ISSN:
0935-6304
Schlagwort(e):
Monofunctionalized cyclodextrins
;
enantioselective capillary-HPLC
;
immobilized chiral stationary phases
;
separation of chiral drugs
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
---Heptakis(2,6-di-O-methyl-3-O-pentyl)-β-cyclodextrin was monofunctionalized by the regioselective introduction of exactly one ω-epoxyoctyl group at the primary site of the cyclodextrin. The site-specifically substituted cyclodextrin was immobilized to commercially available aminopropyl silica by nucleophilic opening of the epoxy function of the spacer substituent resulting in a lipophilic chiral stationary phase with broad applicability for enantiomer separations in capillary-HPLC under reversed-phase conditions.
Zusätzliches Material:
6 Ill.
Materialart:
Digitale Medien
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