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  • 2000-2004  (150)
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  • 1
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    Himalayan tectonics explained by extrusion of a low-viscosity crustal channel coupled to focused surface denudation (2001)
    In:  Nature, Leiden, Noordhoff, vol. 414, no. 6865, pp. 738-742, pp. 2371
    Details
    Publication Date: 2001
    Keywords: Tectonics ; Low viscosity zone ; Crustal deformation (cf. Earthquake precursor: deformation or strain) ; Geol. aspects ; Plate tectonics ; China ; Modelling
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    BIBLIOGRAPHY SEISMOLOGY
  • 2
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    A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-04-21
    Description: In both animal and yeast cells, signaling pathways involving small guanosine triphosphatases (GTPases) regulate polarized organization of the actin cytoskeleton. In the budding yeast Saccharomyces cerevisiae, the Ras-like GTPase Bud1/Rsr1 and its guanosine 5'-diphosphate (GDP)/guanosine 5'-triphosphate (GTP) exchange factor Bud5 are involved in the selection of a specific site for growth, thus determining cell polarity. We found that Bud5 is localized at the cell division site and the presumptive bud site. Its localization is dependent on potential cellular landmarks, such as Bud3 and Axl2/Bud10 in haploid cells and Bud8 and Bud9 in diploid cells. Bud5 also physically interacts with Axl2/Bud10, a transmembrane glycoprotein, suggesting that a receptor-like transmembrane protein recruits a GDP/GTP exchange factor to connect an intrinsic spatial signal to oriented cell growth.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386611/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386611/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kang, P J -- Sanson, A -- Lee, B -- Park, H O -- R01 GM056997/GM/NIGMS NIH HHS/ -- R01 GM056997-02/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2001 May 18;292(5520):1376-8. Epub 2001 Apr 19.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Genetics, The Ohio State University, Columbus, OH 43210-1292, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11313501" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Division ; *Cell Polarity ; Diploidy ; Fungal Proteins/genetics/*metabolism ; Genes, Fungal/genetics ; Genotype ; Guanine Nucleotide Exchange Factors ; Guanosine Diphosphate/metabolism ; Guanosine Triphosphate/metabolism ; Haploidy ; Membrane Glycoproteins/genetics/metabolism ; Mutation/genetics ; Precipitin Tests ; Protein Binding ; Recombinant Fusion Proteins/metabolism ; Saccharomyces cerevisiae/*cytology/genetics/*metabolism ; *Saccharomyces cerevisiae Proteins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 3
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    Protein nanoarrays generated by dip-pen nanolithography (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-02-09
    Description: Dip-pen nanolithography was used to construct arrays of proteins with 100- to 350-nanometer features. These nanoarrays exhibit almost no detectable nonspecific binding of proteins to their passivated portions even in complex mixtures of proteins, and therefore provide the opportunity to study a variety of surface-mediated biological recognition processes. For example, reactions involving the protein features and antigens in complex solutions can be screened easily by atomic force microscopy. As further proof-of-concept, these arrays were used to study cellular adhesion at the submicrometer scale.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, Ki-Bum -- Park, So-Jung -- Mirkin, Chad A -- Smith, Jennifer C -- Mrksich, Milan -- New York, N.Y. -- Science. 2002 Mar 1;295(5560):1702-5. Epub 2002 Feb 7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Northwestern University, Department of Chemistry and Center for Nanofabrication and Molecular Self-Assembly, 2145 Sheridan Road, Evanston, IL 60208, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11834780" target="_blank"〉PubMed〈/a〉
    Keywords: 3T3 Cells ; Adsorption ; Animals ; Cell Adhesion ; *Fibronectins/chemistry/metabolism ; Focal Adhesions ; *Immunoglobulin G/chemistry/metabolism ; Mice ; Microscopy, Atomic Force ; Miniaturization ; *Muramidase/chemistry/metabolism ; *Nanotechnology ; Palmitic Acids/*chemistry ; Protein Binding ; *Proteins/chemistry/metabolism ; Receptor Aggregation ; Recombinant Proteins/chemistry/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Antibody-based bio-nanotube membranes for enantiomeric drug separations (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-06-22
    Description: Synthetic bio-nanotube membranes were developed and used to separate two enantiomers of a chiral drug. These membranes are based on alumina films that have cylindrical pores with monodisperse nanoscopic diameters (for example, 20 nanometers). Silica nanotubes were chemically synthesized within the pores of these films, and an antibody that selectively binds one of the enantiomers of the drug was attached to the inner walls of the silica nanotubes. These membranes selectively transport the enantiomer that specifically binds to the antibody, relative to the enantiomer that has lower affinity for the antibody. The solvent dimethyl sulfoxide was used to tune the antibody binding affinity. The enantiomeric selectivity coefficient increases as the inside diameter of the silica nanotubes decreases.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, Sang Bok -- Mitchell, David T -- Trofin, Lacramioara -- Nevanen, Tarja K -- Soderlund, Hans -- Martin, Charles R -- New York, N.Y. -- Science. 2002 Jun 21;296(5576):2198-200.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry and Center for Research at the Bio/Nano Interface, University of Florida, Gainesville, FL 32611-7200, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12077410" target="_blank"〉PubMed〈/a〉
    Keywords: Aluminum Oxide ; *Antibodies ; Diffusion ; Dimethyl Sulfoxide ; Membranes, Artificial ; *Nanotechnology ; Nitriles/*chemistry/immunology/*isolation & purification ; Permeability ; Silicon Dioxide ; *Stereoisomerism ; *Technology, Pharmaceutical ; Triazoles/*chemistry/immunology/*isolation & purification
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Statewide Tuskegee Alliance for clinical trials (2001)
    Wiley
    Details
    Publication Date: 2001-01-01
    Print ISSN: 0008-543X
    Electronic ISSN: 1097-0142
    Topics: Biology , Medicine
    Published by Wiley on behalf of American Cancer Society.
