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  • 1
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    The role of zinc in selective neuronal death after transient global cerebral ischemia (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-05-17
    Description: Zinc is present in presynaptic nerve terminals throughout the mammalian central nervous system and likely serves as an endogenous signaling substance. However, excessive exposure to extracellular zinc can damage central neurons. After transient forebrain ischemia in rats, chelatable zinc accumulated specifically in degenerating neurons in the hippocampal hilus and CA1, as well as in the cerebral cortex, thalamus, striatum, and amygdala. This accumulation preceded neurodegeneration, which could be prevented by the intraventricular injection of a zinc chelating agent. The toxic influx of zinc may be a key mechanism underlying selective neuronal death after transient global ischemic insults.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Koh, J Y -- Suh, S W -- Gwag, B J -- He, Y Y -- Hsu, C Y -- Choi, D W -- NS30337/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1996 May 17;272(5264):1013-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurology and Center for the Study of Nervous System Injury, Washington University School of Medicine, St. Louis, MO 63110, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8638123" target="_blank"〉PubMed〈/a〉
    Keywords: Aminoquinolines ; Animals ; Brain/metabolism/*pathology ; Cell Death ; Chelating Agents/pharmacology ; Dithizone/pharmacology ; Edetic Acid/pharmacology ; Fluorescent Dyes ; Hippocampus/metabolism/pathology ; Ischemic Attack, Transient/*metabolism/*pathology ; Microscopy, Fluorescence ; *Nerve Degeneration ; Neurons/metabolism/*pathology ; Presynaptic Terminals/metabolism ; Pyramidal Cells/metabolism/pathology ; Rats ; Tosyl Compounds ; Zinc/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
    Electronic Resource
    Electronic Resource
    Frankfurters with Lean Finely Textured Tissue as Affected by Ingredients (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 61 (1996), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Increasing salt concentration from 1.5 to 2.5% increased the emulsion stability of frankfurters made with lean finely textured tissue (LFTT). Sodium tripolyphosphate (STPP) at 0.25% improved stability and texture as well as processing and consumer cooking yields. Kappa (K)-carra-geenan (0.5%) reduced cooking losses and increased firmness. Isolated soy protein (ISP) at 2% also improved product stability and firmness but lowered sensory scores. The effect of ISP on sensory scores was greater for those frankfurters produced from lean finely textured beef than for those with lean finely textured pork. Increasing NaCl concentration or including STPP and K-carrageenan may improve comminuted meat products which contain 50% LFTT substituted for lean meat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1996.tb10978.x
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  • 3
    Electronic Resource
    Electronic Resource
    Functional Protein Components in Lean Finely Textured Tissue from Beef and Pork (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 61 (1996), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: High ionic strength soluble (HIS) proteins, low ionic strength soluble (LIS) proteins, and insoluble (IN) proteins from lean finely textured tissue (LFTT) which was derived from beef and pork trimmings, were evaluated. The IN protein fraction was the major component in LFTT, followed by the LIS protein fraction. The HIS protein fraction from LFTT was present in the smallest quantity. Gels from LFTT had a soft texture and low water retention due to the low level of HIS proteins. SDS-PAGE showed that the major proteins in the LFTT HIS fraction were myosin and actin, but they were present in much smaller quantities than in muscle meats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1996.tb10951.x
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  • 4
    Electronic Resource
    Electronic Resource
    Locking the cavity of a pulsed periodically poled lithium niobate optical parametric oscillator to the wavelength of a continuous-wave injection seeder by an "intensity-dip" method (1999)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 70 (1999), S. 3203-3213 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Injection seeding by a single-mode continuous-wave (cw) laser provides a convenient way to achieve narrowband tunable operation of a laser with a broad spectral gain profile, or of an optical parametric oscillator (OPO). Continuous single-mode tunability of the laser or OPO output usually requires the length of the optical cavity to be controlled as the injection-seeding wavelength is scanned. We report a novel variant on established methods of locking the optical cavity length to the seed wavelength. Our approach takes advantage of the resonance properties of an optical cavity. When the cavity is in resonance with the cw seed radiation, the total intensity of that radiation reflected off the cavity displays a pronounced dip; this intensity dip can be used as a locking signal to reset the cavity length piezoelectrically during each interval between the pump pulses that excite the laser or OPO. Our active cavity-locking scheme is realized in the case of a ring-cavity OPO, incorporating periodically poled lithium niobate (PPLN), pumped at 1.064 μm by a single-mode pulsed Nd:yttrium–aluminum–garnet laser and injection-seeded at its signal wavelength by a 1.55 μm single-mode tunable diode laser. The coherent infrared output of this injection-seeded PPLN OPO is shown to be continuously tunable, with an optical bandwidth of ∼130 MHz (0.0045 cm−1) and excellent spatial beam quality. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1149895
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  • 5
    Electronic Resource
    Electronic Resource
    Synthesis of epothilones A and B in solid and solution phase (1997)
    [s.l.] : Nature Publishing Group
    Nature 387 (1997), S. 268-272 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The strategy for the solid-phase synthesis of epothilone A (1) was based on the retro synthetic analysis indicated in Fig. 1 (refs 5, 13). Thus, it was anticipated that the three requisite fragments (5-7), one on a solid support (7), would be coupled together sequentially through an aldol reaction, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/387268a0
