ISSN:
1546-1718
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] Of the five known forms of mammalian FMO12, FMO3 represents the major hepatic FMO in humans9,10 and displays a distinct substrate preference for tertiary amines11. As TMA is cleared substantially by hepatic first-pass metabolism13, FMO3 is thus likely to catalyze most TMA N-oxidation in vivo. The ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/ng1297-491
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