ALBERT

Description: Human-induced changes in atmospheric composition are expected to affect primary productivity across terrestrial biomes. Recent changes in productivity have been observed in many forest ecosystems, but low-latitude upper tree line forests remain to be investigated. Here we use dendrochronological methods and isotopic analysis to examine changes in productivity, and their physiological basis, in Abies religiosa (Ar) and Pinus hartwegii (Ph) trees growing in high-elevation forests of central Mexico. Six sites were selected across a longitudinal transect (Transverse Volcanic Axis), from the Pacific Ocean toward the Gulf of Mexico, where mature dominant trees were sampled at altitudes ranging from 3200 to 4000m asl. A total of 60 Ar and 84 Ph trees were analyzed to describe changes in growth (annual-resolution) and isotopic composition (decadal-resolutions) since the early 1900s. Our results show an initial widespread increase in basal area increment (BAI) during the first half of the past century. However, BAI has decreased significantly since the 1950s with accentuated decline after the 1980s in both species and across sites. We found a consistent reduction in atmosphere to wood 13 C discrimination, resulting from increasing water use efficiency (20-60%), coinciding with rising atmospheric CO 2 . Changes in 13 C discrimination were not followed, however, by shifts in tree ring δ 18 O, indicating site- and species-specific differences in water source or uptake strategy. Our results indicate that CO 2 stimulation has not been enough to counteract warming induced drought stress, but other stressors, such as progressive nutrient limitation, could also have contributed to growth decline. Future studies should explore the distinct role of resource limitation (water vs . nutrients) in modulating the response of high-elevation ecosystems to atmospheric change. © 2013 Blackwell Publishing Ltd

Description: Large strike-slip faults in the eastern Betics are interpreted to have developed in a transcurrent setting in response to 4-6 mm/yr of Africa-Iberia NW-SE convergence. However, here we show that some of these faults are transfer faults accommodating heterogeneous late Miocene extension. The north–Cabrera dextral fault and other E–W to NE–SW strike-slip faults in the Sorbas basin were transfer faults produced under SW–NE extension. These faults together with related normal faults form the main boundaries of two sedimentary depocenters active between the Serravallian and the Tortonian. The older north Cabrera depocenter extended between the Serravallian and the early Tortonian (approx. 13.8 to 9 Ma), whilst the younger Gacía depocenter formed in response to late Tortonian extension (approx. 9 to 7.5 Ma). The latter formed to the west of the north Cabrera depocenter by a listric fan of normal faults with SW-directed transport that are linked by dextral and sinistral transfer fault segments. These faults root on a low-angle detachment cutting into the exhumed high-pressure Nevado–Filabride complex rocks at ~0.8 km depth. The present work reveals that 1) this extension was partially coeval with and kinematically linked to sinistral displacement along the Carboneras fault farther south in the Níjar basin; 2) this westward-directed extension produced elongated core-complexes and tilted-blocks to the north of the Carboneras fault and magmatic accretion upon thinned continental crust to the south, probably in response to slab tearing or detachment and associated edge delamination of the Iberian continental lithospheric mantle beneath the Betics.

Description: ABSTRACT Goodea gracilis is an endemic fish that only habitats in some water bodies of Central Mexico that are contaminated with cyanobacteria-producing microcystins (MC); however, a lack of information on this topic prevails. With the aim to generate the first approximation about the physiological changes elicited by cyanobacterium that produce MC congeners in this fish species, specimens born in the laboratory was exposed for 96 h to cell densities of 572.5, 1145, 2290, 4580, and 9160 × 10 6 cells of Microcystis aeruginosa strain LB85/L, and a set of novel endpoint related to hepatic gluconeogenesis (ADH/LDH) and pro-oxidant forces , H 2 O 2 ) in addition to biomarkers of oxidative damage and antioxidant response was evaluated in the liver. Results suggest that high inhibition of protein serine/threonine phosphatase (PP) may trigger many metabolic processes, such as those related to hepatic gluconeogenesis (ADH/LDH) and pro-oxidant , H 2 O 2 , TBARS, ROOH, RC O) as well as antioxidant (SOD, CAT, GPx) response to oxidative stress. Particularly, we observed that inhibition of LDH and PP, and H 2 O 2 increase and TBARS production were the key damages induced by high densities of M. aeruginosa . However, changes between aerobic and anaerobic metabolism related with ROS metabolism and ADH/LDH balance are apparently an acclimation of this fish species to exposure to cyanobacteria or their MCs. Fish species living in environments potentially contaminated with cyanobacteria or their MCs possess mechanisms of acclimation that allow them to offset the damage induced, even in the case of fish that have never been exposed to MCs. © 2014 Wiley Periodicals, Inc. Environ Toxicol, 2014.

