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  • 1
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    Membrane depolarization induces p140trk and NGF responsiveness, but not p75LNGFR, in MAH cells (1992)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1992-07-17
    Beschreibung: Nerve growth factor (NGF) is required for the maturation and survival of sympathetic neurons, but the mechanisms controlling expression of the NGF receptor in developing neuroblasts have not been defined. MAH cells, an immortalized sympathoadrenal progenitor cell line, did not respond to NGF and expressed neither low-affinity NGF receptor (p75) nor p140trk messenger RNAs. Depolarizing concentrations of potassium chloride, but none of a variety of growth factors, induced expression of p140trk but not p75 messenger RNA. A functional response to NGF was acquired by MAH cells under these conditions, suggesting that expression of p75 is not essential for this response. Depolarization also permitted a relatively high proportion of MAH cells to develop and survive as neurons in fibroblast growth factor and NGF. These data establish a relation between electrical activity and neurotrophic factor responsiveness in developing neurons, which may operate in the functioning of the mature nervous system as well.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Birren, S J -- Verdi, J M -- Anderson, D J -- NS23476/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1992 Jul 17;257(5068):395-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biology, California Institute of Technology, Pasadena 91125.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1321502" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Blotting, Northern ; Cell Line ; Cell Line, Transformed ; Cell Membrane/*physiology ; Dose-Response Relationship, Drug ; Membrane Potentials ; Nerve Growth Factors/*biosynthesis ; Neurons/*metabolism/*physiology ; Potassium Chloride/pharmacology ; Proto-Oncogene Proteins/*biosynthesis ; RNA, Messenger/*biosynthesis ; Receptor, trkA ; Receptors, Cell Surface/*biosynthesis ; Receptors, Nerve Growth Factor ; Signal Transduction ; Time Factors ; Tretinoin/pharmacology
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes (1995)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1995-03-03
    Beschreibung: The neuron-restrictive silencer factor (NRSF) binds a DNA sequence element, called the neuron-restrictive silencer element (NRSE), that represses neuronal gene transcription in nonneuronal cells. Consensus NRSEs have been identified in 18 neuron-specific genes. Complementary DNA clones encoding a functional fragment of NRSF were isolated and found to encode a novel protein containing eight noncanonical zinc fingers. Expression of NRSF mRNA was detected in most nonneuronal tissues at several developmental stages. In the nervous system, NRSF mRNA was detected in undifferentiated neuronal progenitors, but not in differentiated neurons. NRSF represents the first example of a vertebrate silencer protein that potentially regulates a large battery of cell type-specific genes, and therefore may function as a master negative regulator of neurogenesis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schoenherr, C J -- Anderson, D J -- NS23476/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1995 Mar 3;267(5202):1360-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Biology 216-76, California Institute of Technology, Pasadena 91125.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7871435" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Amino Acid Sequence ; Animals ; Base Sequence ; Brain-Derived Neurotrophic Factor ; Cell Line ; Central Nervous System/chemistry/cytology/embryology ; DNA, Complementary/genetics ; DNA-Binding Proteins/analysis/chemistry/genetics/*physiology ; *Gene Expression Regulation ; Humans ; Intracellular Signaling Peptides and Proteins ; Membrane Proteins ; Mice ; Molecular Sequence Data ; Nerve Growth Factors/genetics ; Nerve Tissue Proteins/genetics ; Neurons/chemistry ; *Regulatory Sequences, Nucleic Acid ; Repressor Proteins/physiology ; Sodium Channels/genetics ; Stem Cells/chemistry ; Synapsins/genetics ; Transcription Factors/analysis/chemistry/genetics/*physiology ; Transcription, Genetic ; Transfection ; Zinc Fingers
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Clinical chemistry (1991)
    s.l. : American Chemical Society
    Analytical chemistry 63 (1991), S. 165-270 
    Details
    ISSN: 1520-6882
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/ac00012a011
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  • 4
    Digitale Medien
    Digitale Medien
    Photodissociation dynamics of carbon suboxide at 193 and 248 nm (1991)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 94 (1991), S. 7857-7867 
    Details
    ISSN: 1089-7690
    Quelle: AIP Digital Archive
    Thema: Physik , Chemie und Pharmazie
    Notizen: The nascent CO vibrational, rotational, and translational energies, following the UV photolysis of carbon suboxide at 193 and 248 nm, were determined by time-resolved tunable diode laser infrared absorption spectroscopy. A statistical model for energy disposal fits the experimentally observed vibrational distributions and average translational energies at both photolysis wavelengths. The model fails to account for the experimental rotational distributions that are much "colder'' than the model predictions. An impulsive model for dissociation could not account for the observed energy partitioning at both photolysis wavelengths. These results suggest that at 193 nm the primary photoproducts are CO(X1Σ+) and C2O(a˜1Δ), and that at 248 nm the primary photoproducts are CO(X1Σ+) and C2O(X˜3Σ−).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.460121
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  • 5
    Digitale Medien
    Digitale Medien
    Ultraviolet Raman scattering from simple alcohols and a related diol as a study of low-lying Rydberg-valence state characteristics (1993)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 99 (1993), S. 6245-6252 