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  • 6
    Electronic Resource
    Electronic Resource
    Electronic conductivity of hydrogenated nanocrystalline silicon films (1995)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 3945-3948 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A heteroquantum-dots (HQD) model for hydrogenated nanocrystalline silicon films (nc-Si:H) is proposed. The main features of our model are as follows. (i) the nanocrystalline grains and the amorphous counterparts in which they are embedded have very different band gap and band structures. As a result, they form heterojunctionlike structures in the interface regions, where the band offset effects dramatically reduce the activation energy and the grains act like quantum dots. (ii) In the presence of an external field, the activated electrons in the quantum dots conduct via quantum tunneling through the interface barriers. By means of the HQD model, we have identified the conduction of nc-Si:H as a thermal-assisted tunneling process. Our results show that there are two distinct regimes for the conductivity of nc-Si:H: (i) the low-temperature regime, where there is a simple activation energy ΔE; (ii) the high-temperature regime, where ΔE is effectively enhanced by the temperature effect of the electronic tunneling in the nanoscale particles. The theory is in good agreement with the experiments. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.359914
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  • 7
    Electronic Resource
    Electronic Resource
    Visible light emission from thin films containing Si, O, N, and H (1995)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 4020-4030 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report the fabrication, chemical, optical, and photoluminescence characterization of amorphous silicon-rich oxynitride (SiOxNy:H) thin films by plasma-enhanced chemical-vapor deposition. The film compositions were followed by changes in the refractive index. X-ray photoelectron and Fourier transform infrared spectroscopy indicate that the chemical composition is dominated by silicon suboxide bonding with N present as a significant impurity. A broad tunable photoluminescence (PL) emission is visible at room temperature with a quantum efficiency of 0.011% at peak energies to 3.15 eV. The radiative lifetimes are less than 10 ns, and there is nearly no temperature dependence of the PL intensity down to 80 K. Ex situ annealing at temperatures above 850 °C results in an increase in PL efficiency by nearly three orders of magnitude, and the PL intensity is independent of the annealing ambient. The PL results are remarkably similar to literature results in oxidized porous silicon and oxidized nanocrystalline Si thin films, and suggest that the radiative center is due to the defect structure in the silicon suboxide moiety. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.359925
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  • 8
    Electronic Resource
    Electronic Resource
    Phonon mode study of Si nanocrystals using micro-Raman spectroscopy (1995)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 6705-6708 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: First-order Raman spectra of hydrogenated nanocrystalline silicon (nc:Si:H) films show unexpected features in their optical vibrational modes for crystallites with sizes ranging from 2 to 6 nm. Two size-dependent spectral regions, one with the stronger intensity peaking at 505–509 cm−1 and another a shoulder-like band between 512 and 517 cm−1, are clearly identified using a detailed line-shape analysis and the strong phonon confinement model. The strong size dependence of the relative integrated intensities of the two bands suggests that the modification of the vibrational spectra can be attributed to an effect induced by the atomic vibrations from the near-surface region of the nanocrystals. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.360494
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  • 9
    Electronic Resource
    Electronic Resource
    Measurement of low energy ion tracks in CR-39 plastic with an atomic force microscope (1995)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 4575-4582 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We demonstrate that an atomic force microscope allows one to measure the detailed geometry of etch pits due to heavy ions with kinetic energies of 1−10 keV/amu at small distance scales registered in the nuclear track detector CR-39 plastic. With a typical range of a few hundred nm and an etch pit depth on the order of a few tens of nm, these ion tracks cannot be measured using conventional methods. With the technique developed in this work one is able to study the response of CR-39 plastic to particles at low ionization rates by precise measurements of low energy ion tracks. Among other applications, of particular interest is to explore the response of CR-39 in the regime in which nuclear stopping is comparable to electronic stopping. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1145291
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  • 10
    Electronic Resource
    Electronic Resource
    High moment soft magnetic FeTiN thin films for recording head materials (1999)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 3745-3748 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Soft magnetic properties and thermal stability of Fe–Ti–N alloys films have been investigated. Thin films with composition in the range of 8–10 at. % Ti, 10.5–14 at. % N, and balance Fe were prepared by reactive sputtering method. The films exhibit good soft magnetic properties in the as-deposited condition without any post heat treatment, e.g., low coercivity Hc∼1.5 Oe, high permeability μ∼3200 at 1 MHz and very high saturation magnetization 4πMs∼24 kG. The thermal stability of these films was also found to be good, e.g., Hc was less than 2 Oe, and 4πMs was higher than 23 kG for the films annealed up to 500 °C. The high electrical resistivity ρ∼100 μ Ω cm of the films can minimize the eddy current loss in the high frequency applications. The combination of high 4πMs and relatively high anisotropy field Ha∼10 Oe in the film is conductive to the suppression of the undesirable ferromagnetic resonance interfere up to the GHz frequency range. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.369742
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