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  • Articles  (104)
  • Other Sources  (1)
  • 2000-2004  (105)
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  • Articles  (104)
  • Other Sources  (1)
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  • 1
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    Seismic observation of narrow plumes in the oceanic upper mantle (2003)
    In:  Geophys. Res. Lett., Amsterdam, 4, vol. 30, no. 6, pp. 67-1 to 67-4, pp. 1334, (ISSN: 1340-4202)
    Details
    Publication Date: 2003
    Keywords: Seismology ; hot ; spot ; Plate tectonics ; Deep seismic sounding (espec. cont. crust)
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    BIBLIOGRAPHY SEISMOLOGY
  • 2
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    Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-10-18
    Description: The Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 are critical signaling regulators in mammalian cells. The deletion of both Rac1 and Rac2 murine alleles leads to a massive egress of hematopoietic stem/progenitor cells (HSC/Ps) into the blood from the marrow, whereas Rac1-/- but not Rac2-/- HSC/Ps fail to engraft in the bone marrow of irradiated recipient mice. In contrast, Rac2, but not Rac1, regulates superoxide production and directed migration in neutrophils, and in each cell type, the two GTPases play distinct roles in actin organization, cell survival, and proliferation. Thus, Rac1 and Rac2 regulate unique aspects of hematopoietic development and function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gu, Yi -- Filippi, Marie-Dominique -- Cancelas, Jose A -- Siefring, Jamie E -- Williams, Emily P -- Jasti, Aparna C -- Harris, Chad E -- Lee, Andrew W -- Prabhakar, Rethinasamy -- Atkinson, Simon J -- Kwiatkowski, David J -- Williams, David A -- DK62757/DK/NIDDK NIH HHS/ -- New York, N.Y. -- Science. 2003 Oct 17;302(5644):445-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14564009" target="_blank"〉PubMed〈/a〉
    Keywords: Actins/metabolism ; Animals ; Apoptosis ; Bone Marrow Transplantation ; Cell Adhesion ; Cell Cycle ; Cell Movement ; Cell Size ; Colony-Forming Units Assay ; Cyclin D1/metabolism ; Fibronectins/metabolism ; Hematopoiesis ; Hematopoietic Stem Cell Mobilization ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/*physiology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Mitogen-Activated Protein Kinases/metabolism ; Neutrophils/*physiology ; *Protein-Serine-Threonine Kinases ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-akt ; Recombination, Genetic ; Signal Transduction ; Stem Cell Factor/pharmacology ; Superoxides/metabolism ; rac GTP-Binding Proteins/genetics/*metabolism ; rac1 GTP-Binding Protein/genetics/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 3
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    A new species in the genus Ropalophorus Curtis (Hymenoptera: Braconidae) from China, parasitizing adults of the bark beetle Ips subelongatus (Coleoptera: Scolytidae), with a key to world species of the genus (2003)
    In:  Zoologische Mededelingen vol. 77, 15-36, pp. 631-636
    Details
    Publication Date: 2024-01-12
    Description: A new species of the genus Ropalophorus Curtis (Hymenoptera: Braconidae: Euphorinae) from Palaearctic China is described and illustrated. A key to world species is added.
    Keywords: Hymenoptera ; Braconidae ; Euphorinae ; Ropalophorus ; Coleoptera ; Curculionidae ; Scolytinae ; Ips ; Larix ; distribution ; world ; China ; new species
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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    PAPER (OA)
  • 4
    Electronic Resource
    Electronic Resource
    Direct-method-aided phasing of MAD data (2001)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 57 (2001), S. 250-253 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The direct methods of breaking the phase ambiguity intrinsic in one-wavelength anomalous scattering (OAS) data and MAD phasing are powerful methods in their own rights. In a different context, in addition to their success in phasing OAS data, direct methods can also be useful in the treatment of MAD data. The idea has been tested with the MAD data at 2.5 Å resolution from the protein human adenosine kinase [Mathews et al. (1998), Biochemistry, 37, 15607–15620]. The results showed that the incorporation of direct methods in MAD phasing led to a significant improvement of phases over those obtained from the conventional MAD phasing method alone, as indicated by improved map correlation coefficients (with the existing model), reduced phase errors by 4.5° and improved map connectivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444900018606
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  • 5
    Electronic Resource
    Electronic Resource
    Solving crystal structures from two-wavelength X-ray powder diffraction data – breaking the phase ambiguity in the noncentrosymmetric case (2000)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 56 (2000), S. 592-595 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Direct methods of breaking phase ambiguities in protein crystallography have been introduced in powder diffraction analysis. This is aiming at ab initio solution of noncentrosymmetric structures using two-wavelength anomalous powder diffraction data. The known structure of the hydrogen bromide salt of leotidine (C14H20O2N2·HBr) in space group P212121 was used for simulating two-wavelength anomalous powder diffraction with the Br atom as anomalous scatterer. X-ray wavelengths are selected at \lambda_1 = 0.920 and \lambda_2 = 1.500 Å. Unique reflections from the diffraction pattern of \lambda_2 were able to locate the Br atom accurately. All overlapping diffraction peaks were uniformly partitioned to decompose into single reflections. Structure-factor amplitudes were then extracted. With these and the substructure of Br atoms, unique phases for centric reflections (hk0, h0l and 0kl) and phase doublets for noncentric reflections were obtained. The direct method was used to break the phase ambiguity leading to an interpretable electron-density map, from which five cycles of Fourier iteration yielded the complete structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108767300011417
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  • 6