    Details
    ISSN: 1089-7690
    Quelle: AIP Digital Archive
    Thema: Physik , Chemie und Pharmazie
    Notizen: Relative Raman scattering cross sections of totally symmetric vibrational modes of liquid methanol, ethanol, and ethylene glycol are measured as a function of excitation wavelength in the preresonant spectral region 37 593–47 393 cm−1. Raman spectra are also obtained with 50 043 and 54 198 cm−1 excitation, the latter energy being directly resonant with the first excited state of the alcohols. The data indicate that the first three excited electronic states (with transition energies of approximately 54 600, 62 500, and 66 000 cm−1, respectively) make no significant contribution to the Raman scattered intensities and are nearly entirely Rydberg in character. The low-lying electronic structure of ethylene glycol appears to be primarily Rydberg in character as well. The dominant C–H and O–H stretching modes gain intensity largely from valence state(s) with transition energies near 70 000 cm−1, while the C–O stretching and CH2,3 bending modes gain intensity from even higher energy states (∼85 000 cm−1).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.465889
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  • 6
    Digitale Medien
    Digitale Medien
    Fiber-optic-bundle delivery system for high peak power laser particle image velocimetry illumination (1996)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 67 (1996), S. 2675-2679 
    Details
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: We demonstrate the design and implementation of a fiber-optic-bundle beam delivery system for particle image velocimetry (PIV) applications. The system is designed for the transmission of high peak power pulses ((approximately-greater-than)20 mJ) from a Q-switched and frequency doubled Nd:YAG laser. A fiber bundle offers advantages over a single fiber in beam delivery systems for light sheet formation. The damage-limit-maximum power that can be transmitted is greater for the bundle than for any of its component fibers, and the quality of the derived light sheet is higher than that obtainable from a single large core fiber of power handling capacity equivalent to that of the bundle. The beam delivery system was demonstrated in PIV measurements on a premixed propane-air flame. © 1996 American Institute of Physics.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.1147093
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  • 7
    Digitale Medien
    Digitale Medien
    Molecular Control of Cell Fate in the Neural Crest: The Sympathoadrenal Lineage (1993)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Neuroscience 16 (1993), S. 129-158 
    Details
    ISSN: 0147-006X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1146/annurev.ne.16.030193.001021
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  • 8
    Digitale Medien
    Digitale Medien
    Evidence of kin-selected tolerance by nestlings in a siblicidal bird (1995)
    Springer
    Behavioral ecology and sociobiology 37 (1995), S. 163-168 
    Details
    ISSN: 1432-0762
    Schlagwort(e): Key words Siblicide ; Kin selection ; Galápagos Islands ; Blue-footed booby ; Sula nebouxii
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Behaviorally dominant members of blue-footed booby (Sula nebouxii) broods can effect siblicide by restricting access of subordinate siblings to parents providing food. In spite of their capacity for siblicide, dominant chicks permit subordinates to feed during short-term food shortage; in fact, the proportion of the food that the dominant takes is independent of the total amount delivered in older chicks. A model of optimal food distribution suggests that dominant chicks maximize their inclusive fitness with this pattern, rather than by satisfying their own food requirements and leaving what remains for the subordinate sibling. The indirect reproductive potential represented by a chick’s sibling appears to have influenced the evolution of siblicidal brood reduction in this species.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002650050177
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  • 9
    Digitale Medien
    Digitale Medien
    Evidence of kin-selected tolerance by nestlings in a siblicidal bird (1995)
    Springer
    Behavioral ecology and sociobiology 37 (1995), S. 163-168 
    Details
    ISSN: 1432-0762
    Schlagwort(e): Siblicide ; Kin selection ; Gálapagos Islands ; Blue-footed booby ; Sula nebouxii
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Behaviorally dominant members of blue-footed booby (Sula nebouxii) broods can effect siblicide by restricting access of subordinate siblings to parents providing food. In spite of their capacity for siblicide, dominant chicks permit subordinates to feed during short-term food shortage; in fact, the proportion of the food that the dominant takes is independent of the total amount delivered in older chicks. A model of optimal food distribution suggests that dominant chicks maximize their inclusive fitness with this pattern, rather than by satisfying their own food requirements and leaving what remains for the subordinate sibling. The indirect reproductive potential represented by a chick's sibling appears to have influenced the evolution of siblicidal brood reduction in this species.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00176713
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  • 10
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    The role of complement component C3b and its receptors in sperm-oocyte interaction. (1993)
    National Academy of Sciences
    Details
    Publikationsdatum: 1993-11-01
    Print ISSN: 0027-8424
    Digitale ISSN: 1091-6490
    Thema: Biologie , Medizin , Allgemeine Naturwissenschaft
    Publiziert von National Academy of Sciences
    Standort Signatur Erwartet Verfügbarkeit
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