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  • Springer  (23)
  • Wiley  (11)
  • Frankfurt: Campus-Verl.
  • Frontiers Media
  • ZBW - Deutsche Zentralbibliothek für Wirtschaftswissenschaften, Leibniz-Informationszentrum Wirtschaft Kiel, Hamburg
  • 1995-1999  (24)
  • 1990-1994  (10)
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  • 1
    Digitale Medien
    Digitale Medien
    Edge wave and non-trapped modes of the 25 april 1992 Cape Mendocino tsunami (1995)
    Springer
    Pure and applied geophysics 144 (1995), S. 409-426 
    Details
    ISSN: 1420-9136
    Schlagwort(e): Tsunamic ; edge waves ; Cape Mendocino ; Cascadia Subduction Zone ; hazard mitigation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie , Physik
    Notizen: Abstract The 25 April 1992 Cape Mendocino earthquake generated a tsunami characterized by both coastal trapped edge wave and non-trapped tsunami modes that propagated north and south along the U.S. West Coast. Both observed and synthetic time series at Crescent City and North Spit are consistent with the zero-order edge wave mode solution for a semi-infinite sloping beach depth profile. Wave amplitudes at Crescent City were about twice that observed at North Spit, in spite of the fact that the source region was three times farther from Crescent City than North Spit. The largest observed amplitude was due to an edge wave which arrived almost three hours after the initial onset of the tsunami; since such waves are highly localized nearshore, this suggests that the enhanced responsiveness at Crescent City is at least partly due to local dynamic processes. Furthermore, the substantially delayed arrival of this wave, which was generated at the southern end of the Cascadia Subduction Zone, has significant implications for hazard mitigation efforts along the entire U.S. West Coast. Specifically, this study demonstrates that slow-moving but very energetic edge wave modes could be generated by future large tsunamigenic earthquakes in the CSZ, and that these might arrive unexpectedly at coastal communities several hours after the initial tsunami waves have subsided.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00874375
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  • 2
    Digitale Medien
    Digitale Medien
    Protostars and Protoplanetary Disks (1997)
    Springer
    Astrophysics and space science 255 (1997), S. 15-23 
    Details
    ISSN: 1572-946X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1001142213744
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  • 3
    Digitale Medien
    Digitale Medien
    Courseware reviews (1993)
    Springer
    Computers and the humanities 27 (1993), S. 55-71 
    Details
    ISSN: 1572-8412
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik , Medien- und Kommunikationswissenschaften, Kommunikationsdesign
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01830719
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  • 4
    Digitale Medien
    Digitale Medien
    Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5 (1995)
    Springer
    Immunogenetics 43 (1995), S. 88-91 
    Details
    ISSN: 1432-1211
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00186611
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  • 5
    Digitale Medien
    Digitale Medien
    Structure–Metabolism Relationships in the Hydrolysis of Nicotinate Esters by Rat Liver and Brain Subcellular Fractions (1991)
    Springer
    Pharmaceutical research 8 (1991), S. 832-839 
    Details
    ISSN: 1573-904X
    Schlagwort(e): nicotinic acid esters ; carboxylesterases ; subcellular fractions ; structure–metabolism relationships
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract Rat liver and brain subcellular esterase activities toward nicotinic acid esters were studied, under varying conditions, such as pH, organic solvents, protein concentration, duration of incubation, and substrate concentration. Esterases in each subcellular fraction displayed activities that obey Michaelis–Menten kinetics, although subcellular fractions are heterogeneous. The K m values were of the same magnitude, and the V max values were lower in microsomes than in cytosol of the liver. Brain activities normalized to protein concentration, were much lower than liver activities, aromatic nicotinates being the best substrates in both tissues. Myelin and brain mitochondria of nerve-ending and neuroglial origin display esterase activity toward phenyl nicotinate. In contrast to brain esterases, liver esterases appear homogeneous, and esterase activities in both tissues react differently to changes in pH. Qualitative and quantitative structure–metabolism relationships are not suggestive of tissue-specific ester hydrolysis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1015839109449
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  • 6
    Digitale Medien
    Digitale Medien
    Uncoupling Protein 3: Its Possible Biological Role and Mode of Regulation in Rodents and Humans (1999)
    Springer
    Journal of bioenergetics and biomembranes 31 (1999), S. 467-473 
    Details
    ISSN: 1573-6881
    Schlagwort(e): Uncoupling proteins ; fatty acids ; skeletal muscle ; brown adipose tissue ; obesity ; thermogenesis ; gene expression