Description: Stable isotope ratios of H, C, and O are powerful indicators of a wide variety of planetary geophysical processes, and for Mars they reveal the record of loss of its atmosphere and subsequent interactions with its surface such as carbonate formation. We report in situ measurements of the isotopic ratios of D/H and (18)O/(16)O in water and (13)C/(12)C, (18)O/(16)O, (17)O/(16)O, and (13)C(18)O/(12)C(16)O in carbon dioxide, made in the martian atmosphere at Gale Crater from the Curiosity rover using the Sample Analysis at Mars (SAM)'s tunable laser spectrometer (TLS). Comparison between our measurements in the modern atmosphere and those of martian meteorites such as ALH 84001 implies that the martian reservoirs of CO2 and H2O were largely established ~4 billion years ago, but that atmospheric loss or surface interaction may be still ongoing.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Webster, Chris R -- Mahaffy, Paul R -- Flesch, Gregory J -- Niles, Paul B -- Jones, John H -- Leshin, Laurie A -- Atreya, Sushil K -- Stern, Jennifer C -- Christensen, Lance E -- Owen, Tobias -- Franz, Heather -- Pepin, Robert O -- Steele, Andrew -- MSL Science Team -- Achilles, Cherie -- Agard, Christophe -- Alves Verdasca, Jose Alexandre -- Anderson, Robert -- Anderson, Ryan -- Archer, Doug -- Armiens-Aparicio, Carlos -- Arvidson, Ray -- Atlaskin, Evgeny -- Aubrey, Andrew -- Baker, Burt -- Baker, Michael -- Balic-Zunic, Tonci -- Baratoux, David -- Baroukh, Julien -- Barraclough, Bruce -- Bean, Keri -- Beegle, Luther -- Behar, Alberto -- Bell, James -- Bender, Steve -- Benna, Mehdi -- Bentz, Jennifer -- Berger, Gilles -- Berger, Jeff -- Berman, Daniel -- Bish, David -- Blake, David F -- Blanco Avalos, Juan J -- Blaney, Diana -- Blank, Jen -- Blau, Hannah -- Bleacher, Lora -- Boehm, Eckart -- Botta, Oliver -- Bottcher, Stephan -- Boucher, Thomas -- Bower, Hannah -- Boyd, Nick -- Boynton, Bill -- Breves, Elly -- Bridges, John -- Bridges, Nathan -- Brinckerhoff, William -- Brinza, David -- Bristow, Thomas -- Brunet, Claude -- Brunner, Anna -- Brunner, Will -- Buch, Arnaud -- Bullock, Mark -- Burmeister, Sonke -- Cabane, Michel -- Calef, Fred -- Cameron, James -- Campbell, John -- Cantor, Bruce -- Caplinger, Michael -- Caride Rodriguez, Javier -- Carmosino, Marco -- Carrasco Blazquez, Isaias -- Charpentier, Antoine -- Chipera, Steve -- Choi, David -- Clark, Benton -- Clegg, Sam -- Cleghorn, Timothy -- Cloutis, Ed -- Cody, George -- Coll, Patrice -- Conrad, Pamela -- Coscia, David -- Cousin, Agnes -- Cremers, David -- Crisp, Joy -- Cros, Alain -- Cucinotta, Frank -- d'Uston, Claude -- Davis, Scott -- Day, Mackenzie -- de la Torre Juarez, Manuel -- DeFlores, Lauren -- DeLapp, Dorothea -- DeMarines, Julia -- DesMarais, David -- Dietrich, William -- Dingler, Robert -- Donny, Christophe -- Downs, Bob -- Drake, Darrell -- Dromart, Gilles -- Dupont, Audrey -- Duston, Brian -- Dworkin, Jason -- Dyar, M Darby -- Edgar, Lauren -- Edgett, Kenneth -- Edwards, Christopher -- Edwards, Laurence -- Ehlmann, Bethany -- Ehresmann, Bent -- Eigenbrode, Jen -- Elliott, Beverley -- Elliott, Harvey -- Ewing, Ryan -- Fabre, Cecile -- Fairen, Alberto -- Farley, Ken -- Farmer, Jack -- Fassett, Caleb -- Favot, Laurent -- Fay, Donald -- Fedosov, Fedor -- Feldman, Jason -- Feldman, Sabrina -- Fisk, Marty -- Fitzgibbon, Mike -- Floyd, Melissa -- Fluckiger, Lorenzo -- Forni, Olivier -- Fraeman, Abby -- Francis, Raymond -- Francois, Pascaline -- Freissinet, Caroline -- French, Katherine Louise -- Frydenvang, Jens -- Gaboriaud, Alain -- Gailhanou, Marc -- Garvin, James -- Gasnault, Olivier -- Geffroy, Claude -- Gellert, Ralf -- Genzer, Maria -- Glavin, Daniel -- Godber, Austin -- Goesmann, Fred -- Goetz, Walter -- Golovin, Dmitry -- Gomez Gomez, Felipe -- Gomez-Elvira, Javier -- Gondet, Brigitte -- Gordon, Suzanne -- Gorevan, Stephen -- Grant, John -- Griffes, Jennifer -- Grinspoon, David -- Grotzinger, John -- Guillemot, Philippe -- Guo, Jingnan -- Gupta, Sanjeev -- Guzewich, Scott -- Haberle, Robert -- Halleaux, Douglas -- Hallet, Bernard -- Hamilton, Vicky -- Hardgrove, Craig -- Harker, David -- Harpold, Daniel -- Harri, Ari-Matti -- Harshman, Karl -- Hassler, Donald -- Haukka, Harri -- Hayes, Alex -- Herkenhoff, Ken -- Herrera, Paul -- Hettrich, Sebastian -- Heydari, Ezat -- Hipkin, Victoria -- Hoehler, Tori -- Hollingsworth, Jeff -- Hudgins, Judy -- Huntress, Wesley -- Hurowitz, Joel -- Hviid, Stubbe -- Iagnemma, Karl -- Indyk, Steve -- Israel, Guy -- Jackson, Ryan -- Jacob, Samantha -- Jakosky, Bruce -- Jensen, Elsa -- Jensen, Jaqueline Klovgaard -- Johnson, Jeffrey -- Johnson, Micah -- Johnstone, Steve -- Jones, Andrea -- Joseph, Jonathan -- Jun, Insoo -- Kah, Linda -- Kahanpaa, Henrik -- Kahre, Melinda -- Karpushkina, Natalya -- Kasprzak, Wayne -- Kauhanen, Janne -- Keely, Leslie -- Kemppinen, Osku -- Keymeulen, Didier -- Kim, Myung-Hee -- Kinch, Kjartan -- King, Penny -- Kirkland, Laurel -- Kocurek, Gary -- Koefoed, Asmus -- Kohler, Jan -- Kortmann, Onno -- Kozyrev, Alexander -- Krezoski, Jill -- Krysak, Daniel -- Kuzmin, Ruslan -- Lacour, Jean Luc -- Lafaille, Vivian -- Langevin, Yves -- Lanza, Nina -- Lasue, Jeremie -- Le Mouelic, Stephane -- Lee, Ella Mae -- Lee, Qiu-Mei -- Lees, David -- Lefavor, Matthew -- Lemmon, Mark -- Lepinette Malvitte, Alain -- Leveille, Richard -- Lewin-Carpintier, Eric -- Lewis, Kevin -- Li, Shuai -- Lipkaman, Leslie -- Little, Cynthia -- Litvak, Maxim -- Lorigny, Eric -- Lugmair, Guenter -- Lundberg, Angela -- Lyness, Eric -- Madsen, Morten -- Maki, Justin -- Malakhov, Alexey -- Malespin, Charles -- Malin, Michael -- Mangold, Nicolas -- Manhes, Gerard -- Manning, Heidi -- Marchand, Genevieve -- Marin Jimenez, Mercedes -- Martin Garcia, Cesar -- Martin, Dave -- Martin, Mildred -- Martinez-Frias, Jesus -- Martin-Soler, Javier -- Martin-Torres, F Javier -- Mauchien, Patrick -- Maurice, Sylvestre -- McAdam, Amy -- McCartney, Elaina -- McConnochie, Timothy -- McCullough, Emily -- McEwan, Ian -- McKay, Christopher -- McLennan, Scott -- McNair, Sean -- Melikechi, Noureddine -- Meslin, Pierre-Yves -- Meyer, Michael -- Mezzacappa, Alissa -- Miller, Hayden -- Miller, Kristen -- Milliken, Ralph -- Ming, Douglas -- Minitti, Michelle -- Mischna, Michael -- Mitrofanov, Igor -- Moersch, Jeff -- Mokrousov, Maxim -- Molina Jurado, Antonio -- Moores, John -- Mora-Sotomayor, Luis -- Morookian, John Michael -- Morris, Richard -- Morrison, Shaunna -- Mueller-Mellin, Reinhold -- Muller, Jan-Peter -- Munoz Caro, Guillermo -- Nachon, Marion -- Navarro Lopez, Sara -- Navarro-Gonzalez, Rafael -- Nealson, Kenneth -- Nefian, Ara -- Nelson, Tony -- Newcombe, Megan -- Newman, Claire -- Newsom, Horton -- Nikiforov, Sergey -- Nixon, Brian -- Noe Dobrea, Eldar -- Nolan, Thomas -- Oehler, Dorothy -- Ollila, Ann -- Olson, Timothy -- de Pablo Hernandez, Miguel Angel -- Paillet, Alexis -- Pallier, Etienne -- Palucis, Marisa -- Parker, Timothy -- Parot, Yann -- Patel, Kiran -- Paton, Mark -- Paulsen, Gale -- Pavlov, Alex -- Pavri, Betina -- Peinado-Gonzalez, Veronica -- Peret, Laurent -- Perez, Rene -- Perrett, Glynis -- Peterson, Joe -- Pilorget, Cedric -- Pinet, Patrick -- Pla-Garcia, Jorge -- Plante, Ianik -- Poitrasson, Franck -- Polkko, Jouni -- Popa, Radu -- Posiolova, Liliya -- Posner, Arik -- Pradler, Irina -- Prats, Benito -- Prokhorov, Vasily -- Purdy, Sharon Wilson -- Raaen, Eric -- Radziemski, Leon -- Rafkin, Scot -- Ramos, Miguel -- Rampe, Elizabeth -- Raulin, Francois -- Ravine, Michael -- Reitz, Gunther -- Renno, Nilton -- Rice, Melissa -- Richardson, Mark -- Robert, Francois -- Robertson, Kevin -- Rodriguez Manfredi, Jose Antonio -- Romeral-Planello, Julio J -- Rowland, Scott -- Rubin, David -- Saccoccio, Muriel -- Salamon, Andrew -- Sandoval, Jennifer -- Sanin, Anton -- Sans Fuentes, Sara Alejandra -- Saper, Lee -- Sarrazin, Philippe -- Sautter, Violaine -- Savijarvi, Hannu -- Schieber, Juergen -- Schmidt, Mariek -- Schmidt, Walter -- Scholes, Daniel -- Schoppers, Marcel -- Schroder, Susanne -- Schwenzer, Susanne -- Sebastian Martinez, Eduardo -- Sengstacken, Aaron -- Shterts, Ruslan -- Siebach, Kirsten -- Siili, Tero -- Simmonds, Jeff -- Sirven, Jean-Baptiste -- Slavney, Susie -- Sletten, Ronald -- Smith, Michael -- Sobron Sanchez, Pablo -- Spanovich, Nicole -- Spray, John -- Squyres, Steven -- Stack, Katie -- Stalport, Fabien -- Stein, Thomas -- Stewart, Noel -- Stipp, Susan Louise Svane -- Stoiber, Kevin -- Stolper, Ed -- Sucharski, Bob -- Sullivan, Rob -- Summons, Roger -- Sumner, Dawn -- Sun, Vivian -- Supulver, Kimberley -- Sutter, Brad -- Szopa, Cyril -- Tan, Florence -- Tate, Christopher -- Teinturier, Samuel -- ten Kate, Inge -- Thomas, Peter -- Thompson, Lucy -- Tokar, Robert -- Toplis, Mike -- Torres Redondo, Josefina -- Trainer, Melissa -- Treiman, Allan -- Tretyakov, Vladislav -- Urqui-O'Callaghan, Roser -- Van Beek, Jason -- Van Beek, Tessa -- VanBommel, Scott -- Vaniman, David -- Varenikov, Alexey -- Vasavada, Ashwin -- Vasconcelos, Paulo -- Vicenzi, Edward -- Vostrukhin, Andrey -- Voytek, Mary -- Wadhwa, Meenakshi -- Ward, Jennifer -- Weigle, Eddie -- Wellington, Danika -- Westall, Frances -- Wiens, Roger Craig -- Wilhelm, Mary Beth -- Williams, Amy -- Williams, Joshua -- Williams, Rebecca -- Williams, Richard B -- Wilson, Mike -- Wimmer-Schweingruber, Robert -- Wolff, Mike -- Wong, Mike -- Wray, James -- Wu, Megan -- Yana, Charles -- Yen, Albert -- Yingst, Aileen -- Zeitlin, Cary -- Zimdar, Robert -- Zorzano Mier, Maria-Paz -- New York, N.Y. -- Science. 2013 Jul 19;341(6143):260-3. doi: 10.1126/science.1237961.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109, USA. chris.r.webster@jpl.nasa.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23869013" target="_blank"〉PubMed〈/a〉

