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  • 1
    Publication Date: 1998-03-07
    Description: The spindle checkpoint regulates the cell division cycle by keeping cells with defective spindles from leaving mitosis. In the two-hybrid system, three proteins that are components of the checkpoint, Mad1, Mad2, and Mad3, were shown to interact with Cdc20, a protein required for exit from mitosis. Mad2 and Mad3 coprecipitated with Cdc20 at all stages of the cell cycle. The binding of Mad2 depended on Mad1 and that of Mad3 on Mad1 and Mad2. Overexpression of Cdc20 allowed cells with a depolymerized spindle or damaged DNA to leave mitosis but did not overcome the arrest caused by unreplicated DNA. Mutants in Cdc20 that were resistant to the spindle checkpoint no longer bound Mad proteins, suggesting that Cdc20 is the target of the spindle checkpoint.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hwang, L H -- Lau, L F -- Smith, D L -- Mistrot, C A -- Hardwick, K G -- Hwang, E S -- Amon, A -- Murray, A W -- New York, N.Y. -- Science. 1998 Feb 13;279(5353):1041-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physiology, University of California at San Francisco, San Francisco, CA 94143-0444, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9461437" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Anaphase ; Anaphase-Promoting Complex-Cyclosome ; Cadherins ; Calcium-Binding Proteins/metabolism ; *Carrier Proteins ; Cdc20 Proteins ; Cdh1 Proteins ; Cell Cycle Proteins/chemistry/genetics/*metabolism ; DNA Damage ; DNA Replication ; Fungal Proteins/chemistry/*metabolism ; Ligases/metabolism ; Mad2 Proteins ; *Mitosis ; Molecular Sequence Data ; Mutation ; Nuclear Proteins/metabolism ; Phosphoproteins/metabolism ; *Repressor Proteins ; Saccharomyces cerevisiae/*cytology/*metabolism ; *Saccharomyces cerevisiae Proteins ; Spindle Apparatus/*metabolism ; *Ubiquitin-Protein Ligase Complexes ; Ubiquitin-Protein Ligases
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 22 (1998), S. 529-546 
    ISSN: 1432-0541
    Keywords: Key words. Divide-and-conquer, Minimum Euclidean matching, Mellin transform, Exponential sums, van der Corput's method.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract. We examine in detail the asymptotic behaviors of the number of comparisons used in Batcher's sorting algorithm and a quantity arising in analyzing the rectangle heuristic for finding minimum Euclidean matching due to Supowit and Reingold. We put forth methods (elementary and analytic) for computing the Fourier coefficients of periodic functions appearing in the asymptotic expansions of these quantities. The methods consist of the approach by Flajolet and Golin for divide-and-conquer recurrences and van der Corput's method from analytic number theory for exponential sums.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A detailed study of doped LaMnO3 with fixed carrier concentration has revealed a direct relationship between the Curie temperature Tc and the average ionic radius of the La site 〈rA〉, which is varied by substituting rare earths of different ionic radii for La. With decreasing 〈rA〉 magnetic order and significant magnetoresistance occur at lower temperatures with increasing temperature hysteresis, and the magnitude of the magnetoresistance increases dramatically. The predominant structural effect of decreasing 〈rA〉 is to decrease the Mn–O–Mn bond angle, which is accompanied by slight variations in the Mn–O bond distance. These results demonstrate that the notion of "double exchange'' must be generalized to include changes in the Mn–Mn electronic hopping element as a result of microstructural changes induced by composition, temperature and pressure variations. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 77 (1995), S. 6542-6548 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The microstructures of low-temperature polycrystalline silicon grown both on SiO2 and Corning 7059 glass substrate are presented. The silicon was deposited by the hydrogen dilution method using electron-cyclotron-resonance chemical-vapor deposition at 250 °C without any thermal annealing. The hydrogen dilution ratios were varied from 90% to 99%. Transmission electron microscopy images, Raman shift spectra, and x-ray-diffraction (XRD) patterns of the films were obtained. The maximum grain size was about 1 μm and the crystalline fraction which was characterized from Raman shift spectra was near 100%. From the XRD patterns 〈111〉- and 〈110〉-oriented crystalline silicon grains were clearly present in the polycrystalline silicon films. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 5336-5336 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A detailed study of doped LaMnO3 with a fixed carrier concentration has revealed a rich phase diagram as a function of the average ionic radius of the La site 〈rA〉. The transition temperature TC, from a high-temperature paramagnetic insulator to a low-temperature ferromagnetic metal, decreases rapidly with reduced 〈rA〉. Systematic trends in the magnetotransport properties and the spin dynamics are strongly correlated with the proximity of the zero-temperature insulator phase. The general structure of this phase diagram can be understood by considering the role of static and dynamic distortions of the MnO6 octahedra and their evolution as a function of 〈rA〉.© 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 4953-4953 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have fabricated and studied the structure and magnetic properties of high quality single crystalline (La0.7Ca0.3)MnO3 and (La0.7Ba0.3)MnO3 films. Films were grown on SrTiO3 as well as LaAlO3 substrates. (La0.7Ca0.3)MnO3 and (La0.7Ba0.3)MnO3 films grown on SrTiO3 exhibit excellent crystallinity and magnetic properties while those grown on LaAlO3 show mediocre structural and magnetic properties. These differences indicate the importance of lattice match and structural similarity between the film and the substrate. X-ray and Rutherford backscattering analysis provide a consistent picture of the structural properties of these doped manganite films. These films enable us to investigate the crystal anisotropy using vibrating sample magnetometry and torque magnetometry. Multilayers composed of manganite layers with different dopants (e.g., calcium and barium dopants) also have excellent structural properties since there is minimal strain at the interfaces. Such isostructural single crystalline multilayers are essential for investigating exchange coupling of the doped manganites.© 1997 American Institute of Physics.
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 79 (1996), S. 7510-7513 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We present a rigorous and convenient approach for estimating the resonant states from the pole of the scattering matrix (reflection coefficient) in the complex energy plane and for determining the resonant tunneling time from the spacing of the energy doublets arising at resonance. The numerical calculation is much faster than numerical integration of the Schrödinger equation. When we apply this method to the coupling of two identical quantum wells, it is shown that the usual and naive estimation of resonant tunneling time through the Wentzel-Kramers-Brillouin method is invalid. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 74 (1999), S. 2316-2318 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Observation of sequentially adjustable, intense, and stable emissions at room temperature from amorphous silicon-rich oxide thin films without any thermal annealing is reported. Hydrogenated amorphous silicon-rich oxide (SiOx:N:H, 0〈x〈2) thin films were deposited by plasma-enhanced chemical-vapor deposition with a mixture of 5% silane in argon and nitrous oxide gases. The strong naked-eye-seeing photoluminescence (blue–white–orange) could be adjusted by changing the process gases flow rate ratio Γ (=[SiH4]/[N2O]). The degree of silicon richness was determined from secondary ion mass spectrometry. The microstructure-bonding configuration was examined by Fourier transform infrared spectroscopy. The implications of these studies for understanding the origins of silicon-based luminescence are discussed. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 68 (1996), S. 3494-3496 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report significant improvement in the magnetoresistive (MR) response of perovskite manganites for small applied fields by the use of heterostructures with soft ferromagnets. At room temperature, a 5900-fold enhancement of the MR response at 10 Oe in La2/3Ca1/3MnO3 has been achieved using (Mn,Zn)Fe2O4 as the soft ferromagnet. By utilizing soft ferromagnets with various magnetic properties, this technique allows for enormous flexibility in "designing'' a desired MR response for the manganites, particularly in low fields. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 3967-3967 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have recently studied the spin dynamics in single crystal perovskite manganites by inelastic neutron scattering. These samples exhibit a transition from a high temperature paramagnetic insulator to a low temperature ferromagnetic metal, leading to large negative magnetoresistance near the simultaneous metal–insulator transition temperature and the Curie temperature TC. By comparing samples with different TC, we discuss systematic trends in the spin dynamics above and below TC. © 1997 American Institute of Physics.
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