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Physik
    Notizen: Abstract The recently discovered uncoupling protein 3 (UCP3) is highly homologous to the mitochondrialinner membrane protein UCP1, which generates heat by uncoupling the respiratory chainfrom oxidative phosphorylation. The thermogenic function of UCP1 protects against cold andregulates the energy balance in rodents. We review in vitro studies investigating the uncouplingactivity of UCP3 and in vivo studies, which address UCP3 gene expression in brown adiposetissue and skeletal muscle under various metabolic conditions. The data presented are, for themost, consistent with an uncoupling role for UCP3 in regulatory thermogenesis. We alsodiscuss mediators of UCP3 regulation and propose a potential role for intracellular fatty acidsin the mechanism of UCP3 modulation. Finally, we hypothesize a role for UCP3 in themetabolic adaptation of the mitochondria to the degradation of fatty acids.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1005448423731
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  • 7
    Digitale Medien
    Digitale Medien
    Frame-based representation of philosophical systems using a knowledge engineering tool (1993)
    Springer
    Computers and the humanities 27 (1993), S. 261-275 
    Details
    ISSN: 1572-8412
    Schlagwort(e): conceptual analysis ; knowledge representation ; knowledge engineering ; semantic networks ; text analysis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik , Medien- und Kommunikationswissenschaften, Kommunikationsdesign
    Notizen: Abstract This article addresses the methodological problem of the non-linear representation of philosophical systems in a computerized knowledge base. It is a problem of knowledge representation as defined in the field of artificial intelligence. Instead of a purely theoretical discussion of the issue, we present selected results of a practical experiment which has in itself some theoretical significance. We show how one can represent different philosophies using CODE, a knowledge engineering system developed by artificial intelligence researchers. The hypothesis is that such a computer based representation of philosophical systems can give insight into their conceptual structure. We argue that computer aided text analysis can apply knowledge representation tools and techniques developed in artificial intelligence and we estimate how philosophers as well as knowledge engineers could gain from this cross-fertilization. This paper should be considered as an experiment report on the use of knowledge representation techniques in computer aided text analysis. It is part of a much broader project on the representation of conceptual structures in an expert system. However, we intentionally avoided technical issues related to either Computer Science or History of Philosophy to focus on the benefit to enhance traditional humanistic studies with tools and methods developed in AI on the one hand and the need to develop more appropriate tools on the other.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01830368
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  • 8
    Digitale Medien
    Digitale Medien
    Formation of Extrasolar Giant Planets: Core Accretion or Disk Instability? (1998)
    Springer
    Earth, moon and planets 81 (1998), S. 19-26 
    Details
    ISSN: 1573-0794
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1006370021545
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  • 9
    Digitale Medien
    Digitale Medien
    NASA and the Search for Extrasolar Planets (1998)
    Springer
    Earth, moon and planets 81 (1998), S. 35-38 
    Details
    ISSN: 1573-0794
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1006380328814
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  • 10
    Digitale Medien
    Digitale Medien
    A low molecular weight substance purified from human placenta inhibits cAMP-dependent protein kinase and activates protein kinase C (1997)
    Springer
    Molecular and cellular biochemistry 170 (1997), S. 75-83 
    Details
    ISSN: 1573-4919
    Schlagwort(e): cAMP-dependent protein kinase ; protein kinase C ; phospholipid
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract We have purified from human placenta a low molecular mass substance that inhibits cAMP-dependent protein kinase and activates protein kinase C. This protein kinase regulator was purified in three steps: (1) homogenizing placentas in chloroform/methanol and extracting the regulator into water; (2) eluting a strong anion exchange high performance liquid chromatography (HPLC) column with a quaternary gradient; and (3) eluting a reversed-phase HPLC column with a binary gradient. The regulator was found to be highly purified by HPLC, thin-layer chromatography (TLC) and laser desorption ionization mass spectrometry with a molecular mass of 703 Daltons by the latter procedure. The physical and biochemical properties of this protein kinase regulator suggest that it is a phospholipid but it did not co-elute by HPLC or by TLC with any of the known phospholipid activators of protein kinase C.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1023/A:1006836826926
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