ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    facet.materialart.
    Unknown
    Cell biology: Arrest by ribosome (2009)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2009-05-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ferreira-Cerca, Sebastien -- Hurt, Ed -- England -- Nature. 2009 May 7;459(7243):46-7. doi: 10.1038/459046a.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19424147" target="_blank"〉PubMed〈/a〉
    Keywords: Aging/physiology ; Animals ; Apoptosis/physiology ; Cell Cycle/*physiology ; Gene Expression Regulation ; Genes, p53/genetics ; Humans ; Protein Stability ; Ribosome Subunits, Small, Eukaryotic/metabolism/physiology ; Ribosomes/metabolism/*physiology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Cellular senescence in aging primates (2006)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2006-02-04
    Description: The aging of organisms is characterized by a gradual functional decline of all organ systems. Mammalian somatic cells in culture display a limited proliferative life span, at the end of which they undergo an irreversible cell cycle arrest known as replicative senescence. Whether cellular senescence contributes to organismal aging has been controversial. We investigated telomere dysfunction, a recently discovered biomarker of cellular senescence, and found that the number of senescent fibroblasts increases exponentially in the skin of aging baboons, reaching 〉15% of all cells in very old individuals. In addition, the same cells contain activated ataxia-telangiectasia mutated kinase and heterochromatinized nuclei, confirming their senescent status.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Herbig, Utz -- Ferreira, Mark -- Condel, Laura -- Carey, Dee -- Sedivy, John M -- F32 CA099388/CA/NCI NIH HHS/ -- P01 HL028972/HL/NHLBI NIH HHS/ -- P20 RR015578/RR/NCRR NIH HHS/ -- P51 RR013986/RR/NCRR NIH HHS/ -- R01 AG016694/AG/NIA NIH HHS/ -- New York, N.Y. -- Science. 2006 Mar 3;311(5765):1257. Epub 2006 Feb 2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, RI 02903, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16456035" target="_blank"〉PubMed〈/a〉
    Keywords: Aging/*physiology ; Animals ; Ataxia Telangiectasia Mutated Proteins ; Biomarkers ; Cell Aging/*physiology ; Cell Cycle Proteins/metabolism ; DNA Damage ; DNA Replication ; DNA-Binding Proteins/metabolism ; Dermis/cytology ; Female ; Fibroblasts/cytology/*physiology ; Heterochromatin/metabolism ; Male ; Oxidative Stress ; Papio/*physiology ; Protein-Serine-Threonine Kinases/metabolism ; Signal Transduction ; Telomere/physiology ; Tumor Suppressor Proteins/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Planktonic foraminifera of the California Current reflect 20th-century warming (2006)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2006-01-10
    Description: It is currently unclear whether observed pelagic ecosystem responses to ocean warming, such as a mid-1970s change in the eastern North Pacific, depart from typical ocean variability. We report variations in planktonic foraminifera from varved sediments off southern California spanning the past 1400 years. Increasing abundances of tropical/subtropical species throughout the 20th century reflect a warming trend superimposed on decadal-scale fluctuations. Decreasing abundances of temperate/subpolar species in the late 20th century indicate a deep, penetrative warming not observed in previous centuries. These results imply that 20th-century warming, apparently anthropogenic, has already affected lower trophic levels of the California Current.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Field, David B -- Baumgartner, Timothy R -- Charles, Christopher D -- Ferreira-Bartrina, Vicente -- Ohman, Mark D -- New York, N.Y. -- Science. 2006 Jan 6;311(5757):63-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093, USA. dfield@mbari.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16400144" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; California ; *Climate ; *Ecosystem ; Environment ; *Eukaryota/classification ; *Geologic Sediments ; Greenhouse Effect ; Population Density ; Population Dynamics ; Principal Component Analysis ; Seasons ; Temperature ; Time Factors ; *Zooplankton/classification
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Chronic stress causes frontostriatal reorganization and affects decision-making (2009)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2009-08-01
    Description: The ability to shift between different behavioral strategies is necessary for appropriate decision-making. Here, we show that chronic stress biases decision-making strategies, affecting the ability of stressed animals to perform actions on the basis of their consequences. Using two different operant tasks, we revealed that, in making choices, rats subjected to chronic stress became insensitive to changes in outcome value and resistant to changes in action-outcome contingency. Furthermore, chronic stress caused opposing structural changes in the associative and sensorimotor corticostriatal circuits underlying these different behavioral strategies, with atrophy of medial prefrontal cortex and the associative striatum and hypertrophy of the sensorimotor striatum. These data suggest that the relative advantage of circuits coursing through sensorimotor striatum observed after chronic stress leads to a bias in behavioral strategies toward habit.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dias-Ferreira, Eduardo -- Sousa, Joao C -- Melo, Irene -- Morgado, Pedro -- Mesquita, Ana R -- Cerqueira, Joao J -- Costa, Rui M -- Sousa, Nuno -- Intramural NIH HHS/ -- New York, N.Y. -- Science. 2009 Jul 31;325(5940):621-5. doi: 10.1126/science.1171203.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710-057 Braga, Portugal.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19644122" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Atrophy ; Cell Count ; Choice Behavior ; Chronic Disease ; Corpus Striatum/*pathology ; *Decision Making ; Dendrites/pathology ; Frontal Lobe/*pathology ; Habits ; Hypertrophy ; Neural Pathways/pathology ; Neurons/pathology ; Prefrontal Cortex/pathology ; Rats ; Rats, Long-Evans ; Rats, Wistar ; Reinforcement (Psychology) ; Stress, Psychological/*pathology/*psychology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...