ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
An efficient route for an alternative synthesis of gibberllin A1 from gibberellin A3 is described. Based on iodolactonisation the method provides access to gibberellin A1 labeled by deuterium with both high incorporation of the isotope and high stereoselectity at the positions 1β and 2α. The additional deuterium labeling at C-17 was introduced via the corresponding 16-norketone resulting in [1β,2α,17,17-D4] gibberellin A1.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19973390178
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