ISSN:
1572-879X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A series of sterol esters bearing varying patterns of unsaturation on the nucleus, side chain, and acyl substituent were epoxidized using trans-dioxoruthenium(VI) tetramesitylporphyrin as catalyst and air as source of oxygen. Attack at the steroid nucleus is generally favored, and a high degree of β-stereoselectivity is obtained except for conjugated 5,7 diene systems which yield a ca. 1∶1 mixture of 5,6α and 5,6β epoxides.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00765699
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