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  • 6
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    A Statistical Sea-Breeze Prediction Algorithm for Charleston, South Carolina (2003)
    American Meteorological Society
    Details
    Publication Date: 2003-08-01
    Print ISSN: 0882-8156
    Electronic ISSN: 1520-0434
    Topics: Geography , Physics
    Published by American Meteorological Society
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  • 7
    Electronic Resource
    Electronic Resource
    Dose–Tissue Relationships for Dieldrin in Nestling Black-Billed Magpies (2000)
    Springer
    Bulletin of environmental contamination and toxicology 65 (2000), S. 427-434 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s0012800025
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    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    De-esterification and Transacylation Reactions of Pectinesterase from Jelly Fig (Ficus awkeotsang Makino) Achenes (2001)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 66 (2001), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: : Pectinesterase (PE) was isolated from jelly fig (Ficus awkeotsang Makino) achenes, then the optimal conditions for de-esterification and transacylation reactions were determined. Molecular weight of pectin (DE = 62.8 %) when reacted with PE at pH 6.5 and 45 °C in 0.2 M NaCl for 20 min remarkably increased from the original 72 kDa to 410 kDa, as determined by Fractogel TSK 65(S) gel permeation chromatography. Prolonging the incubation time of pectin-PE mixtures to 2 and 4 h also increased the molecular weights of pectin. Therefore, transacylation reaction was considered to occur and to increase the molecular weight of pectins when de-esterification reaction was catalyzed by pectinesterase (PE).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2001.tb15178.x
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  • 9
    Electronic Resource
    Electronic Resource
    Himalayan tectonics explained by extrusion of a low-viscosity crustal channel coupled to focused surface denudation (2001)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 414 (2001), S. 738-742 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Recent interpretations of Himalayan–Tibetan tectonics have proposed that channel flow in the middle to lower crust can explain outward growth of the Tibetan plateau, and that ductile extrusion of high-grade metamorphic rocks between coeval normal- and thrust-sense shear zones can explain ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/414738a
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  • 10
    Electronic Resource
    Electronic Resource
    Response of tundra ecosystem in southwestern Alaska to Younger-Dryas climatic oscillation (2002)
    Oxford, UK : Blackwell Science Ltd
    Global change biology 8 (2002), S. 0 
    Details
    ISSN: 1365-2486
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Geography
    Notes: Climatic warming during the last glacial–interglacial transition (LGIT) was punctuated by reversals to glacial-like conditions. Palaeorecords of ecosystem change can help document the geographical extent of these events and improve our understanding of biotic sensitivity to climatic forcing. To reconstruct ecosystem and climatic variations during the LGIT, we analyzed lake sediments from southwestern Alaska for fossil pollen assemblages, biogenic-silica content (BSiO2%), and organic-carbon content (OC%). Betula shrub tundra replaced herb tundra as the dominant vegetation of the region around 13 600 cal BP (cal BP: 14C calibrated calendar years before present), as inferred from an increase of Betula pollen percentages from 〈〈 5% to 〉〉 20% with associated decreases in Cyperaceae, Poaceae, and Artemisia. At c. 13 000 cal BP, a decrease of Betula pollen from 28 to 〈〈 5% suggests that shrub tundra reverted to herb tundra. Shrub tundra replaced herb tundra to resume as the dominant vegetation at 11 600 cal BP. Higher OC% and BSiO2% values suggest more stable soils and higher aquatic productivity during shrub-tundra periods than during herb-tundra periods, although pollen changes lagged behind changes in the biogeochemical indicators before c. 13 000 cal BP. Comparison of our palaeoecological data with the ice-core dδ18O record from Greenland reveals strikingly similar patterns from the onset through the termination of the Younger Dryas (YD). This similarity supports the hypothesis that, as in the North Atlantic region, pronounced YD climatic oscillations occurred in the North Pacific region. The rapidity and magnitude of ecological changes at the termination of the YD are consistent with greenhouse experiments and historic photographs demonstrating tundra sensitivity to climatic forcing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2486.2002.00550.x
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