    Electronic Resource
    Electronic Resource
    Nocardiosis in sea bass, Lateolabrax japonicus, in Taiwan (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of fish diseases 23 (2000), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: An epizootic in pond cultured sea bass, Lateolabrax japonicus, was caused by Nocardia sp. in Taiwan, in September and October 1997. The cumulative mortality within 1 month was 17.5% (3500 out of 20 000 fish) and diseased fish were 7 months old with total lengths from 25 to 30 cm. Multiple, yellowish white nodules, 0.1–0.2 cm in diameter, were scattered in the gill, heart, liver, spleen and kidney. Histopathologically, typical granulomatous lesions appeared in those organs. The morphology of isolated bacteria from brain heart infusion (BHI) medium or Lowenstein–Jensen medium (LJM) were bead-like filaments, as shown by Ziehl-Neelsen's (ZN) staining method. The gross lesion and histopathological changes found in experimentally infected fish were similar to those in naturally infected fish. Based on the growth characteristics, morphological and biochemical properties of the bacterium, and histopathological changes, the isolated bacteria were identified as Nocardiaseriolae. This is the first report of N. seriolae-infected sea bass in aquaculture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2761.2000.00217.x
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  • 7
    Electronic Resource
    Electronic Resource
    A wide-field time-domain fluorescence lifetime imaging microscope with optical sectioning (2002)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 73 (2002), S. 1898-1907 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: This article describes a wide-field time-domain fluorescence lifetime imaging (FLIM) microscope with optical sectioning. The FLIM system utilizes a wide-field time-gated optical image intensifier, with a minimum gate width of 85 ps, to achieve high temporal resolution of fluorescence decays induced by ultrashort laser pulses. Different configurations, using excitation pulses of picojoule energy at 80 MHz repetition rate and of nanojoule energy at 10 kHz, are compared. The instrument has a temporal dynamic range spanning from 100 ps to tens of μs and is shown to have a temporal discrimination better than 10 ps. When applied to laser dye samples, it has produced FLIM maps demonstrating sensitivity to variations in both chemical species and local environment, e.g., viscosity. Wide-field optical sectioning is achieved using the technique of structured illumination, which is applied to remove out-of-focus light that can result in lifetime artifacts. The sectioning strength, which may be adjusted by choosing an appropriate spatial modulation frequency, is characterized and shown to be comparable to that of a confocal microscope. Practical considerations concerned with improving the quality of sectioned fluorescence lifetime maps, including using a large bit depth camera, are discussed. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1458061
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  • 8
    Electronic Resource
    Electronic Resource
    OASIS: a computer program for breaking phase ambiguity in one-wavelength anomalous scattering or single isomorphous substitution (replacement) data (2000)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 33 (2000), S. 980-981 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: The phase problem is reduced to a sign problem once the anomalous-scatterer or the replacing-heavy-atom sites are located. OASIS adopts the CCP4 format [Collaborative Computational Project, Number 4 (1994). Acta Cryst. D50, 760–763]. It applies a direct-method procedure to break the phase ambiguity intrinsic to one-wavelength anomalous scattering (OAS) or single isomorphous replacement (SIR) data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889800001424
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  • 9
    Electronic Resource
    Electronic Resource
    Coupling of element free Galerkin and hybrid boundary element methods using modified variational formulation (2000)
    Springer
    Computational mechanics 26 (2000), S. 166-173 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  A novel method is proposed by coupling the element free Galerkin (EFG) and the hybrid boundary element (HBE) methods to achieve solution efficiency and accuracy for stress analysis in solids. A modified variational formulation is derived for the present coupled EFG/HBE method so that the continuity and compatibility can be preserved on the interface between the domains of EFG and HBE. The coupled EFG/HBE method has been coded in FORTRAN. The validity and efficiency of the proposed method are demonstrated through a number of example problems. It is found that the present method can take advantages of both EFG and HBE methods. The present method is very easy to implement, and very flexible for obtaining displacements and stresses of desired accuracy in solids, as the efforts for meshing the problem domain have been significantly reduced due to the use of boundary element method (BEM).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660000164
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  • 10
    Electronic Resource
    Electronic Resource
    Meshless local Petrov–Galerkin (MLPG) method in combination with finite element and boundary element approaches (2000)
    Springer
    Computational mechanics 26 (2000), S. 536-546 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The meshless local Petrov–Galerkin (MLPG) method is an effective truly meshless method for solving partial differential equations using moving least squares (MLS) interpolants. It is, however, computationally expensive for some problems. A coupled MLPG/finite element (FE) method and a coupled MLPG/boundary element (BE) method are proposed in this paper to improve the solution efficiency. A procedure is developed for the coupled MLPG/FE method and the coupled MLPG/BE method so that the continuity and compatibility are preserved on the interface of the two domains where the MLPG and FE or BE methods are applied. The validity and efficiency of the MLPG/FE and MLPG/BE methods are demonstrated through a number of examples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660000203
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