Description: The regioselectivity of deprotonation reactions between arene substrates and basic metalating agents is usually governed by the electronic and/or coordinative characteristics of a directing group attached to the benzene ring. Generally, the reaction takes place in the ortho position, adjacent to the substituent. Here, we introduce a protocol by which the metalating agent, a disodium-monomagnesium alkyl-amide, forms a template that extends regioselectivity to more distant arene sites. Depending on the nature of the directing group, ortho-meta' or meta-meta' dimetalation is observed, in the latter case breaking the dogma of ortho metalation. This concept is elaborated through the characterization of both organometallic intermediates and electrophilically quenched products.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Martinez-Martinez, Antonio J -- Kennedy, Alan R -- Mulvey, Robert E -- O'Hara, Charles T -- New York, N.Y. -- Science. 2014 Nov 14;346(6211):834-7. doi: 10.1126/science.1259662.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, UK. ; WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, UK. r.e.mulvey@strath.ac.uk charlie.ohara@strath.ac.uk.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25395533" target="_blank"〉PubMed〈/a〉

Description: P2X7 is a purinergic receptor-channel; its activation by ATP elicits a broad set of cellular actions, from apoptosis to signals for survival. Here, P2X7 expression and function was studied in human ovarian carcinoma (OCA) cells, and biopsies from non-cancerous and cancer patients were analyzed by immunohistochemistry. Ovarian surface epithelium in healthy tissue expressed P2X7 at a high level that was maintained throughout the cancer. The cell lines SKOV-3 and CAOV-3 were used to investigate P2X7 functions in OCA. In SKOV-3 cells, selective stimulation of P2X7 by 2′(3′)-O-(4-benzoylbenzoyl) adenosine-5′-triphosphate (BzATP) induced a dose-dependent increase of intracellular Ca 2+ concentration ([Ca 2+ ] i ) but not cell death. Instead, BzATP increased the levels of phosphorylated ERK and AKT (pERK and pAKT), with an EC 50 of 44 ± 2 and 1.27 ± 0.5 μM, respectively; 10 μM BzATP evoked a maximum effect within 15 min that lasted for 120 min. Interestingly, basal levels of pERK and pAKT were decreased in the presence of apyrase in the medium, strongly suggesting an endogenous, ATP-mediated phenomenon. Accordingly: (i) mechanically stimulated cells generated a [Ca 2+ ] i increase that was abolished by apyrase; (ii) apyrase induced a decrease in culture viability, as measured by the MTS assay for mitochondrial activity; (iii) incubation with 10 μM AZ10606120, a specific P2X7 antagonist and transfection with the dominant negative P2X7 mutant E496A, both reduced cell viability to 70.1 ± 8.9% and to 76.5 ± 5%, respectively, of control cultures. These observations suggested that P2X7 activity was auto-induced through ATP efflux; this increased pERK and pAKT levels that generated a positive feedback on cell viability. © 2014 Wiley Periodicals, Inc.

