fluid for several hours after intratracheal administration.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240390106
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  • 3
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    Observations of the J = 10 manifold of the pure rotational band of phosphine on Saturn (1985)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: Saturn was observed in the vicinity of the J = 10 manifold of the pure rotational band of phosphine on 1984 July 10 and 12 from NASA's Kuiper Airborne Observatory with the facility far-infrared cooled grating spectrometer. On each night observations of the full disk plus rings were made at 4 to 6 discrete wavelengths which selectively sampled the manifold and the adjacent continuum. The previously reported detection of this manifold is confirmed. After subtraction of the flux due to the rings, the data are compared with disk-averaged models of Saturn. It is found that PH3 must be strongly depleted above the thermal inversion (approx. 70 mbar). The best fitting models consistent with other observational constraints indicate that PH3 is significantly depleted at even deeper atmospheric levels (or = 500 mbar), implying an eddy diffusion coefficient for Saturn of 10 to the 4 cm sq/sec.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Icarus (ISSN 0019-1035); 64; 549-556
    Format: text
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    NASA TECHNICAL REPORTS
  • 4
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    Voyager 2 radio science observations of the Uranian system Atmosphere, rings, and satellites (1986)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: The results of preliminary analyses of radio occultation data obtained by Voyager 2 as it passed Uranus are described. The occultations took place between 2-7 deg S latitude and yielded atmospheric temperature profiles between pressure levels of 10-900 mbar, an altitude range of 100 km. The mole fractions of hydrogen and helium in the tropopause were estimated, in conjunction with IR data, to about 0.85 and 0.10-0.20, respectively. Radio signal intensity data indicated the presence of a cloud deck of CH4 ice at a pressure level of 1300 mbar and a temperature of 81 K, implying a CH4 mole fraction of 0.02 at very low altitudes. The ionosphere extended upward, in two levels, to more than 10,000 km altitude. The ring system was different than the one around Saturn and possessed cylindrical substructures. The radio data also permitted mass density estimates for the five major moons, i.e., about 1.40 gr/cu cm, a value which rules out cometary origins.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Science (ISSN 0036-8075); 233; 79-84
    Format: text
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  • 5
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    Apollo 16 regolith breccias - Characterization and evidence for early formation in mega-regolith (1986)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: The Apollo 16 regolith breccias were characterized in terms of petrography, grain-size distribution, porosity, major and trace element composition, noble gas contents, and ferromagnetic resonance properties. Significant variation was found with respect to density and porosity; the more dense breccias displayed substantial shock damage. The breccias resembled the soils in grain-size distribution and in petrological components, though many were found to be compositionally different from the Apollo 16 soils in that a mafic component was lacking. Nearly all breccias showed evidence of irradiation at the lunar surface, and analyses of disaggregated breccias indicated that this irradiation occurred before compaction. The concentration of surface irradiation parameters were far less than those of lunar soils or breccias of other Apollo missions. Observations with respect to the argon isotope ratio and Xe presence have led to the possibility that breccia-surface irradiation occurred as early as four billion years ago, and that most Apollo 16 regolith breccias were not formed from any known Apollo 16 soil.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Journal of Geophysical Research (ISSN 0148-0227); 91; D277-D30
    Format: text
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  • 6
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    Comparison of petrology, grain sizes and surface maturity parameters for Apollo 15 regolith breccias and soils (1985)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: A total of 28 Apollo 15 regolith breccias were analyzed for their petrographic and textural properties and for the surface exposure indices solar noble gases and I (sub s)/Fe 0. Similarities and differences in compositional components and irradiation history were examined between regolith breccias and local, present day soils.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Lunar and Planetary Inst. Papers Presented to the Workshop on tyhe Geology and Petrology of the Apollo 15 Landing Site; p 7-9
    Format: text
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  • 7
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    Electrostatic waves in the magnetosphere of Uranus (1987)
    In:  Other Sources
    Details
    Publication Date: 2019-07-12
    Description: Observations of electrostatic waves in the magnetosphere of Uranus are discussed with attention focused on the Bernstein emissions. The most intense Bernstein waves were observed near the magnetic equator of the planet, even though the tilt of the Uranian magnetic moment is very large relative to the rotational axis. In addition to the Bernstein modes, a number of highly sporadic emissions were detected in the vicinity of the Miranda L shell.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Journal of Geophysical Research (ISSN 0148-0227); 92; 15225-15
    Format: text
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  • 8
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    Apollo 15 regolith breccias - Window to a KREEP regolith (1989)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: The characteristics of 28 regolith breccias returned from the Apollo 15 site have been compared with those of Apollo 15 soils, Apollo 15 rock types, and Apollo 16 regolith breccias. The results suggest that KREEP basalts are not exotic to the site, and that the site is underlain by KREEP basalts which were converted to a KREEP-rich regolith full of small KREEP basalt fragments and KREEP composition glass. A possible implication of the present model is that agglutinate production was not significant in the time interval from 3.9-3.3 Gy.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Lunar and Planetary Science Conference; Mar 14, 1988 - Mar 18, 1988; Houston, TX; United States
    Format: text
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  • 9
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    An upper limit to X-ray emission from Saturn (1986)
    In:  Other Sources
    Details
    Publication Date: 2019-08-27
    Description: X-rays are produced in auroral discharges, and their measurement can serve to characterize the interaction processes responsible for the aurora itself. The existence of auroral activity on Saturn was suggested by the observation of a magnetosphere by Pioneer 11 and confirmed by UV measurements during the Voyager encounters. The detection of X-rays from Jupiter with the Einstein Observatory (HEAO 2) satellite provided the impetus for a subsequent observation of Saturn. No emission was detected. This article presents the upper limit established by the observation and derives an expected emission level assuming X-ray production to be the result of bremsstrahlung from keV electrons precipitating into Saturn's atmosphere. The difference is a factor of 100.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 300; 453-455
    Format: text
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  • 10
    Electronic Resource
    Electronic Resource
    Rapid deformation of “passive” polymorphonuclear leukocytes: The effects of pentoxifylline (1989)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 140 (1989), S. 549-557 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Entry times for spherical (no pseudopods) polymorphonuclear leukocytes (PMNs) into a 4 μm micropipet have been measured as a function of pipet suction pressure (2,500-20,000 dyn/cm2) and concentration of the drug pentoxifylline (PTX, 0.1-10.0 mM). For control cells (0 mM PTX), entry rates (reciprocal entry times) increased almost linearly with increasing suction pressure, indicating a Newtonian-like behavior. With incubation in PTX solutions, entry rate vs. suction pressure became increasingly non-linear, suggesting a shear-thinning effect for the dissipative structure. At a given suction pressure the rate of entry showed a dose-dependent increase with increasing PTX concentration, the effect being most pronounced at high suction pressures (20,000 dyn/cm2). Also, with increasing PTX concentration two other effects were observed: (i) there was a decreased incidence of cells that displayed pseudopodia, and (ii) there was an increased incidence of cells forming hernias and an increased streaming of cell cytoplasm during aspiration. The first observation points to a down-regulation of the cell's functional ability to “activate” in response to surface/chemical stimuli, and the second indicates that both the cortical and cytoskeletal networks are weakened either by disruption and/or reduction in density of the protein polymers. These observations are in line with other recently published experiments which suggest that the rheological effects of pentoxifylline on PMNs may be associated with the state of actin.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041400321
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