ISSN:
1573-0972
Keywords:
Deamination
;
phenylalanine ammonia lyase
;
phenylketonuria
;
Rhodosporidium toruloides
;
Sporidiobolus pararoseus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Abstract Simultaneous depletion of phenylalanine and tyrosine by phenylalanine ammonia lyase is described in a mutual competitive inhibition model. The enzymes obtained fromSporidiobolus pararoseus andRhodosporidium toruloides were charaterized in terms of stability, optimal reaction parameters and kinetic behaviour. Both enzymes followed Michaelis-Menten kinetics with respect to the two amino acids. However, the enzyme fromRhodosporidium toruloides was inhibited by high tyrosine concentrations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01198755
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