ALBERT

Description: The fragmentation of 510 MeV/nucleon iron ions in several thicknesses of polyethylene has been measured. Non-interacting primary beam particles and fragments have been identified and their LETs calculated by measuring ionization energy loss in a stack of silicon detectors. Fluences, normalized to the incident beam intensity and corrected for detector effects, are presented for each fragment charge and target. Histograms of fluence as a function of LET are also presented. Some implications of these data for measurements of the biological effects of heavy ions are discussed.

Description: The results of a Monte Carlo model for calculating fragment fluences and LET spectra are compared to data taken with 600 MeV/nucleon iron ions incident on an accelerator beamline configured for irradiation of biological samples, with no target and with 2, 5 and 8 cm of polyethylene. The model uses a multi-generation nuclear fragmentation code, coupled with a formulation of ionization energy loss based on the Bethe-Bloch equation. In the region where the data are reliable and the experimental acceptance is well understood, many of the features of the experimental spectra are well replicated by the model. To obtain good agreement with the experimental data, the model must allow for at least two generations of fragment production in the target.

Description: Tissue-equivalent proportional counters (TEPCs) have been used to measure energy deposition in simulated volumes of tissue ranging in diameter from 0.1 to 10 microm. There has been some concern that the wall used to define the volume of interest could influence energy deposition within the sensitive volume because it has a density significantly greater than that of the cavity gas. These effects become important for high-velocity heavy ions. Measurements of energy deposition were made for 1 GeV/nucleon iron particles in a TEPC simulating a 1-microm-diameter sphere of tissue. The TEPC was nested within a particle spectrometer that provided identification and flight path of individual particles. Energy deposition was studied as a function of pathlength through the TEPC. Approximately 30% of the energy transfer along trajectories through the center of the detector escapes the sensitive volume. The response of the TEPC, for trajectories through the detector, is always larger than calculations for energy loss in a homogeneous medium. This enhancement is greatest for trajectories near the cavity/wall interface. An integration of the response indicates that charged-particle equilibrium is essentially achieved for a wall thickness of 2.54 mm. However, estimates of the linear energy transfer for the incident particles are influenced by these wall effects.

Description: We report beam characterization and dosimetric measurements made using a 56Fe beam extracted from the Brookhaven National Laboratory Alternating Gradient Synchrotron (AGS) with a kinetic energy of 1087 MeV/nucleon. The measurements reveal that the depth-dose distribution of this beam differs significantly from that obtained with a 600 MeV/nucleon iron beam used in several earlier radiobiology experiments at the Lawrence Berkeley National Laboratory's BEVALAC. We present detailed measurements of beam parameters relevant for radiobiology, including track- and dose-averaged linear energy transfer (LET), fragment composition and LET spectra measured behind sample holders used in irradiations of biological samples. We also report measurements of fluence behind three depths (1.94, 4.68 and 9.35 g cm(-2)) of polyethylene targets with the 1087 MeV/nucleon beam, and behind 1.94 g cm(-2) of polyethylene with a 610 MeV/nucleon beam delivered by the AGS. These results are compared to earlier measurements with the 600 MeV/nucleon beam at the BEVALAC.

Description: The use of Green's function has played a fundamental role in transport calculations for high-charge high-energy (HZE) ions. Two recent developments have greatly advanced the practical aspects of implementation of these methods. The first was the formulation of a closed-form solution as a multiple fragmentation perturbation series. The second was the effective summation of the closed-form solution through nonperturbative techniques. The nonperturbative methods have been recently extended to an inhomogeneous, two-layer transport media to simulate the lead scattering foil present in the Lawrence Berkeley Laboratories (LBL) biomedical beam line used for cancer therapy. Such inhomogeneous codes are necessary for astronaut shielding in space. The transport codes utilize the Langley Research Center atomic and nuclear database. Transport code and database evaluation are performed by comparison with experiments performed at the LBL Bevalac facility using 670 A MeV 20Ne and 600 A MeV 56Fe ion beams. The comparison with a time-of-flight and delta E detector measurement for the 20Ne beam and the plastic nuclear track detectors for 56Fe show agreement up to 35%-40% in water and aluminium targets, respectively.

Description: Liulin, a dosimetry-radiometry system, was developed to satisfy the requirements for active flux and dose rate measurements for the flight of the second Bulgarian cosmonaut in 1988. The system consists of a compact battery-operated silicon solid state detector unit and a read/write microcomputer and telemetry unit. We describe the pre-flight calibrations with charged particles, using radioactive sources and accelerated 170 MeV/nucleon proton and alpha particles at the Dubna, Russia cyclotron. We discuss comparisons with data obtained on Mir with the French-built tissue equivalent LET spectrometer NAUSICAA. Lastly, we describe post-flight calibrations performed with 1 GeV/nucleon 56Fe ions at the Brookhaven National Laboratory AGS accelerator, where the instrument was mounted in tandem with several thin position-sensitive silicon detectors behind a stopping target. The silicon detectors provided an energy spectrum for the surviving charged nuclear fragments for which the flux and absorbed dose were recorded by Liulin.