Description: Terra Nova, 00, 1–8, 2012 Abstract The subducted North Maghrebian passive margin was exhumed in the Tortonian (11–7 Ma) by an upper-crustal brittle-ductile extensional detachment and brittle low-angle normal faults in a continental subduction transform setting. The Temsamane detachment in the eastern Rif is defined by a ductile shear zone approximately 100-m thick with a low-angle ramp geometry that cuts down into the Temsamane fold-nappe stack. The shear zone shows south-westward kinematics and separates lower-greenschist (≈400 °C) metapelites of the Temsamane units below from the anchizone and diagenetic rocks (〈300–200 °C) of the Ketama-Aknoul units above. To the east, the detachment becomes brittle, branching into a listric-fan that cuts through 10–6 Ma sediments and volcanoclastics in the Tres Forcas cape. Both the North Maghrebian and the South Iberian subducted passive margins were exhumed in the Betic and Rif branches of the Gibraltar arc by SW-directed brittle-ductile detachments during the late Miocene in an oblique collisional setting.

Description: The biophysical features of the Argentinean economy are examined using a social metabolism approach. A material flow analysis (MFA) for this economy was conducted for the period 1970–2009. Results show that Argentina follows a resource-intensive and export-oriented development model with a persistent physical trade deficit. Also, Argentina's terms of trade (the average weight in tonnes of imports that can be purchased through the sale of 1 tonne of exports) show a declining trend in the period of study. Argentina's economy shows a pattern typical of countries whose economies are based primarily on exports. Comparisons between Argentina's metabolic profile and the metabolic profile of other countries in Latin America and of Australia and Spain show that the Argentinean economy presents the same pattern as other Latin American exporting economies, and its terms of trade are opposite to those of industrialized economies.

Description: Microbial biofertilizers are becoming an effective tool for sustainable agriculture by means of the reduction of the use of chemical fertilizers. However, the knowledge of each specific plant–microorganism interaction is essential for a correct application. In this study, we analyzed the in vitro plant-growth-promotion mechanisms of a Rhizobium leguminosarum strain named PEPV16 isolated from Phaseolus vulgaris nodules. This strain was able to produce siderophores and indole acetic acid and to solubilize phosphate. Confocal microscopy showed that this strain was able to colonize the roots of two horticultural crops, Lactuca sativa L. (lettuce) and Daucus carota L. (carrot). Strain PEPV16 was also able to promote the plant growth of both plant species increasing the dry matter of shoots and roots of lettuce and carrots, respectively, as well as to increase the uptake of N and P in the edible parts of both plant species. These data confirmed the suitability of Rhizobium as biofertilizer for nonlegumes.