Description: Neutron fluences were measured from 435 MeV/nucleon Nb ions stopping in a Nb target and 272 MeV/nucleon Nb ions stopping in targets of Nb and Al for neutrons above 20 MeV and at laboratory angles between 3 degrees and 80 degrees. The resultant spectra were integrated over angles to produce neutron energy distributions and over energy to produce neutron angular distributions. The total neutron yields for each system were obtained by integrating over the angular distributions. The angular distributions from all three systems are peaked forward, and the energy distributions from all three systems show an appreciable yield of neutrons with velocities greater than the beam velocity. Comparison of the total neutron yields from the two Nb + Nb systems suggests that the average neutron multiplicity decreases with decreasing projectile energy. Comparison of the total yields from the two 272 MeV/nucleon systems suggests that the total yields show the same dependence on projectile and target mass number as do total inclusive neutron cross sections. The data are compared with Boltzmann-Uehling-Uhlenbeck model calculations.

Description: Trajectory design of the orbit phase of the NEAR mission involves a new process that departs significantly from those procedures used in previous missions. In most cases, a precise spacecraft ephemeris is designed well in advance of arrival at the target body. For NEAR, the uncertainty in the dynamic environment around Eros does not allow the luxury of a precise spacecraft trajectory to be defined in advance. The principal cause of this uncertainty is the limited knowledge oi' the gravity field a,-id rotational state of Eros. As a result, the concept for the NEAR trajectory design is to define a number of rules for satisfying spacecraft, mission, and science constraints, and then apply these rules to various assumptions for the model of Eros. Nominal, high, and low Eros mass models are used for testing the trajectory design strategy and to bracket the ranges of parameter variations that are expected upon arrival at the asteroid. The final design is completed after arrival at Eros and determination of the actual gravity field and rotational state. As a result of the unplanned termination of the deep space rendezvous maneuver on December 20, 1998, the NEAR spacecraft passed within 3830 km of Eros on December 23, 1998. This flyby provided a brief glimpse of Eros, and allowed for a more accurate model of the rotational parameters and gravity field uncertainty. Furthermore, after the termination of the deep space rendezvous burn, contact with the spacecraft was lost and the NEAR spacecraft lost attitude control. During the subsequent gyrations of the spacecraft, hydrazine thruster firings were used to regain attitude control. This unplanned thruster activity used Much of the fuel margin allocated for the orbit phase. Consequently, minimizing fuel consumption is now even more important.

Description: On February 14, 2000, an orbit insertion burn will place NASA's Near Earth Asteroid Rendezvous (NEAR) spacecraft (S/C) into orbit around asteroid 433 Eros. NEAR will initially orbit Eros with distances ranging from 500 to 100 km in order to characterize the shape, gravity and spin of Eros. Once the physical parameters of Eros are determined reasonably well, the plan is to establish an orbit of the NEAR S/C with increasingly lower altitudes as the one year orbital mission progresses while further characterizing the gravity and shape of Eros. Towards the end of the NEAR mission, after the shape, gravity and spin of Eros have been well characterized, the scientific interest of obtaining very close observations (〈 5 km) can be realized. The navigation during this phase relies on a combination of NASA's Deep Space Network (DSN) radio metric tracking, laser ranging (LIDAR) data from the S/C to the surface of Eros, and onboard optical imaging of landmarks on Eros. This paper will provide preliminary plans for mission design and navigation during the last two months of the orbit phase, where several close passes to the surface will be incorporated to enhance the science return. The culmination of these close passes will result in the eventual landing of the S/C on the surface of Eros. Several considerations for these plans are given by Antreasian, et at. [1998]. The objective for the end of the mission will be to land the S/C autonomously using the surface relative information obtained from the onboard LIDAR instrument. The goal will be to soft land the S/C in such a way as to keep it operational. With the use of an onboard LIDAR landing algorithm as discussed by Antreasian et at. [1998], it is believed that the S/C impact velocity can be kept well under 7 m/s which is a requirement for allowing the S/C to remain operational.

Description: In the execution of this proposal, we will first examine current and developing spacecraft materials and evaluate their ability to attenuate adverse biological mutational events in mammalian cell systems and reduce the rate of cancer induction in mice harderian glands as a measure of their protective qualities. The HZETRN code system will be used to generate a database on GCR attenuation in each material. If a third year of funding is granted, the most promising and mission-specific materials will be used to study the impact on mission cost for a typical Mars mission scenario as was planned in our original two year proposal at the original funding level. The most promising candidate materials will be further tested as to their transmission characteristics in Fe and Si ion beams to evaluate the accuracy of the HZETRN transmission factors. Materials deemed critical to mission success may also require testing as well as materials developed by industry for their radiation protective qualities (e.g., Physical Sciences Inc.) A study will be made of designing polymeric materials and composite materials with improved radiation shielding properties as well as the possible improvement of mission-specific materials.